Molecular Genetic Studies of bruxism during sleep from the Point of predisposition genetic polymorphism of monoamine
| Project/Area Number |
20592265
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Prosthetic dentistry
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| Research Institution | Okayama University |
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Principal Investigator |
MINAKUCHI Hajime Okayama University, 大学院・医歯薬学総合研究科, 助教 (30325097)
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| Co-Investigator(Kenkyū-buntansha) |
KUBOKI Takuo 岡山大学, 大学院・医歯薬学総合研究科, 教授 (00225195)
MATSUKA Yoshizo 岡山大学, 大学院・医歯薬学総合研究科, 准教授 (90243477)
SOGAWA Norio 岡山大学, 大学院・医歯薬学総合研究科, 准教授 (30236153)
KITAYAMA Shigeo 岡山大学, 大学院・医歯薬学総合研究科, 教授 (80177873)
UEHARA Junji 岡山大学, 医学部・歯学部附属病院, 助教 (10379836)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2008: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 睡眠時ブラキシズム / 顎関節症 / モノアミン / 筋電図 / 貼付型ブラキシズム検出装置 / セロトニン神経系 / 睡眠障害 / 臨床疫学研究 / モノアミン神経系 / セロトニントランスポーター / 簡易貼付型ブラキシズム検出装置 / 臨床疫学 / 菌科補綴学 / 口腔運動器疾患 / 歯科補綴学 / 交絡因子 / 臨床歯学 |
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| Research Abstract |
(1) This project evaluated the night-to-night variability and examine for a systematic alteration on the first night in EMG levels. The results suggested that recordings should be at least 5-6 nights duration to establish a reasonable measure of an individual's average nightly masseter EMG level.
(2) The aim of this study was to compare the uptake ability of serotonin transporter (SERT) from peripheral platelets between severe and non-bruxism human subjects. In response, the SERT ability would be related to sleep bruxism frequency.
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Report
(4 results)
Research Products
(50 results)
