| Budget Amount *help |
¥18,850,000 (Direct Cost: ¥14,500,000、Indirect Cost: ¥4,350,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2010: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2009: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2008: ¥10,400,000 (Direct Cost: ¥8,000,000、Indirect Cost: ¥2,400,000)
|
|---|
| Research Abstract |
To advance studies on molecular science of triterpene polyethers and alkaloids, biologically active natural products(secondary metabolites from organisms), their chemical syntheses were carried out. As a result, we have succeeded in determining the entire stereostructure of omaezakianol by the asymmetric total synthesis, developing the chemical synthesis method of isodehydrothyrsiferol, and chemically reproducing biomimetic oxacyclizations of teurilene and ekeberin D_4.In addition, an efficient synthesis of the indeno-tetrahydropyridine skeleton of houamine B has also been accomplished.
|
