A study on the effects of HBV-DNA integration on non-B non-C hepatocellular carcinoma
| Project/Area Number |
20590762
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Gastroenterology
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| Research Institution | The University of Tokyo |
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Principal Investigator |
YOSHIDA Haruhiko The University of Tokyo, 医学部附属病院, 講師 (60240305)
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| Co-Investigator(Kenkyū-buntansha) |
GOTO Tadashi 東京大学, 医学部附属病院, 助教 (40444088)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 肝細胞癌 / 非B非C肝癌 / HBV-DNA / 非B非C肝障害 / HBV-DNA量 / ラジオ波焼灼療法 / 多変量解析 / HBV既感染 / C型慢性肝炎 / HBc抗体 / Cox比例ハザードモデル / 内臓脂肪 / 非アルコール性脂肪肝炎 |
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| Research Abstract |
We evaluated the influence of HBc antibody seropositivity in (1) the recurrence of non-B non-C hepatocellular carcinoma (HCC) after curative treatment, (2) in the development of HCC among patients with non-B non-C chronic liver disease, and (3) in the development of HCV-related HCC. HBc antibody positivity was found to be a significant risk factor in none. Serum HBV load was associated with the risk of recurrence of HBV-related HCC.
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Report
(4 results)
Research Products
(16 results)
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[Journal Article] Influence of HBcAb seropositivity on the risk of hepatocellular carcinoma in HCV infected patients.2010
Author(s)
Ohki T, Tateishi R, Goto E, Sato T, Masuzaki R, Imamura J, Goto T, Kanai F, Shiina S, Yoshida H, Kawabe T, Omata M
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Journal Title
J Viral Hepatitis. 17
Pages: 91-7
Related Report
Peer Reviewed
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[Journal Article] Visceral fat accumulation is an independent risk factor for hepatocellular carcinoma recurrence after curative treatment inpatients with suspected NASH.2009
Author(s)
Ohki T, Tateishi R, Shiina S, Goto E, Sato T, Nakagawa H, Masuzaki R, Goto T, Hamamura K, Kanai F, Yoshida H, Kawabe T, Omata M
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Journal Title
Related Report
Peer Reviewed
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[Journal Article] Serum level of adiponectin and the risk of liver cancer development.
Author(s)
Arano T, Nakagawa H, Tateishi R, Ikeda H, Uchino K, Enooku K, Goto E, Masuzaki R, Asaoka Y, Kondo Y, Goto T, Shiina S, Omata M, Yoshida H, Koike K
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Journal Title
Related Report
Peer Reviewed
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[Journal Article] Influence of serum HBV DNA load on recurrence of hepatocellular carcinoma after treatment with percutaneous radiofrequency ablation.
Author(s)
Goto T, Yoshida H, Tateishi R, Enooku K, Goto E, Sato T, Ohki T, Masuzaki R, Imamura J, Shiina S, Koike K, Omata M
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Journal Title
Related Report
Peer Reviewed
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[Presentation] Visceral fat accumulation is an independent risk factor f hepatcellular carcinoma recurrence after curative treatment in NASH suspected patients.2008
Author(s)
大木隆正, 建石良介, 椎名秀一朗, 後藤絵里子, 佐藤隆久, 増崎亮太, 五藤忠, 浜村啓介, 金井文彦, 吉田英雄, 川辺隆夫, 小俣政男
Organizer
59th AASLD Annual Meeting
Place of Presentation
San Francisco, USA
Year and Date
2008-10-31
Related Report
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