Exploration of oral cancer-specific biomarkers by profiling of NF-KB-dependent molecules
| Project/Area Number |
20592362
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Surgical dentistry
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| Research Institution | The University of Tokushima |
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Principal Investigator |
AZUMA Masayuki The University of Tokushima, 大学院・ヘルスバイオサイエンス研究部, 教授 (20144983)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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|---|
| Keywords | 口腔癌 / バイオマーカー / 増殖因子 / 接着分子 / 蛋白分解酵素 / サイトカイン / ケモカイン |
|---|
| Research Abstract |
(1)It has been suggested that enhanced expression of MMP-9, uPA, COX-2 and cyclin D1 in oral cancer tissues may be biological markers for the development of cancer metastasis. (2)Serum levels of biological markers in oral cancer patients were significantly diminished by cancer treatment. (3)Serum levels of biological markers in oral cancer patients correlated with N-stage and lymphangio-hemangiogenesis.
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Report
(4 results)
Research Products
(48 results)
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[Presentation] 口腔内科の役割と展望2010
Author(s)
東雅之
Organizer
四国アイランド歯科口腔外科 夏期合同研集会
Place of Presentation
坂出グランドホテル(坂出市)
Year and Date
2010-07-24
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