Immuno-epidemiological study of Japanese cedar pollinosis

• Project/Area Number: 20590652
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Public health/Health science
• Research Institution: Radiation Effects Research Foundation
• Principal Investigator: OZASA Kotaro Radiation Effects Research Foundation, 広島疫学部, 部長 (20204191)
• Co-Investigator(Kenkyū-buntansha): TAKENAKA Hiroshi 大阪医科大学, 医学部, 教授 (40137162) ; HAMA Takemitsu 京都府立医科大学, 医学研究科, 助教 (90315953) ; YASUDA Makoto 京都府立医科大学, 医学研究科, 助教 (60433273) ; KATO Norito 京都府立医科大学, 医学研究科, 教授 (30244578)
• Project Period (FY): 2008 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000); Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2008: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
• Keywords: 疫学 / スギ花粉症 / 免疫 / アレルギー疾患 / IgE抗体

Research Abstract

A questionnaire survey for symptoms and serum examinations were conducted for the all students/pupils in public elementary and junior-high schools, each of which is only one in a town in the southern Kyoto prefecture. The number of subjects was 277 to 300, and those who underwent the survey were 232 to 242 each year. Exposure to Japanese cedar pollen was evaluated by the total of daily count of pollen that were collected in the air by the Durham method during February to April. The subjects who were positive to Japanese cedar pollen-specific IgE antibody were around 55% each year, and the definite patients of Japanese cedar pollinosis, who were positive to the IgE and had allergic symptoms of eyes and/or nose lasting 3 weeks or longer in March and/or April, were 19 to 25%. The proportion was correlated with the amount of dispersed Japanese cedar pollen.

Research Products

• [Journal Article] 学童のスギ花粉感作についての疫学研究 (2009)
  • Author(s): 竹中洋、小笹晃太郎
  • Journal Title: 実験医学 27 Pages: 3386-3390
• [Journal Article] Atopic Dermatitis, Dry Skin and Serum IgE in Children in a Community in Japan. (2009)
  • Author(s): Wakamori T, Katoh N, Hirano S, Kishimoto S, Ozasa K
  • Journal Title: Int Arch Allergy Immunol 149 Pages: 103-110
  • Peer Reviewed
• [Journal Article] 学童のスギ花粉感作についての疫学研究 (2009)
  • Author(s): 竹中洋
  • Journal Title: 実験医学 27 Pages: 3386-3390
• [Journal Article] A 13-year study of Japanese cedar pollinosis in Japanese schoolchildren. (2008)
  • Author(s): Ozasa K, Hama T, Dejima K, Watanabe Y, Hyo S, Terada T, Araki N, Takenaka H.
  • Journal Title: Allergology International 57 Pages: 175-180
  • NAID: 10021246646
  • Peer Reviewed
• [Journal Article] A 13-year study of Japanese cedar pollinosis in Japanese schoolchildren (2008)
  • Author(s): Ozasa K, Hama T, Dejima K, Watanabe Y, Hyo S, Terada T, Araki N, Takenaka H.
  • Journal Title: Allergology International 57 Pages: 175-180
  • NAID: 10021246646
  • Peer Reviewed
• [Presentation] 地域の小中学生を対象としたスギ花粉症の疫学調査 (2010)
  • Author(s): 小笹晃太郎
  • Organizer: 第22回日本アレルギー学会春期臨床大会
  • Place of Presentation: 京都
  • Year and Date: 2010-05-09
• [Presentation] 気道アレルギーの成立とその制御 (2009)
  • Author(s): 竹中洋
  • Organizer: 第110回日本耳鼻咽喉科学会総会
  • Place of Presentation: 東京
  • Year and Date: 2009-05-14
• [Presentation] 地域小集団におけるIgE 抗体産生の生年コホート効果 (2009)
  • Author(s): 小笹晃太郎、兵佐和子、寺田哲也、荒木南都子、出島健司、浜雄光、安田誠、加藤則人、三谷智子、渡邊能行、竹中洋
  • Organizer: 第19回日本疫学会学術総会
  • Place of Presentation: 金沢
  • Year and Date: 2009-01-23
• [Presentation] 地域小集団におけるIgE抗体産生の生年コホート効果 (2009)
  • Author(s): 小笹晃太郎, 兵佐和子, 寺田哲也, 荒木南都子, 出島健司, 浜雄光, 安田誠, 加藤則人, 三谷智子, 渡邊能行, 竹中洋
  • Organizer: 第19回日本疫学会学術総会
  • Place of Presentation: 金沢
  • Year and Date: 2009-01-23
• [Presentation] スギ花粉飛散量がスギ花粉以外の原特異的IgE 抗体価に与える影響 (2008)
  • Author(s): 小笹晃太郎、兵佐和子、寺田哲也、三谷智子、林恭平、渡邊能行、出島健司、浜雄光、荒木南都子、竹中洋
  • Organizer: 第18回日本疫学会学術総会
  • Place of Presentation: 東京
  • Year and Date: 2008-01-25
• [Book] 大阪医科大学耳鼻咽喉科学、気道アレルギーの成立とその制御 (2009)
  • Author(s): 竹中洋
  • Total Pages: 149