Molecular characterization of the spread of X-chromosome inactivation in an autosome of a boy with a t(X;15)(p21.1;q11.2) translocation
| Project/Area Number |
20590333
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Human genetics
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| Research Institution | Gunma Institute of Public Health and Environmental Sciences |
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Principal Investigator |
SAKAZUME Satoru Gunma Institute of Public Health and Environmental Sciences, 医学部, 講師 (70306174)
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| Co-Investigator(Kenkyū-buntansha) |
NAGAI Toshiro 獨協医科大学, 医学部, 講師 (90296129)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
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| Keywords | エピジェネティックス / メチル化 / 不活化 / 染色体異常 / X染色体転座 / XIST / バイオテクノロジー / ゲノム / 遺伝子 / 遺伝学 / 臨床 |
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| Research Abstract |
We revealed partial inactivation of autosome, using a chromosome and DNA from a patient having Prader-Willy Syndrome like phenotype. Several molecular biological techniques were used for the study.
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Report
(4 results)
Research Products
(10 results)
