| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2008: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
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| Research Abstract |
The preliminary AV shunt loop is known as the simplified method of vein graft, and has been widely performed in the microsurgical reconstruction. However, this method involves the risk of thrombosis due to turbulence. In the present study, an experimental model of the preliminary AV shunt model was created to investigate what has happened in the AV shunt loop. The result showed that turbulent flow is likely to occur in the AV shunt loop and the shear stress over 200 dyne/cm^2 act on the outer side of the loop vessel. Conclusion : Endothelium damage under a high shear stress and turbulent flow were thought to cause a high incidence of thrombosis and obstruction in the most distal part of AV shunt loop.
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