Physical activity in patients with sickle cell disease: Effect on the vascular function, frequency of painful episodes and clinical course of the disease

• Project/Area Number: 19KK0248
• Research Category: Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
• Allocation Type: Multi-year Fund
• Review Section: Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
• Research Institution: Ochanomizu University
• Principal Investigator: tripette julien お茶の水女子大学, 生活科学部, 学部教育研究協力員 (30747481)
• Co-Investigator(Kenkyū-buntansha): 吉田 司 国立研究開発法人医薬基盤・健康・栄養研究所, 国立健康・栄養研究所, 研究員 (20822175) ; 宮地 元彦 国立研究開発法人医薬基盤・健康・栄養研究所, 国立健康・栄養研究所 身体活動研究部, 部長 (60229870)
• Project Period (FY): 2019-10-07 – 2023-03-31
• Project Status: Granted (Fiscal Year 2019)
• Budget Amount: ¥17,030,000 (Direct Cost: ¥13,100,000、Indirect Cost: ¥3,930,000); Fiscal Year 2022: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000); Fiscal Year 2021: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000); Fiscal Year 2020: ¥8,710,000 (Direct Cost: ¥6,700,000、Indirect Cost: ¥2,010,000); Fiscal Year 2019: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
• Keywords: sickle cell disease / physical activity / pain / intervention study / vascular physiology

Outline of Research at the Start

Sickle cell disease is a group of genetic blood disorders with fatal complications, which is mostly prevalent in Africa, Europa and the Americas. This research aims at establishing exercise guidelines to improve the quality of life of patients, in particular those living in developing countries.