| Project/Area Number |
20791484
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Dental engineering/Regenerative dentistry
|
|---|
| Research Institution | Asahi University |
|---|
Principal Investigator |
ITO Noriaki Asahi University, 歯学部, 助教 (40434500)
|
|---|
| Project Period (FY) |
2008 – 2009
|
| Project Status |
Completed (Fiscal Year 2009)
|
| Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2008: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
|
|---|
| Keywords | 低出力超音波 / 破骨細胞 / メカニカルストレス / 細胞骨格 / acid phosphatase 5, tartrate resistant / TNF receptor-associated factor 6 / Inositol 1,4,5-Triphosphate Receptor,Type3 / Cathepsin K / Inositol 1, 4, 5-Triphosohate Receotor, Type3 |
|---|
| Research Abstract |
Low-intensity pulsed ultrasound (LIPUS) stimulation, given as one of the mechanisms of osteoclast activity in rats is considered effects on the cytoskeleton. From the cytoskeleton and inhibit polymerization LIPUS stimulation. As a result, to re-polymerization of the cytoskeleton, LIPUS irradiated group was to promote the early re-polymerization than the non-irradiated group. This, LIPUS have shown that the morphological changes involved in cell stimulation, suggesting an association with mechanical stress. However, LIPUS that acts on any part of the cytoskeleton polymerization re-irradiation should be considered.
|
