A basic study of periodontal tissues regeneration by periodontal ligament specific gene, "F-spondin".
| Project/Area Number |
20890245
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| Research Category |
Grant-in-Aid for Young Scientists (Start-up)
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| Allocation Type | Single-year Grants |
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| Research Field |
Periodontal dentistry
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| Research Institution | Matsumoto Dental University |
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Principal Investigator |
NISHIDA Eisaku Matsumoto Dental University, 歯学部, 助教 (10512519)
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| Project Period (FY) |
2008 – 2009
|
| Project Status |
Completed (Fiscal Year 2009)
|
| Budget Amount *help |
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 歯周病 / 歯根膜 / 創薬 / 再生 / 歯小嚢 |
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| Research Abstract |
F-spondin, a specific dental follicle cell gene can play a important role during periodontal ligament development via TGF-b. It became clear that F-spondin guided the type I collagen and type XII collagen expression of periodontal ligament cell by overexpression and knockdown experiment. Thus, F- spondin can control the form of the collagen matrix in the tooth development.
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Report
(3 results)
Research Products
(4 results)
