Relationship between periodontal condition and plasma/salivaoxidative stress
| Project/Area Number |
20791641
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Social dentistry
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| Research Institution | Okayama University |
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Principal Investigator |
TAMAKI Naofumi Okayama University, 大学院・医歯薬学総合研究科, 助教 (20335615)
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| Project Period (FY) |
2008 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
|
| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 歯周病 / 酸化ストレス / 抗酸化力 / 血漿 / 縦断研究 / 横断研究 |
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| Research Abstract |
Twenty-two healthy non-smokers patients with chronic periodontitis and age- and gender- matched controls were recruited. Plasma levels of Oxidative-INEDX, oxLDL and C-reactive protein were measured at baseline, and at 1 and 2 months after non-surgical periodontal treatment. Periodontitis patients showed higher levels of circulating oxidative stress and oxLDL than healthy subjects. Non-surgical periodontal treatment was effective in decreasing oxLDL, which was positively associated with a reduction in circulating oxidative stress.
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Report
(3 results)
Research Products
(13 results)
