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Microvascular Angina in Postmenopausal Women and Effect of Kampo Medicine

Research Project

Project/Area Number 20510248
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Gender
Research InstitutionOita University

Principal Investigator

NAKAGAWA MIKIKO  Oita University, 医学部, 助教 (50244182)

Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2008: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords漢方薬 / 更年期 / 微小血管性狭心症 / 女性 / 性差医療 / 血管内皮機能 / 東洋医学 / 冠血流予備能
Research Abstract

Microvascular angina is a condition characterized by angina-like chest pain with normal coronary angiography and mostly observed in the postmenopausal women. Keishibukuryougan (KBG) is a traditional Kampo medicine and improves microcirculation in peripheral vessel. However, its effect on the coronary microcirculation has not been evaluated. We measured the coronary flow velocity by echo-cardiography and determined the coronary flow velocity reserve before and after oral administration of KBG in young healthy volunteers. KBG significantly improved CFVR, suggested the potential therapeutic usefulness of KBG for coronary microvascular angina.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (2 results)

All 2010

All Presentation (2 results)

  • [Presentation] Acute Effect of Keishibukuryougan, a Kampo Medicine, on Coronary Flow Velocity Reserve in Normal Human Volunteer.2010

    • Author(s)
      Kaori Ezaki, Mikiko Nakagawa, et al.
    • Organizer
      第74回日本循環器学会学術集会
    • Place of Presentation
      京都国際会議場(京都)
    • Year and Date
      2010-03-06
    • Related Report
      2010 Final Research Report
  • [Presentation] Acute Effect of Keishibukuryougan, a Kampo Medicine, on Coronarv Flow Velocity Reserve in Normal Human Volunteer2010

    • Author(s)
      江崎かおり, 中川幹子, 他
    • Organizer
      第74回日本循環器学会学術集会
    • Place of Presentation
      京都国際会議場(京都)
    • Year and Date
      2010-03-06
    • Related Report
      2009 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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