電気インピーダンスによる流路内の血球検査とマラリア検出への応用
| Project/Area Number |
20J10046
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| Research Category |
Grant-in-Aid for JSPS Fellows
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| Allocation Type | Single-year Grants |
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| Section | 国内 |
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| Review Section |
Basic Section 90110:Biomedical engineering-related
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| Research Institution | Chiba University |
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Principal Investigator |
TRAN ANH KIET 千葉大学, 融合理工学府, 特別研究員(DC2)
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| Project Period (FY) |
2020-04-24 – 2022-03-31
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| Project Status |
Completed (Fiscal Year 2021)
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| Budget Amount *help |
¥1,700,000 (Direct Cost: ¥1,700,000)
Fiscal Year 2021: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 2020: ¥900,000 (Direct Cost: ¥900,000)
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| Keywords | Malaria / EIS / Single cell / Lung diseases |
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| Outline of Research at the Start |
This technology once successful will see prompt detection of malaria parasite at a very early stage before clinical manifestation and support the necessary health care infrastructure. Particularly, the device will be improved and developed into a simple wrist bands which will be equipped for children and elderly people for early detection of the aforementioned infection.
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| Outline of Annual Research Achievements |
The study concentrated on intense analytical validation with a lab on chip CD type EIS hardware which was made in year 2020 in Takei lab by using malaria parasite-infected primates conducted in collaboration with Chiba University Hospital further limited field testing at Chiba University Hospital in Japan. For this reason, the humanized mouse, which is less costly and more conv enient to maintain, was used for in vitro test. The mouse is infected by injection the parasite P.falciparum into blood stream via an intravenous route because the intravenous route is stable and ensure the long-lasting presence of parasite within the mouse host. Moreover, the parasite can reach 10% of concentration by adding new parasite intravenously every 2 or 3 days. Then the we ll-prepared blood of mouse was tested by the new a lab on chip CD type EIS hardware under different conditions. This technology once successful will see prompt detection of malaria parasite at a very early stage.
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| Research Progress Status |
令和3年度が最終年度であるため、記入しない。
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| Strategy for Future Research Activity |
令和3年度が最終年度であるため、記入しない。
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Report
(2 results)
Research Products
(6 results)
