The molecular mechanism about the regeneration of the tooth using amphibian model.
| Project/Area Number |
20791345
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Morphological basic dentistry
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| Research Institution | The Nippon Dental University |
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Principal Investigator |
MIWA Yoko The Nippon Dental University, 生命歯学部, 講師 (80409218)
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| Project Period (FY) |
2008 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
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| Keywords | 口腔解剖学(含組織学・発生学) / 歯学 / 両生類 / 歯胚 / 血管 / 再生 / 免疫染色 / エナメル芽細 / 象牙芽細胞 / エナメル芽細胞 |
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| Research Abstract |
It is shown that the immunohistochemical localization of VEGF and its receptor and showed the specific expression pattern of VEGF and VEGF receptor in Cynops pyrrhogaster tooth development. It is postulated that the expression of VEGF in the inner enamel epithelium and odontoblast widely effects tooth development in newts, as well as in human and rodents.
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Report
(3 results)
Research Products
(6 results)
