Effectiveness of intensive rTMS for post stroke patients with aphasia based on functional MRI and NIRS findings
| Project/Area Number |
20300188
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Jikei University School of Medicine |
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Principal Investigator |
ABO Masahiro Jikei University School of Medicine, 医学部, 教授 (00266587)
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| Co-Investigator(Kenkyū-buntansha) |
KAKUDA Wataru 東京慈恵会医科大学, 医学部, 講師 (00453788)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥14,300,000 (Direct Cost: ¥11,000,000、Indirect Cost: ¥3,300,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2008: ¥10,140,000 (Direct Cost: ¥7,800,000、Indirect Cost: ¥2,340,000)
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| Keywords | 失語症 / rTMS / 右半球 / 左半球 / 回復 / 脳梗塞 / 脳出血 / FMRI |
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| Research Abstract |
Our study demonstrated that application of low-frequency rTMS to an area homologous to the most activated area on pretreatment fMRI with a language task resulted in improvement of language function in aphasic stroke patients without any adverse effects. Therefore, our fMRI-based therapeutic rTMS strategy for chronic stroke patients with aphasia seems feasible and potentially useful neurorehabilitative approach with low-risk symptomatic deterioration.
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Report
(4 results)
Research Products
(20 results)
