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Exploring the mechanism of rTMS therapeutic effects on writer's cramp

Research Project

Project/Area Number 20790615
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Neurology
Research InstitutionRitsumeikan University

Principal Investigator

URUSHIHARA Ryo  Ritsumeikan University, 産業社会学部, 准教授 (00398009)

Research Collaborator HOSONO Yuki  立命館大学, 共通教育推進機構, 嘱託講師 (40611538)
ASANUMA Koutaro  柳馬場武田リニック, 所長
KAJI Ryuji  徳島大学, ヘルスバイオサイエンス研究部, 教授 (00214304)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥130,000 (Direct Cost: ¥100,000、Indirect Cost: ¥30,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Keywords磁気刺激 / 書痙 / 体性感覚誘発電位
Research Abstract

Patient with writer's cramp can not take their pen in their hand well because of their involuntary movement. Repetitive transcranial magnetic stimulation (rTMS) is drawing attention as the non-invasive low-stressful procedure to Writer's cramp. However, the optimum conditions of rTMS to clinical application and its mechanism of therapeutic effects have not been well-known. The results of our present studies suggest that monophasic (phase) and 0.2Hz (frequency) are more effective than biphasic and 1Hz respectively in the case of stimulating on the premotor area, and also the possibility that the therapeutic effects of rTMS is derived from influencing the incoming somatosensory input for motor control.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (3 results)

All 2008

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (2 results)

  • [Journal Article] Comparison of monophasic versus biphasic stimulation in rTMS over premotor cortex.SEP and SPECT studies2008

    • Author(s)
      Yuki Hosono、Ryo Urushihara、Masafumi Harada、Naomi Morita、Nagako Murase、Yamato Kunikane、Hideki Shimazu、Kotaro Asanuma、Haruo Uguisu、Ryuji Kaji
    • Journal Title

      Clinical Neurophysiology 119(11)

      Pages: 2538-2545

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Presentation] 頻度の異なる単相性低頻度反復経頭蓋磁気刺激が書痙患者の体性感覚誘発電位に及ぼす影響2008

    • Author(s)
      漆原良、細野裕希、村瀬永子、島津秀紀、浅沼光太郎、梶龍兒
    • Organizer
      第38回日本臨床神経生理学会・学術大会
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Year and Date
      2008-11-14
    • Related Report
      2010 Final Research Report
  • [Presentation] 頻度の異なる単相性低頻度反復経頭蓋磁気刺激が書痙患者の体性感覚誘発電位に及ぼす影響2008

    • Author(s)
      漆原良
    • Organizer
      第38回日本臨床神経生理学会・学術大会
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2008-11-14
    • Related Report
      2008 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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