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Relationship between periodontal condition and plasma/salivaoxidative stress

Research Project

Project/Area Number 20791641
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Social dentistry
Research InstitutionOkayama University

Principal Investigator

TAMAKI Naofumi  Okayama University, 大学院・医歯薬学総合研究科, 助教 (20335615)

Project Period (FY) 2008 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords歯周病 / 酸化ストレス / 抗酸化力 / 血漿 / 縦断研究 / 横断研究
Research Abstract

Twenty-two healthy non-smokers patients with chronic periodontitis and age- and gender- matched controls were recruited. Plasma levels of Oxidative-INEDX, oxLDL and C-reactive protein were measured at baseline, and at 1 and 2 months after non-surgical periodontal treatment. Periodontitis patients showed higher levels of circulating oxidative stress and oxLDL than healthy subjects. Non-surgical periodontal treatment was effective in decreasing oxLDL, which was positively associated with a reduction in circulating oxidative stress.

Report

(3 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • Research Products

    (13 results)

All 2010 2009 2008 Other

All Journal Article (6 results) (of which Peer Reviewed: 6 results) Presentation (4 results) Remarks (3 results)

  • [Journal Article] Short-term Effects of Non-surgical Periodontal Treatment on Plasma Level of Reactive Oxygen Metabolites in Chronic Periodontitis Patients2009

    • Author(s)
      Tamaki N、Tomofuji T、Ekuni D、Yamanaka R、Yamamoto T、Morita M
    • Journal Title

      J Periodontol 80巻6号

      Pages: 901-906

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Periodontitis and increase in circulating oxidative stress2009

    • Author(s)
      Tomofuji T、Irie K、Sanbe T、Azuma T、Ekuni D、Tamaki N、Yamamoto T、Morita M
    • Journal Title

      Japanese Dental Science Review 45巻

      Pages: 46-51

    • NAID

      10025820545

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Short-term Effects of Non-surgical Periodontal Treatment on Plasma Level of Reactive Oxygen Metabolites in Chronic Periodontitis Patients2009

    • Author(s)
      Naofumi Tamaki
    • Journal Title

      Journal of Periodontology 80

      Pages: 901906-901906

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Periodontitis and increase in circulating oxidative stress2009

    • Author(s)
      Takaaki Tomofuji
    • Journal Title

      Japanese Dental Science Review 45

      Pages: 4651-4651

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Relationship between Periodontal Condition and Plasma Reactive Oxygen Metabolites in Patients in the Maintenance Phase of Periodontal Treatment2008

    • Author(s)
      Tamaki N、Tomofuji T、Maruyama T、Ekuni D、Yamanaka R、Takeuchi N、Yamamoto T
    • Journal Title

      J Periodontol 79巻11号

      Pages: 2136-2142

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Relationship Between Periodontal Condition and Plasma Reactive Oxygen Metabolites in Patients in the Maintenance Phase of Periodontal Treatment2008

    • Author(s)
      Naofumi Tamaki
    • Journal Title

      Journal of Periodontology 79

      Pages: 2136-2142

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] 歯周病と酸化ストレス2010

    • Author(s)
      遠藤康正
    • Organizer
      第2回口腔環境制御研究
    • Place of Presentation
      長崎大学
    • Year and Date
      2010-02-10
    • Related Report
      2009 Final Research Report
  • [Presentation] 歯周病と酸化ストレス2010

    • Author(s)
      玉木直文
    • Organizer
      第2回「口腔環境制御研究」カテゴリー集会
    • Place of Presentation
      長崎
    • Year and Date
      2010-02-10
    • Related Report
      2009 Annual Research Report
  • [Presentation] Effect of non-surgical periodontal therapy on plasma reactive oxygen metabolites2008

    • Author(s)
      玉木直文
    • Organizer
      第56回Japanese Association for Dental Research
    • Place of Presentation
      名古屋
    • Year and Date
      2008-11-30
    • Related Report
      2009 Final Research Report
  • [Presentation] 歯周組織の状態と血漿の酸化ストレス度・抗酸化力との関係2008

    • Author(s)
      玉木直文
    • Organizer
      第51回日本歯周病学会春季学術大会
    • Place of Presentation
      大宮
    • Year and Date
      2008-04-26
    • Related Report
      2009 Final Research Report
  • [Remarks]

    • URL

      http://www.dent.okayama-u.ac.jp/yobou/index_sc_j.html

    • Related Report
      2009 Final Research Report
  • [Remarks]

    • URL

      http://www.dent.okayama-u.ac.jp/yobou/index_sc_j.html

    • Related Report
      2009 Annual Research Report
  • [Remarks]

    • URL

      http://www.dent.okayama-u.ac.jp/yobou/index_sc_j.html

    • Related Report
      2008 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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