Investigation of habitat for Burkholderia gladioli pathovar cocovenenans and identification of its toxin gene

Research Project

Project/Area Number	20890247
Research Category	Grant-in-Aid for Young Scientists (Start-up)
Allocation Type	Single-year Grants
Research Field	Hygiene
Research Institution	Aichi Gakuin University
Principal Investigator	TOMIDA Junko Aichi Gakuin University, 薬学部, 助教 (10454323)
Project Period (FY)	2008 – 2009
Project Status	Completed (Fiscal Year 2009)
Budget Amount *help	¥3,302,000 (Direct Cost: ¥2,540,000、Indirect Cost: ¥762,000) Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000) Fiscal Year 2008: ¥1,742,000 (Direct Cost: ¥1,340,000、Indirect Cost: ¥402,000)
Keywords	毒素 / 食中毒 / 生息調査 / Bongkrekic acid / Toxoflavin / BA毒素
Research Abstract	In order to grasp the habitation of Burkholderia gladioli pathovar cocovenenans in Japan, observations were carried out in agricultural environment. A few strains isolated from rice plant seeding produced Bongkrekic acid. When ether-extracted toxin was adoministrated orally to mice, the mice died subacutely and its stomachs were markedly-distended. The toxin may affect gastric motility.