| Budget Amount *help |
¥17,420,000 (Direct Cost: ¥13,400,000、Indirect Cost: ¥4,020,000)
Fiscal Year 2022: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2021: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2020: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2019: ¥8,450,000 (Direct Cost: ¥6,500,000、Indirect Cost: ¥1,950,000)
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| Outline of Final Research Achievements |
Microorganisms are exposed to severe environmental changes during fermentation and production process. In order to make microorganisms tolerant to environmental changes and fermentation processes, it is necessary to elucidate the response mechanisms (metabolic regulation, gene expression regulation, etc.) to environmental changes. In this study, we aimed to elucidate a new environmental response mechanism of the carbon metabolism system via ubiquitin modification in budding yeast. We reported the regulatory mechanism of the triacylglycerol lipase during the cell cycle and the mechanism that fine-tunes ribosome biosynthesis under starvation conditions.
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