Circadian adaptation dynamics of cyanobacterial genome
| Project/Area Number |
20370072
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Molecular biology
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|---|
| Research Institution | Waseda University |
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Principal Investigator |
IWASAKI Hideo Waseda University, 理工学術院, 准教授 (00324393)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥20,670,000 (Direct Cost: ¥15,900,000、Indirect Cost: ¥4,770,000)
Fiscal Year 2010: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2009: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2008: ¥9,880,000 (Direct Cost: ¥7,600,000、Indirect Cost: ¥2,280,000)
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|---|
| Keywords | シアノバクテリア / 概日リズム / 明暗応答 / 環境適応 / Synechococcus / 環境応答 / シグマ因子 / kai遺伝子 / マイクロアレイ |
|---|
| Research Abstract |
Based on microarray analysis combined with molecular genetics, we revealed that more than one third of genes on the genome exhibit significant circadian transcription rhythms with peaking at either subjective dawn or dusk under continuous light conditions. When cells were transferred to the dark, most of gene expression was dramatically suppressed and gave rise to serious discrepancy between transcriptomic and proteomic profiles. Moreover, we found less than 8% of genes on the genome were induced even in the dark, and most of them were under the control of the Kai proteins. Since the kai gene mRNAs were rapidly lost in the dark, our observation revealed the first example of clock-controlled transcription without de novo clock gene expression.
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Report
(4 results)
Research Products
(55 results)
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[Presentation] 概日リズムの低温限界2011
Author(s)
陳墨淵, 村山依子, 伊藤浩史, 郡宏, 岩崎秀雄
Organizer
日本植物生理学会
Place of Presentation
東北大学(大震災対応として大会成立承認済み)
Year and Date
2011-03-20
Related Report
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[Presentation] 概日リズムの低温限界2011
Author(s)
陳墨淵, 村山依子, 伊藤浩史, 郡宏, 岩崎秀雄
Organizer
時間生物学フォーラム東京
Place of Presentation
早稲田大学
Year and Date
2011-02-12
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