Analysis of LTBP-1L protein role in carcinoma cell and application as cancer molecular marker
Project/Area Number |
20790421
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Hygiene
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Research Institution | Kanazawa University |
Principal Investigator |
HIGASHI Tomomi Kanazawa University, 医学系, 助教 (20293342)
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Project Period (FY) |
2008 – 2009
|
Project Status |
Completed (Fiscal Year 2009)
|
Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2008: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
|
Keywords | 癌 / LTBP-1 / TGF-β1 / 一塩基多型 / 分子マーカー / LTBP-1L / SNP / TGF-b1 / 発現解析 / 予後解析 |
Research Abstract |
Latent transforming growth factor (TGF)-β binding protein-1 (LTBP-1) play important roles in the secretion and activation of TGF-β. In this study, to clarify the role of LTBP-1L protein in carcinoma cell, we performed in vitro functional analysis and clinical data analysis. Our results indicate that the LTBP-1L protein can contribute to tumor initiation and progression through the induction of cell growth activity. And we indicated the possibility of the LTBP-1L protein as cancer molecular marker.
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Report
(3 results)
Research Products
(19 results)
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[Journal Article] Phylogenetic analysis of atmospheric halotolerant bacterial communities at high altitude in an Asian dust (KOSA) arrival region, Suzu City.2010
Author(s)
T.Maki, S.Susuki, F.Kobayashi, M.Kakikawa, Y.Tobo, M.Yamada, T.Higashi, A.Matsuki, C.Hong, H.Hasegawa, Y.Iwasaka
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Journal Title
Science of the Total Environment (in press)
Related Report
Peer Reviewed
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[Journal Article] Dustborne Microorganisms in the atmosphere over Asian dust source region, Dunhuang.2008
Author(s)
Kakikawa M, Kobayashi F, Maki T, Yamada M, Higashi T, Chen B, Shi G, Hong C, Tobo Y, Iwasaka Y
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Journal Title
Air Quality Atmosphere and Health 1
Pages: 195-202
NAID
Related Report
Peer Reviewed
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[Journal Article] Ecophysiological analysis of halobacteria in bioaerosol.2008
Author(s)
Maki T, Susuki S, Kobayashi F, Kakikawa M, Yamada M, Higashi T, Chen B, Tobo Y, Hasegawa H, Ueda K, Iwasaka Y
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Journal Title
Journal of Ecotechnology Research 13(4)
Pages: 309-313
NAID
Related Report
Peer Reviewed
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[Journal Article] Phylogenetic diversity and vertical distribution of a halobacterial community in the atmosphere of an Asian dust (KOSA) source region, Dunhuang City.2008
Author(s)
Maki T, Susuki S, Kobayashi F, Kakikawa M, Yamada M, Higashi T, Chen B, Shi G, Hong C, Tobo Y, Hasegawa H, Ueda K, Iwasaka Y
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Journal Title
Air Quality Atmosphere and Health 1
Pages: 81-89
Related Report
Peer Reviewed
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[Journal Article] Phylogenetic analysis of atmospheric halotolerant bacterial communities at high altitude in an Asian dust (KOSA) arrival region
Author(s)
T. Maki, S. Susuki, F. Kobayashi, M. Kakikawa, Y. Tobo, M. Yamada, T. Higashi, A. Matsuki, C. Hong, H. Hasegawa, Y. Iwasaka
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Journal Title
Science of the Total Environment (in press)
Related Report
Peer Reviewed
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[Presentation] GSK3βによる膵がん細胞の増殖と浸潤の制御2009
Author(s)
北野綾子, 島崎猛夫, 東朋美, 近野祐里, 石垣靖人, 元雄良治, 宮本謙一, 川上和之, 源利成
Organizer
第20回 日本消化器癌発生学会総会
Place of Presentation
広島オリエンタルホテル(広島県)
Year and Date
2009-11-27
Related Report
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[Presentation] Direct sampling and identification of bioaerosols in the convective mixed layer over KOSA region, Dunhuang, using the separate culture.2008
Author(s)
Shi G, Kobayashi F, Toda S, Yamada M, Kakikawa M, Maki T, Higashi T, Hong C, Tobo Y, Chen B, Naganuma T, Iwasaka Y
Organizer
Proc of 5th International Workshop on Sand/ Duststorms and Associate Dustfall
Place of Presentation
Urumqi, Xinjiang, China
Related Report
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[Presentation] Halotolerant bacterial community survived in atmosphere of Asian dust (KOSA) source region, Dunhuang City.2008
Author(s)
Maki T, Susuki S, Kobayashi F, Kakikawa M, Yamada M, Higashi T, Hong C, Tobo Y, Hasegawa H, Ueda K, Iwasaka Y
Organizer
Proc of 5th International Workshop on Sand/ Duststorms and Associate Dustfall
Place of Presentation
Urumqi, Xinjiang, China
Related Report
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[Presentation] Dustborne microorganisms in KOSA source region, Dunhuang.2008
Author(s)
Kakikawa M, Kobayashi F, Maki T, Yamada M, Higashi T, Chen B, Shi G, Hong C, Tobo Y, Iwasaka Y
Organizer
Proc of 5th International Workshop on Sand/ Duststorms and Associate Dustfall
Place of Presentation
Urumqi, Xinjiang, China
Related Report