Evaluation of carcinogenicity of rare metal nanoparticles using molecular biological methods
| Project/Area Number |
20710027
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Environmental impact assessment/Environmental policy
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| Research Institution | Kurume University |
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Principal Investigator |
HASEGAWA Go Kurume University, 医学部, 助教 (80383751)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2008: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | ナノ粒子 / レアメタル / 健康影響 / 発癌 |
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| Research Abstract |
Mutagenicity and transformation activity of four rare metals, In_2O_3, Dy_2O_3, WO_3 and Mo, were evaluated. The Ames test revealed that nano-sized Dy_2O_3, In_2O_3 and WO_3 possessed mutagenic potential. With the respect to the result of transformation assay, In_2O_3 and Dy_2O_3 also showed potential ability, although particle size of these rare metals did not affect to their transformation activity.
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Report
(4 results)
Research Products
(7 results)
