The protective effect of hydrogen on myocardial ischemia-reperfusion injury
| Project/Area Number |
20791082
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Anesthesiology/Resuscitation studies
|
|---|
| Research Institution | Oita University |
|---|
Principal Investigator |
KOGA Hironori Oita University, 医学部, 医員 (50468013)
|
|---|
| Project Period (FY) |
2008 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
|
|---|
| Keywords | 蘇生学 / 心筋虚血再灌流障害 / 水素 / 心筋虚血 / フリーラジカル / 電子スピン共鳴 |
|---|
| Research Abstract |
Recently, some researchers have reported that hydrogen gas has free radical scavenging effect, and they have been trying to apply hydrogen in a clinical setting as an antioxidant. In the present study, we have established methods of administering hydrogen to the body safely and appropriately, moreover, we have found that hydrogen ameliorates renal ischemia-reperfusion injury. These results have indicated that even low dose of hydrogen can produce an antioxidant effect, which has shown great potential for clinical use of hydrogen.
|
Report
(4 results)
Research Products
(8 results)
