Fabrication of cancel. ous bone type bone replacement

• Project/Area Number: 20390500
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Dental engineering/Regenerative dentistry
• Research Institution: Kyushu University
• Principal Investigator: ISHIKATA Kun10 九州大学, 大学院・歯学研究院, 教授 (90202952)
• Co-Investigator(Renkei-kenkyūsha): MATUYA Shigeki 福岡歯科大学, 歯学部, 教授 (00108755) ; MIYAMOTO Youji 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 教授 (20200214) ; TAKECHI Akari 九州大学, 大学院・歯学研究院, 学術研究員 (40432918)
• Project Period (FY): 2008 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥18,980,000 (Direct Cost: ¥14,600,000、Indirect Cost: ¥4,380,000); Fiscal Year 2010: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000); Fiscal Year 2009: ¥7,280,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥1,680,000); Fiscal Year 2008: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
• Keywords: 骨置換材 / 炭酸アパタイト / 骨リモデリング / 水熱反応 / 炭酸アパタイトフォーム / 多孔体

Research Abstract

Feasibility of cancellous bone type bone replacement was evaluated by learning the cancellous bone. First,αtricalcium phosphate foam was prepared using polyurethane foalln as a template based on so-called ceralnics foam method. Then, the foam was treated hydrothermally in the presence of ammonium carbonate. Carbonate apatite foaln that has the silnilar interconnected porous structure was found to be prepared. Carbonate apatite foam was found to be replaced by bone when the bone defect was reconstructed by the carbonate apatite foam.

Research Products

• [Journal Article] Effects of sintering temperature on physical and compositional properties Ofα-tricalcium phosphate foam (2010)
  • Author(s): Koh-ichi Udoh, Melvin L Munar, Michito Maruta, Shigeki Matsuya, Kunlo lshikawa
  • Journal Title: Dental Materials Journal Volume: 29(2) Pages: 154-159
• [Journal Article] Reinforcettent of carbonate apatite bone substitutes with carbonate apatite by Ca salt introduction (2010)
  • Author(s): Kanako Matsumoto, Kanii Tsuru, Giichiro Kawachi, Michito Maruta, Shigeki Matsuya, Ichiro Takahashi, Kunio lshikawa
  • Journal Title: Journal of the Ceramic Society of Japan Volume: 118(6) Pages: 521-524
• [Journal Article] Effect of temperature on crystallinity of carbonate apatite foam prepared fromα-tricalcium phosphate by hydrothermal treatttent (2009)
  • Author(s): Akari Takeuchi, Melvin L. Munar, Hanae Wakae, Michito Maruta, Shigeki Matsuya, Kanii Tsuru, Kunlo lshikawa
  • Journal Title: Blo-Medical Materials and Engineering Volume: 9(2-3) Pages: 205-211
• [Journal Article] Fabrication of low-crystallinity hydroxyapatite foam based on the setting reaction ofα-tricalcium phosphate foam (2009)
  • Author(s): Satoshi Karashima, Akari Takeuchi, Shigeki Matsuya, Koh-ichi Udoh, Kiyoshi Koyano, Kunio lshikawa
  • Journal Title: JOurnal of Blomedical Materials Research A. Volume: 88(3) Pages: 628-633
• [Journal Article] Fabricatio of Si-substituted hydroxyapatite foam using calcium silicates. (2008)
  • Author(s): Q. H. M. Shawket Zaman, Akari Takeuchi, Chowdhury Tanira Zaman, Shigeki Matsuya, Kunio lshikawa
  • Journal Title: Journal of the Ceramic Society of Japan Volume: 116 Pages: 88-91
• [Journal Article] Fabrication of macropoFOuS carbonate apatite foam by hydrothermal conversiol of cx-tricalcium phosphate in carbonate solutions. (2008)
  • Author(s): Hanae wakae, Akari Takeuchi, Koich Udoh, Shigeki Matsuya, Melvin Munar, Racuel Z LeGeros, Akihiko Nakasima, Kunio lshikawa
  • Journal Title: Journal of Blomedical Materials Research A Volume: 87(4) Pages: 957-963