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Development of novel spectroscopic imaging for diagnostics of retinal function

Research Project

Project/Area Number 21200019
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)

Allocation TypeSingle-year Grants
Research Field Biomedical engineering/Biological material science
Measurement engineering
Research InstitutionKyushu University

Principal Investigator

NAKAMURA Daisuke  九州大学, システム情報科学研究院, 准教授 (40444864)

Co-Investigator(Kenkyū-buntansha) YOSHINAGA Yukiyasu  九州大学, 芸術工学研究院, 助教 (60304854)
ENAIDA Hiroshi  九州大学, 医学研究院, 講師 (00363333)
Co-Investigator(Renkei-kenkyūsha) OKADA Tatsuo  九州大学, システム情報科学研究院, 教授 (90127994)
ISHIBASHI Tatsuro  九州大学, 医学研究院, 教授 (30150428)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥27,950,000 (Direct Cost: ¥21,500,000、Indirect Cost: ¥6,450,000)
Fiscal Year 2011: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
Fiscal Year 2010: ¥10,010,000 (Direct Cost: ¥7,700,000、Indirect Cost: ¥2,310,000)
Fiscal Year 2009: ¥10,920,000 (Direct Cost: ¥8,400,000、Indirect Cost: ¥2,520,000)
Keywords分光イメージング / 酸素飽和度 / 非侵襲計測 / 眼底網膜機能 / 眼底綱膜機能
Research Abstract

Oxygen saturation imaging of human retinal vessels based on the spectroscopic technique was proposed for early diagnostics of retinal diseases and disorders. Retinal arteries and veins were clearly distinguished by the imaging technique. Furthermore, a high resolution imaging equipment was developed for analyzing the retinal capillary vessel.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (32 results)

All 2011 2010 2009 2006

All Journal Article (10 results) (of which Peer Reviewed: 4 results) Presentation (20 results) Patent(Industrial Property Rights) (2 results)

  • [Journal Article] 2 波長分光分析を用いた網膜血管酸素飽和度計測の評価2011

    • Author(s)
      吉永幸靖, 中村大輔, 岡田龍雄, 江内田寛, 石橋達朗
    • Journal Title

      電子情報通信学会技術研究報告

      Volume: 111 Pages: 441-441

    • NAID

      10031093841

    • Related Report
      2011 Final Research Report
  • [Journal Article] Spectroscopic Imaging of Oxygen Saturation Level in Retinal Capillary Vessels Area2011

    • Author(s)
      S. Shibasato, K. Tatsuguchi, D. Nakamura, T. Okada, Y. Yoshinaga, H. Enaida, T. Ishibashi
    • Journal Title

      Proc. CLEO Pacific Rim 2011

      Volume: 4250-CT-6

    • Related Report
      2011 Final Research Report
  • [Journal Article] 糖尿病網膜症の病態と最近の治療2011

    • Author(s)
      江内田寛, 石橋達朗
    • Journal Title

      Diabetes Journal.

      Volume: 39 Pages: 115-115

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Spectroscopic Imaging of Oxygen Saturation Level in Retinal Capillary Vessels Area2011

    • Author(s)
      S.Shibasato, K.Tatsuguchi, D.Nakamura, T.Okada, Y.Yoshinaga, H.Enaida, T.Ishibashi
    • Journal Title

      Proc.IQEC/CLEO Pacific Rim 2011

    • Related Report
      2011 Annual Research Report
  • [Journal Article] 2波長分光分析を用いた網膜血管酸素飽和度計測の評価2011

    • Author(s)
      吉永幸靖, 中村大輔, 岡田龍雄, 江内田寛, 石橋達朗
    • Journal Title

      電子情報通信学会技術研究報告

      Volume: 111 Pages: 441-444

    • NAID

      10031093841

    • Related Report
      2011 Annual Research Report
  • [Journal Article] 糖尿病網膜症の病態と最近の治療2011

    • Author(s)
      江内田寛, 石橋達朗
    • Journal Title

      Diabetes Journal

      Volume: 39 Pages: 115-120

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Visualization of Oxygen Saturation Level in Retinal Capillary Vessels by Spectroscopic Imaging2010

    • Author(s)
      K.Tatsuguchi, N.Matsuoka, D.Nakamura, T.Okada, Y.Yoshinaga, H.Enaida, T.Ishibashi
    • Journal Title

      The 7th Asia-Pacific Laser Symposium

      Pages: 221-221

    • Related Report
      2010 Annual Research Report
  • [Journal Article] Spectroscopic imaging of oxygen saturation level in retinal capillary vessels area2010

    • Author(s)
      K.Tatsuguchi, S.Shibasato, D.Nakamura, T.Okada, Y.Yoshinaga, H.Enaida, T.Ishibashi
    • Journal Title

      Proc.IEEE Region 10 Conference 2010

      Pages: 1478-1480

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Oxygen Saturation lmaging of Human Retinal Vessels and Measurement in Eye Disease Patient for Clinical Application2010

    • Author(s)
      D.Nakamura, N.Matsuoka, K.Tatsuguchi, M.Ogata, Y.Yoshinaga, H.Enaida, T.Okada, T.lshibashi
    • Journal Title

      SPIE 7550

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Development of Oxygen Saturation Leve1 Measurement Method of Retinal Blood Vessels by Spectroscopic lmaging2009

    • Author(s)
      N.Matsuoka, K.Tatsuguchi, M.Ogata, D.Nakamura, Y.Yoshinaga, H.Enaida, T.Okada, T.Ishibashi
    • Journal Title

      Proc.of CLEO Pacific Rim 2009

    • Related Report
      2009 Annual Research Report
  • [Presentation] 臨床に直結する研究開発を目指して~連携研究の実践~2011

    • Author(s)
      江内田寛
    • Organizer
      第2回福島県眼科臨床セミナー
    • Place of Presentation
      郡山市,福島県
    • Year and Date
      2011-09-03
    • Related Report
      2011 Annual Research Report
  • [Presentation] Spectroscopic Imaging of Oxygen Saturation Level in Retinal Capillary Vessels Area2011

    • Author(s)
      S. Shibasato, K. Tatsuguchi, D. Nakamura, T. Okada, Y. Yoshinaga, H. Enaida, T. Ishibashi
    • Organizer
      CLEO Pacific Rim 2011
    • Place of Presentation
      Sydney, Australia
    • Year and Date
      2011-08-31
    • Related Report
      2011 Final Research Report
  • [Presentation] Spectroscopic Imaging of Oxygen Saturation Level in Retinal Capillary Vessels Area2011

    • Author(s)
      S.Shibasato, K.Tatsuguchi, D.Nakamura, T.Okada, Y.Yoshinaga, H.Enaida, T.Ishibashi
    • Organizer
      IQEC/CLEO Pacific Rim 2011
    • Place of Presentation
      Sydney, Australia
    • Year and Date
      2011-08-31
    • Related Report
      2011 Annual Research Report
  • [Presentation] 分光イメージングを利用した眼底機能計測2011

    • Author(s)
      中村大輔, 竜口賢一, 柴里秀平, 吉永幸靖, 江内田寛, 岡田龍雄, 石橋達朗
    • Organizer
      レーザー学会学術講演会
    • Place of Presentation
      電気通信大学(東京都)
    • Year and Date
      2011-01-09
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] 分光イメージングによる眼底血管酸素飽和度の可視化と信頼性の検証2010

    • Author(s)
      柴里秀平, 竜口賢一, 中村大輔, 岡田龍雄, 吉永幸靖, 江内田寛, 石橋達朗
    • Organizer
      平成22年度応用物理学会九州支部学術講演会
    • Place of Presentation
      九州大学(福岡県)
    • Year and Date
      2010-11-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] Spectroscopic imaging of oxygen saturation level in retinal capillary vessels area2010

    • Author(s)
      K. Tatsuguchi, S. Shibasato, D. Nakamura, T. Okada, Y. Yoshinaga, H. Enaida, T. Ishibashi
    • Organizer
      IEEE Region 10 Conference 2010
    • Place of Presentation
      国際会議場(福岡県)
    • Year and Date
      2010-11-24
    • Related Report
      2011 Final Research Report
  • [Presentation] Spectroscopic imaging of oxygen saturation level in retinal capillary vessels area2010

    • Author(s)
      K.Tatsuguchi, S.Shibasato, D.Nakamura, T.Okada, Y.Yoshinaga, H.Enaida, T.Ishibashi
    • Organizer
      Proc.IEEE Region 10 Conference 2010
    • Place of Presentation
      国際会議場(福岡県)
    • Year and Date
      2010-11-24
    • Related Report
      2010 Annual Research Report
  • [Presentation] 分光イメージングによる眼底毛細血管領域の酸素飽和度測定2010

    • Author(s)
      竜口賢一, 柴里秀平, 中村大輔, 吉永幸靖, 江内田寛, 岡田龍雄, 石橋達朗
    • Organizer
      第63回電気関係学会九州支部連合大会
    • Place of Presentation
      九州産業大学(福岡県)
    • Year and Date
      2010-09-26
    • Related Report
      2010 Annual Research Report
  • [Presentation] 分光イメージングを用いた眼底網膜機能診断技術の開発2010

    • Author(s)
      中村大輔, 竜口賢一, 柴里秀平, 吉永幸靖, 江内田寛, 岡田龍雄, 石橋達朗
    • Organizer
      電気学会 電子・情報・システム部門大会
    • Place of Presentation
      熊本大学(熊本県)
    • Year and Date
      2010-09-02
    • Related Report
      2010 Annual Research Report
  • [Presentation] Visualization of Oxygen Saturation Level in Retinal Capillary Vessels by Spectroscopic Imaging2010

    • Author(s)
      K.Tatsuguchi, N.Matsuoka D.Nakamura, T.Okada, Y.Yoshinaga, H.Enaida, T.Ishibashi
    • Organizer
      The 7th Asia-Pacific Laser Symposium
    • Place of Presentation
      Seogwipo KAL Hotel(韓国)
    • Year and Date
      2010-05-14
    • Related Report
      2010 Annual Research Report
  • [Presentation] 分光イメージングによる眼底毛細血管領域の酸素飽和度の可視化2010

    • Author(s)
      竜口賢一, 松岡昇, 中村大輔, 岡田龍雄, 吉永幸靖, 江内田寛, 石橋達朗
    • Organizer
      応用物理学関係連合講演会
    • Place of Presentation
      東海大学(神奈川)
    • Year and Date
      2010-03-19
    • Related Report
      2009 Annual Research Report
  • [Presentation] 眼底網膜機能診断のための分光イメージング2010

    • Author(s)
      中村大輔, 松岡昇, 竜口賢一, 岡田龍雄, 吉永幸靖, 江内田寛, 石橋達朗
    • Organizer
      レーザー学会学術講演会
    • Place of Presentation
      大阪
    • Year and Date
      2010-02-04
    • Related Report
      2009 Annual Research Report
  • [Presentation] Oxygen saturation imaging of human retinal vessels and measurement in eye disease patient for clinical application2010

    • Author(s)
      D.Nakamura, N.Matsuoka, K.Tatsuguchi, M.Ogata, Y.Yoshinaga, H.Enaida, T.Okada, T.lshibashi
    • Organizer
      SPIE Photonics West 2010
    • Place of Presentation
      アメリカ・サンフランシスコ
    • Year and Date
      2010-01-25
    • Related Report
      2009 Annual Research Report
  • [Presentation] 分光イメージングによる眼底血中酸素飽和度計測2009

    • Author(s)
      尾形学, 松岡昇, 竜口賢一, 高橋昭彦, 中村大輔, 岡田龍雄, 吉永幸靖, 江内田寛, 石橋達朗
    • Organizer
      日本レーザー医学会総会
    • Place of Presentation
      東京
    • Year and Date
      2009-12-02
    • Related Report
      2009 Annual Research Report
  • [Presentation] 分光イメージングによる眼底血管酸素飽和度の可視化と臨床への応用2009

    • Author(s)
      竜口賢一, 松岡昇, 高橋昭彦, 中村大輔, 岡田龍雄, 吉永幸靖, 江内田寛, 石橋達朗
    • Organizer
      応用物理学会九州支部学術講演会
    • Place of Presentation
      熊本大学
    • Year and Date
      2009-11-21
    • Related Report
      2009 Annual Research Report
  • [Presentation] 分光イメージングによるリアルタイム眼底血管酸素飽和度測定装置の開発と臨床応用2009

    • Author(s)
      松岡昇, 竜口賢一, 尾形学, 中村大輔, 岡田龍雄, 吉永幸靖, 江内田寛, 石橋達朗
    • Organizer
      電気関係学会九州支部連合大会
    • Place of Presentation
      飯塚
    • Year and Date
      2009-09-28
    • Related Report
      2009 Annual Research Report
  • [Presentation] 分光イメージングを利用した眼底機能計測2009

    • Author(s)
      中村大輔, 松岡昇, 竜口賢一, 岡田龍雄, 吉永幸靖, 江内田寛, 石橋達朗
    • Organizer
      レーザー学会研究会
    • Place of Presentation
      宮崎
    • Year and Date
      2009-09-14
    • Related Report
      2009 Annual Research Report
  • [Presentation] 眼底網膜機能の可視化診断のための分光イメージング装置の開発2009

    • Author(s)
      中村大輔, 松岡昇, 竜口賢一, 岡田龍雄, 吉永幸靖, 江内田寛, 石橋達朗
    • Organizer
      応用物理学会学術講演会
    • Place of Presentation
      富山大学
    • Year and Date
      2009-09-08
    • Related Report
      2009 Annual Research Report
  • [Presentation] Development of Oxygen Saturation Leve1 Measurement Method of Retinal Blood Vessels by Spectroscopic lmaging2009

    • Author(s)
      N.Matsuoka, K.Tatsuguchi, M.Ogata, D.Nakamura, Y.Yoshinaga, H.Enaida, T.Okada, T.lshibashi
    • Organizer
      CLEO Pacific Rim 2009
    • Place of Presentation
      中国・上海
    • Year and Date
      2009-08-31
    • Related Report
      2009 Annual Research Report
  • [Presentation] 2波長分光イメージングによる眼底血中酸素飽和度の可視化2009

    • Author(s)
      中村大輔, 松岡昇, 末田聡, 岡田龍雄, 吉永幸靖, 江内田寛, 石橋達朗
    • Organizer
      応用物理学関係連合講演会
    • Place of Presentation
      筑波大学(茨城)
    • Year and Date
      2009-04-01
    • Related Report
      2009 Annual Research Report
  • [Patent(Industrial Property Rights)] 血管情報分析装置及び生活習慣病因子検査方法2006

    • Inventor(s)
      砂田向壱, 石橋達朗, 源田悦夫, 竹田仰, 岡田龍雄, 吉永幸靖, 江内田寛, 館眞利
    • Industrial Property Rights Holder
      砂田向壱, 石橋達朗, 源田悦夫, 竹田仰, 岡田龍雄, 吉永幸靖, 江内田寛, 館眞利
    • Filing Date
      2006-12-11
    • Related Report
      2011 Final Research Report
  • [Patent(Industrial Property Rights)] 異方性ノイズを除去するためのプログラムと異方性ノイズ除去方法2006

    • Inventor(s)
      吉永幸靖, 砂田向壱, 石橋達朗, 源田悦夫, 竹田仰, 岡田龍雄, 江内田寛, 館眞利
    • Industrial Property Rights Holder
      吉永幸靖, 砂田向壱, 石橋達朗, 源田悦夫, 竹田仰, 岡田龍雄, 江内田寛, 館眞利
    • Filing Date
      2006-12-11
    • Related Report
      2011 Final Research Report

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Published: 2009-04-01   Modified: 2018-03-28  

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