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Gestational hypertension and diabetes associated birth outcome, and constant postpartum non-communicable disease risks

Research Project

Project/Area Number 19K24191
Research Category

Grant-in-Aid for Research Activity Start-up

Allocation TypeMulti-year Fund
Review Section 0908:Society medicine, nursing, and related fields
Research InstitutionNagasaki University

Principal Investigator

FERDOUS Farzana  長崎大学, 熱帯医学・グローバルヘルス研究科, 客員研究員 (90848623)

Project Period (FY) 2019-08-30 – 2022-03-31
Project Status Granted (Fiscal Year 2020)
Budget Amount *help
¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2020: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2019: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
KeywordsPregnant women / Hypertension / Gestational diabetes / Non-communicable disease / Pregnancy / Diabetes / Slum
Outline of Research at the Start

Research reveals that people living with scarcity are not only at a greater risk for infectious diseases but also are at increased threat for NCDs including reproductive age women.Therefore,the information will be obtained from this study will lead to a better understanding of the requirements of appropriate interventions in a larger population that are needed to reduce pregnancy-induced NCDs burden and adverse birth outcome. It will have also value in the reduction of diabetes as well as cardiovascular disease incidence at later diseases trajectory and will create further research prospect.

Outline of Annual Research Achievements

The aims of this study are to determine the burden and effects of diabetes and hypertension induced by pregnancy in resource limited people and investigate how much these conditions self-resolve at 6-months post-pregnancy or if they may be contributing to the overall burden of non-communicable diseases in Bangladesh. In 2020 fiscal year, the present observational cohort enrolled 384 pregnant women. The mean (sd) age of the pregnant women was 24.4 (5.0) years. Of the 384 pregnant, I have found that the prevalence of pregnancy-induced hypertension (PIH) was 7.8 percent and the prevalence of elevated PIH was 28.5 percent. The prevalence of gestational diabetes was 4.5 percent (HbA1c) and glycemic intolerance 40.6 percent (HbA1c) using WHO criteria.

Current Status of Research Progress
Current Status of Research Progress

4: Progress in research has been delayed.

Reason

Due to COVID-19 outbreaks and government declared locked-down, I had to on hold my ethical clearance process in Bangladesh. Finally, I cleared my ethical clearance in November 2020 and thereafter stated enrolment of pregnant women and baseline data collection from December 2020.

Strategy for Future Research Activity

Recently I am working on baseline manuscripts and aiming to publish in American Journal of Hypertension and PLOS One journals. I aim to publish 2 baseline papers from the collected data for 2 different non-communicable disease outcomes. Additionally, we are collecting birth outcome data over cellphone from the enrolled pregnant women. We will also collect post-pregnancy hypertension and diabetes data after 5/6 months of delivery.

Report

(2 results)
  • 2020 Research-status Report
  • 2019 Research-status Report

URL: 

Published: 2019-09-03   Modified: 2021-12-27  

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