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Gene expression profiling to identify molecular network for seasonal allergic rhinitis

Research Project

Project/Area Number 20590327
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Human genetics
Research InstitutionUniversity of Tsukuba

Principal Investigator

NOGUCHI Emiko  University of Tsukuba, 大学院・人間総合科学研究科, 准教授 (40344882)

Co-Investigator(Kenkyū-buntansha) UCHIDA Kazuhiko  筑波大学, 大学院・人間総合科学研究科, 准教授 (90211078)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords花粉症 / マイクロアレイ / プロテオーム
Research Abstract

We performed microarray analysis and proteomics to identify genes/proteins related to seasonal allergic rhinitis (SAR). We found that IL17RB was significantly up-regulated during natural exposure against Japanese ceder pollens in patients with SAR. Also, we identified that apolipoprotein A4 was significantly up-regulated in SAR patients treated by sublingual immunotherapy compared with those treated with placebo.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (68 results)

All 2011 2010 2009 2008

All Journal Article (43 results) (of which Peer Reviewed: 36 results) Presentation (24 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] A Japanese case of ichthyosis follicularis with atrichia and photophobia syndrome with an MBTPS2 mutation2011

    • Author(s)
      Nakayama J, Iwasaki N, Shin K,Sato H, Kamo M, Ohyama M, Noguchi E, Arinami T
    • Journal Title

      J Hum Genet 56

      Pages: 250-252

    • NAID

      10030658580

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Upregulation of IL17RB during Natural Allergen Exposure in Patients with Seasonal Allergic Rhinitis2011

    • Author(s)
      Matsumoto Y, Noguchi E, Imoto Y, Nanatsue K, Takeshita K, Shibasaki M, Arinami T, Fujieda S
    • Journal Title

      Allergol Int 60

      Pages: 87-92

    • NAID

      10031143303

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] TSLP Promoter Polymorphisms are Associated with Susceptibility to Bronchial Asthma2011

    • Author(s)
      Harada M, Hirota T, Jodo AI, Hitomi Y, Sakashita M, Tsunoda T, Miyagawa T, Doi S, Kameda M, Fujita K, Miyatake A, Enomoto T, Noguchi E, Masuko H, Sakamoto T, Hizawa N, Suzuki Y, Yoshihara S, Adachi M, Ebisawa M, Saito H, Matsumoto K, Nakajima T, Mathias RA, Rafaels N, Barnes KC, Himes BE, Duan QL, Tantisira KG, Weiss ST, Nakamura Y, Ziegler SF, Tamari M
    • Journal Title

      Am J Respir Cell Mol Biol 44

      Pages: 787-93

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Upregulation of IL17RB during natural allergen exposure in patients with seasonal allergic rhinitis2011

    • Author(s)
      Matsumoto Y, Noguchi E, Imoto Y, Nanatsue K, Takeshita K, Shibasaki M, Arinami T, Fujieda S
    • Journal Title

      Allergol Int i

      Volume: 60 Pages: 87-92

    • NAID

      10031143303

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Japanese case of ichthyosis follicularis with atrichia and photophobia syndrome with an MBTPS2 mutation2011

    • Author(s)
      Nakayama J, Iwasaki N, Sllin K, Sato H, Kamo M, Ohyama M, Noguchi E, Arinami T.
    • Journal Title

      J Hum Genet

      Volume: 56 Pages: 250-2

    • NAID

      10030658580

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Contiguous Xp11.4 gene deletion leading to ornithine transcarbamylase deficiency detected by high-density single-nucleotide array2010

    • Author(s)
      Ono M, Tsuda J, Mouri Y, Arai J, Arinami T, Noguchi E.
    • Journal Title

      Clin Pediatr Endcrinol 19

      Pages: 25-30

    • NAID

      10031199606

    • Related Report
      2010 Final Research Report
  • [Journal Article] Apolipoprotein A-IV is a candidate target molecule for the treatment of seasonal allergic rhinitis2010

    • Author(s)
      Makino Y, Noguchi E, Takahashi N, Matsumoto Y, Kubo S, Yamada T, Imoto Y, Ito Y, Osawa Y, Shibasaki M, Uchida K, Meno K, Suzuki H, Okubo K, Arinami T, Fujieda S
    • Journal Title

      J Allergy Clin Immunol 126

      Pages: 1163-9

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Supportive evidence for reduced expression of GNB1L in schizophrenia2010

    • Author(s)
      Ishiguro H, Koga M, Horiuchi Y, Noguchi E, Morikawa M, Suzuki Y, Arai M, Niizato K, Iritani S, Itokawa M, Inada T, Iwata N, Ozaki N, Ujike H, Kunugi H, Sasaki T, Takahashi M, Watanabe Y, Someya T, Kakita A, Takahashi H, Nawa H, Arinami T
    • Journal Title

      Schizophr Bull 36

      Pages: 756-765

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] S2554X mutation in the filaggrin gene is associated with allergen sensitization in the Japanese population2010

    • Author(s)
      Imoto Y, Enomoto H, Fujieda S, Okamoto M, Sakashita M, Susuki D, Okada M, Hirota T, Tamari M, Ebe K, Arinami T, Noguchi E.
    • Journal Title

      J Allergy Clin Immunol 125

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] TSLP Promoter Polymorphisms are Associated with Susceptibility to Bronchial Asthma2010

    • Author(s)
      Harada M, Hirota T, Jodo AI, Hitomi Y, Sakashita M, Tsunoda T, Miyagawa T, Doi S, Kameda M,Fujita K, Miyatake A, Enomoto T, Noguchi E, Masuko H, Sakamoto T, Hizawa N, Suzuki Y, Yoshihara S, Adachi M, Ebisawa M, Saito H, Matsumoto K, Nakajima T, Mathias RA, Rafaels N, Barnes KC, Himes BE, Duan QL, Tantisira KG, Weiss ST, Nakamura Y, Ziegler SF, Tamari M
    • Journal Title

      Am J Respir Cell Mol Biol

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Apolipoprotein A-IV is a candidate target molecule for the treatment of seasonal allergic rhinitis2010

    • Author(s)
      Makino Y, Noguchi E, Takahashi N, Matsumoto Y, Kubo S, Yamada T, Imoto Y, Ito Y, Osawa Y, Shibasaki M, Uchida K, Meno K, Suzuki H, Okubo K, Arinami T, Fujieda S
    • Journal Title

      J Allergy Clin Immunol

      Volume: 126 Pages: 1163-9

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] S2554X mutation in the filaggrin gene is associated with allergen sensitization in the Japanese population2010

    • Author(s)
      Imoto Y, Enomoto H, Fujieda S, Okamoto M, Sakashita M, Susuki D, Okada M, Hirota T, Tamari M, Ebe K, Arinami T, Noguchi E
    • Journal Title

      J Allergy Clin Immunol

      Volume: 125 Pages: 500-500

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Contiguous Xp11.4 gene deletion leading to ornithine transcarbamylase deficiency detected by high-density single-nucleotide array.2010

    • Author(s)
      Ono M, Tsuda J, Mouri Y, Arai J, Arinami T, Noguchi E
    • Journal Title

      Clin Pediatr Endcrinol

      Volume: 19 Pages: 22-35

    • NAID

      10031199606

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] S2554X mutation in the filaggrin gene is associated with allergen sensitization in the Japanese population2010

    • Author(s)
      Imoto Y, Enomoto H, Fujieda S, Okamoto M, Sakashita M, Susuki D, Okada M, Hirota T, Tamari M, Ebe K, Arinami T, Noguchi E
    • Journal Title

      J Allergy Clin Immunol 125

      Pages: 500-500

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Contiguous Xp11.4 gene deletion leading to ornithine transcarbamylase deficiency detected by high-density single-nucleotide array.2010

    • Author(s)
      Ono M, Tsuda J, Mouri Y, Arai J, Arinami T, Noguchi E
    • Journal Title

      Clin Pediatr Endcrinol (印刷中)

    • NAID

      10031199606

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] アレルギー疾患のゲノム解析-その理論と方法2009

    • Author(s)
      野口恵美子
    • Journal Title

      アレルギーの臨床 129

      Pages: 23-29

    • Related Report
      2010 Final Research Report
  • [Journal Article] SMAD3 as an atopic dermatitis susceptibility gene in the Japanese population2009

    • Author(s)
      Otsuka K, Takeshita S, Enomoto H, Takahashi T, Hirota T, Tamari M, Ebe K, Otsuka F, Shibasaki M, Arinami T, Noguchi E.
    • Journal Title

      J Dermatol Sci 55

      Pages: 200-202

    • NAID

      10029371898

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Associations between decay-accelerating factor polymorphisms and allergic respiratory diseases2009

    • Author(s)
      Kawai T, Takeshita S, Imoto Y, Matsumoto Y, Sakashita M, Suzuki D, Shibasaki M, Tamari M, Hirota T, Arinami T, Fujieda S, Noguchi E.
    • Journal Title

      Clin Exp Allergy 39

      Pages: 1508-14

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Large scale genotyping study for asthma in the Japanese population2009

    • Author(s)
      Imada Y, Fujimoto M, Hirata K, Hirota T, Suzuki Y, Saito H, Matsumoto K, Akazawa A, Katsunuma T, Yoshihara S, Ebisawa M, Shibasaki M, Arinami T, Tamari M, Noguchi E.
    • Journal Title

      BMC Res Notes 2

      Pages: 54-54

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Functional analysis of the thymic stromal lymphopoietin variants in human bronchial epithelial cells2009

    • Author(s)
      Harada M, Hirota T, Jodo AI, Doi S, Kameda M, Fujita K, Miyatake A, Enomoto T, Noguchi E, Yoshihara S, Ebisawa M, Saito H, Matsumoto K, Nakamura Y, Ziegler SF, Tamari M
    • Journal Title

      Am J Respir Cell Mol Biol 40

      Pages: 368-374

    • Related Report
      2010 Final Research Report 2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Expression profiling of genes related to asthma exacerbations2009

    • Author(s)
      Aoki T, Matsumoto Y, Hirata K, Ochiai K, Okada M, Ichikawa K, Shibasaki M, Arinami T, Sumazaki R, Noguchi E.
    • Journal Title

      Clin Exp Allergy 39

      Pages: 213-221

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] SMAD3 as an atopic dermatitis susceptibility gene in the Japanese population.2009

    • Author(s)
      Otsuka K, Takeshita S, Enomoto H, Takahashi T, Hirota T, Tamari M, Ebe K, Otsuka F, Shibasaki M, Arinami T, Noguchi E
    • Journal Title

      J Dermatol Sci 55

      Pages: 200-2

    • NAID

      10029371898

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Associations between decay-accelerating factor polymorphisms and allergic respiratory diseases2009

    • Author(s)
      Kawai T, Takeshita S, Imoto Y, Matsumoto Y, Sakashita M, Suzuki D, Shibasaki M, Tamari M, Hirota T, Arinami T, Fujieda S, Noguchi E
    • Journal Title

      Clin Exp Allergy 39

      Pages: 1508-14

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Large scale genotyping study for asthma in the Japanese population.2009

    • Author(s)
      Imada Y, Fujimoto M, Hirata K, Hirota T, Suzuki Y, Saito H, Matsumoto K, Akazawa A, Katsunuma T, Yoshihars S, Ebisawa M, Shibasaki M, Arinami T, Tamari M, Noguchi E
    • Journal Title

      BMC Res Notes 2

      Pages: 54-54

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Expression profiling of genes related to asthma exacerbations.2009

    • Author(s)
      Aoki T, Matsumoto Y, Hirata K, Ochiai K, Okada M, Ichikawa K, Shibasaki M, Arinami T, Sumazaki R, Noguchi E
    • Journal Title

      Clin Exp Allergy 39

      Pages: 213-221

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Expression profiling of genes related to asthma exacerbations2009

    • Author(s)
      Aoki T, Matsumoto Y, Hirata K, Ochiai K, Okada M, Ichikawa K, Shibasaki M, Arinami T, Sumazaki R, Noguchi E
    • Journal Title

      Clin Exp Allergy 39

      Pages: 213-221

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] アレルギー疾患2008

    • Author(s)
      野口恵美子
    • Journal Title

      小児内科 40

      Pages: 1328-1329

    • Related Report
      2010 Final Research Report
  • [Journal Article] 花粉症発症のメカニズムと遺伝子2008

    • Author(s)
      野口恵美子
    • Journal Title

      日本医師会雑誌 136

      Pages: 1965-1969

    • Related Report
      2010 Final Research Report
  • [Journal Article] アレルギー疾患の遺伝要因について2008

    • Author(s)
      野口恵美子
    • Journal Title

      アレルギー・免疫 15

      Pages: 12-18

    • Related Report
      2010 Final Research Report
  • [Journal Article] アレルギー疾患のプロテオミクス2008

    • Author(s)
      牧野有香,野口恵美子
    • Journal Title

      アレルギー・免疫 15

      Pages: 76-84

    • Related Report
      2010 Final Research Report
  • [Journal Article] アトピー性皮膚炎2008

    • Author(s)
      榎本久子,大塚藤男,有波忠雄,野口恵美子
    • Journal Title

      アレルギー・免疫 15

      Pages: 34-39

    • Related Report
      2010 Final Research Report
  • [Journal Article] Alpha-1-antitrypsin and complement component C7 are involved in asthma exacerbation2008

    • Author(s)
      Nishioka T, Uchida K, Meno K, Ishii T, Aoki T, Imada Y, Makino Y, Hirata K, Matsumoto Y, Arinami T, Noguchi E.
    • Journal Title

      Proteomics Clin Appl 2

      Pages: 46-54

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Clinical and genetic analysis of Fabry disease : Report of six cases including three heterozygous females2008

    • Author(s)
      Nagasaki A, Nishie W, Sato K, Oba I, Noguchi E, Akitsu H, Sawamura D, Shimizu H
    • Journal Title

      J Dermatol Sci 52

      Pages: 61-64

    • NAID

      10024457353

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Supportive evidence for reduced expression of GNB1L in schizophrenia2008

    • Author(s)
      Ishiguro H, Koga M, Horiuchi Y, Noguchi E, Morikawa M, Suzuki Y, Arai M, Niizato K, Iritani S, Itokawa M, Inada T, Iwata N, Ozaki N, Ujike H, Kunugi H, Sasaki T, Takahashi M, Watanabe Y, Someya T, Kakita A, Takahashi H, Nawa H, Arinami T
    • Journal Title

      Schizophr Bull

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Genetic polymorphism regulating ORM1-like 3 (Saccharomyces cerevisiae) expression is associated with childhood atopic asthma in a Japanese population2008

    • Author(s)
      Hirota T, Harada M, Sakashita M, Doi S, Miyatake A, Fujita K, Enomoto T, Ebisawa M, Yoshihara S, Noguchi E, Saito H, Nakamura Y, Tamari M
    • Journal Title

      J Allergy Clin Immunol 121

      Pages: 769-770

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Immunological profile in a family with nephrogenic diabetes insipidus with a novel 11 kb deletion in AVPR2 and ARHGAP4 genes2008

    • Author(s)
      Fujimoto M, Imai K, Hirata K, Kashiwagi R, Morinishi Y, Kitazawa K, Sasaki S, Arinami T, Nonoyama S, Noguchi E.
    • Journal Title

      BMC Med Genet 9

      Pages: 42-42

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Filaggrin null mutations are associated with atopic dermatitis and elevated levels of IgE in the Japanese population, family and case-control study2008

    • Author(s)
      Enomoto H, Hirata K, Otsuka K, Kawai T, Takahashi T, Hirota T, Suzuki Y, Tamari M, Otsuka F, Fujieda S, Arinami T, Noguchi E.
    • Journal Title

      J Hum Genet 57

      Pages: 615-621

    • NAID

      10021249695

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Filaggrin null mutations are associated with atopic dermatitis and elevated levels of IgE in the Japanese population, family and case-control study2008

    • Author(s)
      Enomoto H, Hirata K, Otsuka K, Kawai T, Takahashi T, Hirota T, Suzuki Y, Tamari M, Otsuka F, Fujieda S, Arinami T, Noguchi E
    • Journal Title

      J Hum Genet 57

      Pages: 615-621

    • NAID

      10021249695

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Immunological profile in a family with nephrogenic diabetes insi pidus with a novel 11 kb deletion in AVPR2 and ARHGAP4 genes.2008

    • Author(s)
      Fujimoto M, Imai K, Hirata K, Kashiwagi R, Morinishi Y, Kitazawa K, Sasaki S, Arinami T, Nonoyama S, Noguchi E
    • Journal Title

      BMC Med Genet 9

      Pages: 42-42

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genetic polymorphism regulating ORM1-like 3(Saccharomyces cerevisiae) expression is associated with childhood atopic asthma in a Japanese population2008

    • Author(s)
      Hirota T, Harada M, Sakashita M, Doi S, Miyatake A, Fujita K, Enomoto T, Ebisawa M, Yoshihara S, Noguchi E, Saito H, Nakamura Y, Tamari M
    • Journal Title

      J Allergy Clin Immunol 121

      Pages: 769-770

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Supportive evidence for reduced expression of GNB1L in schizophrenia.2008

    • Author(s)
      Ishiguro H, Koga M, Horiuchi Y, Noguchi E, Morikawa M, Suzuki Y, Arai M, Niizato K, Iritani S, Itokawa M, Inada T, Iwata N, Ozaki N, Ujike H, Kunugi H, Sasaki T, Takahashi M, Watanabe Y, Someya T, Kakita A, Takahashi H, Nawa H, Arinami T
    • Journal Title

      Schizophr Bull

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Clinical and genetic analysis of Fabry disease: Report of six cases including three heterozygous females2008

    • Author(s)
      Nagasaki A, Nishie W, Sato K, Oba I, Noguchi E, Akitsu H, Sawamura D, Shimizu H
    • Journal Title

      J Dermatol Sci 52

      Pages: 61-64

    • NAID

      10024457353

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Alpha-l-antitrypsin and complement component C7 are involved in asthma exacerbation2008

    • Author(s)
      Nishioka T, Uchida K, Meno K, Ishii T, Aoki T, Imada Y, Makino Y, Hirata K, Matsumoto Y, Arinami T, Noguchi E
    • Journal Title

      Proteomics Clin Appl 2

      Pages: 46-54

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] ゲノム解析によるアレルギー疾患の疾患感受性遺伝子の同定2011

    • Author(s)
      野口恵美子
    • Organizer
      第19回関東アレルギークラブ
    • Place of Presentation
      東京
    • Year and Date
      2011-02-12
    • Related Report
      2010 Final Research Report
  • [Presentation] 全ゲノム関連解析による疾患感受性遺伝子の同定2010

    • Author(s)
      落合香保里、野口恵美子、有波忠雄、松本健治、斎藤博久
    • Organizer
      第55回日本人類遺伝学会
    • Place of Presentation
      埼玉県・大宮
    • Year and Date
      2010-10-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] 網羅的遺伝子解析によるスギ花粉症発症に関する遺伝子の同定2010

    • Author(s)
      意元義政,野口恵美子,有波忠雄,藤枝重治
    • Organizer
      第60回日本アレルギー学会秋季学術大会
    • Place of Presentation
      東京
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] Proteomics and Transcriptome in Allergic diseases2010

    • Author(s)
      野口恵美子
    • Organizer
      第60回日本アレルギー学会秋季学術大会
    • Place of Presentation
      東京
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] Genome wide association study for pediatric asthma in Asian population2010

    • Author(s)
      野口恵美子
    • Organizer
      第60回日本アレルギー学会秋季学術大会
    • Place of Presentation
      東京
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] 全ゲノム関連解析による疾患感受性遺伝子の同定2010

    • Author(s)
      落合香保里,野口恵美子,有波忠雄,松本健治,斎藤博久
    • Organizer
      第55回日本人類遺伝学会
    • Place of Presentation
      埼玉県大宮
    • Related Report
      2010 Final Research Report
  • [Presentation] Genetic approach to identify susceptibility genes for allergic diseases2009

    • Author(s)
      野口恵美子
    • Organizer
      World Allergy Congress, Buenos Aires
    • Year and Date
      2009-12-08
    • Related Report
      2010 Final Research Report
  • [Presentation] Genetic approach to identify susceptibility genes for allergic diseases2009

    • Author(s)
      Emiko Noguchi
    • Organizer
      World Allergy Congress
    • Place of Presentation
      アルゼンチン、ブエノスアイレス
    • Year and Date
      2009-12-08
    • Related Report
      2009 Annual Research Report
  • [Presentation] 遺伝子とアレルギーナ疾患の性差2009

    • Author(s)
      野口惠美子
    • Organizer
      第46回日本小児アレルギー学会
    • Place of Presentation
      福岡
    • Year and Date
      2009-12-05
    • Related Report
      2009 Annual Research Report
  • [Presentation] 遺伝子とアレルギー疾患の性差2009

    • Author(s)
      野口恵美子
    • Organizer
      シンポジウム2 第46回日本小児アレルギー学会
    • Place of Presentation
      福岡シンポジウム2
    • Related Report
      2010 Final Research Report
  • [Presentation] 網羅的遺伝子発現解析による花粉症発症関連遺伝子の同定と機能解析2009

    • Author(s)
      松元佑莉,意元義政,有波忠雄,野口恵美子,藤枝重治
    • Organizer
      第59回日本アレルギー学会秋季学術大会
    • Place of Presentation
      秋田
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] スギ花粉症未発症者における末梢血白血球分画の動向2009

    • Author(s)
      意元義政,野口恵美子,松元佑莉,有波忠雄,藤枝重治
    • Organizer
      第59回日本アレルギー学会秋季学術大会
    • Place of Presentation
      秋田
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] 全ゲノム関連解析を用いた喘息関連SNPの解析2009

    • Author(s)
      落合香保里,野口恵美子,松本健治,斎藤博久,有波忠雄
    • Organizer
      第54回日本人類遺伝学会
    • Place of Presentation
      東京
    • Related Report
      2010 Final Research Report
  • [Presentation] 高密度DNAアレイを用いたオルニチントランスカルバミラーゼ欠損症における遺伝子欠損領域の同定2009

    • Author(s)
      小野美都穂,落合香保里,野口恵美子,有波忠雄
    • Organizer
      第54回日本人類遺伝学会
    • Place of Presentation
      東京
    • Related Report
      2010 Final Research Report
  • [Presentation] 網羅的遺伝子発現解析による喘息発作関連遺伝子の同定2008

    • Author(s)
      青木健,市川邦男,松元佑莉,落合香保里,有波忠雄,柴崎正修,野口恵美子
    • Organizer
      第45回日本小児アレルギー学会
    • Place of Presentation
      横浜
    • Year and Date
      2008-12-14
    • Related Report
      2010 Final Research Report
  • [Presentation] 網羅的遺伝子発現解析による喘息発作関連遺伝子の同定2008

    • Author(s)
      青木健, 市川邦男, 松元佑莉, 落合香保里, 有波忠雄, 柴崎正修, 野口恵美子, 藤枝重治
    • Organizer
      第45回日本小児アレルギァー学会
    • Place of Presentation
      横浜
    • Year and Date
      2008-12-13
    • Related Report
      2008 Annual Research Report
  • [Presentation] ワークショップ5アレルギー疾患のゲノム解析の最近の話題2008

    • Author(s)
      野口恵美子
    • Organizer
      第58回日本アレルギー学会秋季学術大会
    • Place of Presentation
      東京
    • Year and Date
      2008-11-28
    • Related Report
      2008 Annual Research Report
  • [Presentation] ミニシンポジウム基調講演遺伝子2008

    • Author(s)
      野口恵美子
    • Organizer
      第58回日本アレルギー学会秋季学術大会
    • Place of Presentation
      東京
    • Year and Date
      2008-11-28
    • Related Report
      2008 Annual Research Report
  • [Presentation] ミニシンポジウム 基調講演 遺伝子2008

    • Author(s)
      野口恵美子,浅野浩一郎
    • Organizer
      第58回日本アレルギー学会秋季学術大会
    • Place of Presentation
      東京
    • Related Report
      2010 Final Research Report
  • [Presentation] ワークショップ5 アレルギー疾患のゲノム解析の最近の話題2008

    • Author(s)
      野口恵美子
    • Organizer
      第58回日本アレルギー学会秋季学術大会
    • Place of Presentation
      東京
    • Related Report
      2010 Final Research Report
  • [Presentation] 全ゲノム連鎖解析によるアトピー性皮膚炎疾患感受性遺伝子の機能解析2008

    • Author(s)
      大塚健太,榎本久子,広田朝光,玉利真由美,有波忠雄,野口恵美子
    • Organizer
      第58回日本アレルギー学会秋季学術大会
    • Place of Presentation
      東京
    • Related Report
      2010 Final Research Report 2008 Annual Research Report
  • [Presentation] スギ花粉症の網羅的遺伝子発現解析2008

    • Author(s)
      松元佑莉,意元義政,有波忠雄,野口恵美子,藤枝重治
    • Organizer
      第58回日本アレルギー学会秋季学術大会
    • Place of Presentation
      東京
    • Related Report
      2010 Final Research Report 2008 Annual Research Report
  • [Presentation] 日本人アトピー性皮膚炎とフィラグリン遺伝子変異との関連2008

    • Author(s)
      榎本久子,大塚健太,河合利春,広田朝光,鈴木洋一,玉利真由美,藤枝重治,有波忠雄,野口恵美子
    • Organizer
      第58回日本アレルギー学会秋季学術大会
    • Place of Presentation
      東京
    • Related Report
      2010 Final Research Report
  • [Presentation] フィラグリン機能喪失変異とスギ花粉症発症の関連解析2008

    • Author(s)
      意元義政,野口恵美子,有波忠雄,坂下雅文,広田朝光,玉利真由美,藤枝重治
    • Organizer
      第58回日本アレルギー学会秋季学術大会
    • Place of Presentation
      東京
    • Related Report
      2010 Final Research Report
  • [Patent(Industrial Property Rights)] アレルギー疾患の治療薬且つ治療効果のマーカー2008

    • Inventor(s)
      藤枝重治、野口恵美子, ら
    • Industrial Property Rights Holder
      国立大学法人福井大学、国立大学法人筑波大学
    • Industrial Property Number
      2008-053768
    • Filing Date
      2008-03-04
    • Related Report
      2010 Final Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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