Therapeutic strategy for prevention of the recurrent middle ear cholesteatoma
| Project/Area Number |
20591974
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Niigata University |
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Principal Investigator |
TAKAHASHI Sugata Niigata University, 医歯学系, 教授 (10154824)
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| Co-Investigator(Kenkyū-buntansha) |
YAMAMOTO Yutaka 新潟大学, 医歯学総合病院, 講師 (10313545)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | 中耳真珠腫 / 治療 / 乳突削開術 / 乳突腔充填術 / 遺残性真珠腫 / 乳突腔削開術 |
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| Research Abstract |
Efficacy of the mastoid obliteration for the patients with middle ear cholesteatoma has been well recognized, however, the long-term stability after this surgical procedure and the risk of residual cholesteatoma are still in discussion. The aims of this study were to demonstrate postoperative stability of the reconstructed posterior canal wall made with bone pate and to evaluate the pathogenesis of residual cholesteatoma in the obliterated mastoid cavity. We successfully established the animal models of mastoid obliteration and residual cholesteatoma.
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Report
(4 results)
Research Products
(13 results)
