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Elucidation of biofilm formation and its control technology

Research Project

Project/Area Number 21241022
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Environmental technology/Environmental materials
Research InstitutionOsaka Prefecture University

Principal Investigator

NOMURA Toshiyuki  大阪府立大学, 大学院・工学研究科, 准教授 (00285305)

Co-Investigator(Kenkyū-buntansha) SUGIOKA Kenichi  東北大学, 大学院・工学研究科, 助教 (80438233)
TOKUMOTO Hayato  大阪府立大学, 大学院・工学研究科, 助教 (70405348)
KINOSHITA Takuya  大阪府立大学, 大学院・工学研究科, 助教 (90453141)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥40,040,000 (Direct Cost: ¥30,800,000、Indirect Cost: ¥9,240,000)
Fiscal Year 2011: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
Fiscal Year 2010: ¥19,110,000 (Direct Cost: ¥14,700,000、Indirect Cost: ¥4,410,000)
Fiscal Year 2009: ¥14,690,000 (Direct Cost: ¥11,300,000、Indirect Cost: ¥3,390,000)
Keywordsバイオフィルム / 相互作用 / 付着力 / 帯電性 / 疎水性 / 磁性粒子
Research Abstract

In this research, elucidation of biofilm formation and development of its control technology were attempted. As a result, it was found that the pattern of biofilm formation depended on the change of free energy of interaction when a microbial cell adheres to a solid surface. Moreover, it was clarified that the magnetic particle adsorbed degradative enzyme fixed on the place where the biofilm was formed easily in the flow field using the magnetic field preliminarily could inhibit the biofilm formation.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (42 results)

All 2012 2011 2010 2009 Other

All Journal Article (10 results) (of which Peer Reviewed: 10 results) Presentation (26 results) Book (2 results) Patent(Industrial Property Rights) (4 results)

  • [Journal Article] 酢酸資化性メタン生成菌の付着・凝集特性の評価2012

    • Author(s)
      野村俊之, 吉原章仙, 徳本勇人, 小西康裕
    • Journal Title

      粉体工学会誌

      Volume: 49 Pages: 260-265

    • NAID

      10030575659

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Novel anaerobic digestion induced by bacterial components for value-added byproducts from high-loading glycerol2012

    • Author(s)
      H. Tokumoto, M. Tanaka
    • Journal Title

      Bioresource Technology

      Volume: 107 Pages: 327-332

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] PSLナノ粒子が大腸菌に及ぼす環境毒性評価2012

    • Author(s)
      宮本顕久, 徳本勇人, 小西康裕, 野村俊之
    • Journal Title

      粉体工学会誌

      Volume: 5(印刷中)

    • NAID

      10030764840

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 酸生成菌共存下での酢酸資化性メタン生成菌の付着・凝集挙動2012

    • Author(s)
      野村俊之, 吉原章仙, 徳本勇人, 小西康裕
    • Journal Title

      粉体工学会誌

      Volume: 7(印刷中)

    • NAID

      10030834923

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The Role of Microbial Surface Properties and Extracellular Polymer in Lactococcus Lactis Aggregation, Adv2009

    • Author(s)
      T. Nomura, H. Narahara, H. Tokumoto, Y. Konishi
    • Journal Title

      Powder Technol

      Volume: 20 Pages: 537-541

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] 一様な脈動流中の球形固体粒子に働く抗力の評価2009

    • Author(s)
      杉岡健一, 見上信, 塚田隆夫, 小森悟
    • Journal Title

      日本機械学会論文集B編

      Volume: 75 Pages: 2128-2134

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] The Role of Microbial Surface Properties and Extracellular Polymer in Lactococcus Lactis Aggregation2009

    • Author(s)
      T.Nomura, H.Narahara, H.Tokumoto, Y.Konishi
    • Journal Title

      Advanced Powder Technology 20

      Pages: 537-541

    • NAID

      10027275645

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 一様な脈動流中の球形固体粒子に働く抗力の評価2009

    • Author(s)
      杉岡健一、見上信、塚田隆夫、小森悟
    • Journal Title

      日本機械学会論文集B編 75

      Pages: 2128-2134

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 酸生成菌共存下での酢酸資化性メタン生成菌の付着・凝集挙動

    • Author(s)
      野村俊之, 吉原章仙, 徳本勇人, 小西康裕
    • Journal Title

      粉体工学会誌

      Volume: (印刷中)

    • NAID

      10030834923

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] PSLナノ粒子が大腸菌に及ぼす環境毒性評価

    • Author(s)
      宮本顕久, 徳本勇人, 小西康裕, 野村俊之
    • Journal Title

      粉体工学会誌

      Volume: (印刷中)

    • NAID

      10030764840

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Presentation] 廃グリセリンと下水汚泥を同時に処理する新規嫌気発酵プロセスの構築2011

    • Author(s)
      木村知恵、徳本勇人
    • Organizer
      廃棄物資源循環学会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-05
    • Related Report
      2011 Annual Research Report
  • [Presentation] 微生物の界面付着現象のコロイド科学的検討2011

    • Author(s)
      野村俊之, 宮崎準平, 延平典隆, 矢野哲司, 楢原久哉, 小西康裕
    • Organizer
      2011年度粉体工学会秋期研究発表会
    • Place of Presentation
      大阪
    • Year and Date
      2011-10-19
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 嫌気発酵を用いた過負荷グリセリン分解の促進と制御技術の開発2011

    • Author(s)
      柏木麻衣、徳本勇人
    • Organizer
      日本生物工学会
    • Place of Presentation
      東京
    • Year and Date
      2011-09-28
    • Related Report
      2011 Annual Research Report
  • [Presentation] Synthesis of gold/iron-oxide composite nanoparticles and adsorption of bovine serum albumin on particle surface2011

    • Author(s)
      T. Tani, S. Watanabe, T. Kinoshita, M. Adachi
    • Organizer
      6th Asia Pacific Chemical Reaction Engineering Symposium
    • Place of Presentation
      北京,中国
    • Year and Date
      2011-09-20
    • Related Report
      2011 Final Research Report
  • [Presentation] Synthesis of gold/iron-oxide composite nanoparticles and adsorption of bovine serum albumin on particle surface2011

    • Author(s)
      T.Tani, S.Watanabe, T.Kinoshita, M.Adachi
    • Organizer
      6th Asia Pacific Chemical Reaction Engineering Symposium
    • Place of Presentation
      北京、中国
    • Year and Date
      2011-09-20
    • Related Report
      2011 Annual Research Report
  • [Presentation] Synthesis of gold/iron-oxide composite nanop articles by liquid laser ablation for biomedical applications2011

    • Author(s)
      M.Nama, T.Kinoshita, M.Adcahi
    • Organizer
      6th Asia Pacific Chemical Reaction Engineering Symposium
    • Place of Presentation
      北京、中国
    • Year and Date
      2011-09-20
    • Related Report
      2011 Annual Research Report
  • [Presentation] 液相レーザーアブレーションによる金/酸化鉄磁性複合ナノ粒子の合成2011

    • Author(s)
      名間瑞樹, 木下卓也, 足立元明
    • Organizer
      化学工学会第43回秋季大会
    • Place of Presentation
      名古屋工業大学
    • Year and Date
      2011-09-14
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] バイオフィルムの形成と酵素による分解の三次元評価2011

    • Author(s)
      宮崎準平, 矢野哲司, 小西康裕, 野村俊之
    • Organizer
      化学工学会第43回秋季大会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-09-14
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] バイオ分野での応用に向けた金酸化鉄複合ナノ粒子の合成2011

    • Author(s)
      渡邊周二, 谷俊之, 木下卓也, 足立元明
    • Organizer
      化学工学会第43回秋季大会
    • Place of Presentation
      名古屋工業大学
    • Year and Date
      2011-09-14
    • Related Report
      2011 Annual Research Report
  • [Presentation] 金/酸化鉄磁性複合ナノ粒子へのBSAたんぱく質の吸着量の評価2011

    • Author(s)
      谷俊之, 渡邊周二, 木下卓也, 足立元明
    • Organizer
      化学工学会第43回秋季大会
    • Place of Presentation
      名古屋工業大学
    • Year and Date
      2011-09-14
    • Related Report
      2011 Annual Research Report
  • [Presentation] 微生物の付着現象の解明とその利用技術の開発2011

    • Author(s)
      野村俊之
    • Organizer
      第63回コロイドおよび界面化学討論会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-08
    • Related Report
      2011 Final Research Report
  • [Presentation] 微生物の付着現象の解明とその利用技術の開発2011

    • Author(s)
      野村俊之
    • Organizer
      第63回コロイドおよび界面化学討論会
    • Place of Presentation
      京都(招待講演)
    • Year and Date
      2011-09-08
    • Related Report
      2011 Annual Research Report
  • [Presentation] 超音波噴霧熱分解法による金酸化鉄複合ナノ粒子の合成2011

    • Author(s)
      渡邊周二, 谷俊之, 木下卓也, 足立元明
    • Organizer
      第28回エアロゾル科学・技術研究討論会
    • Place of Presentation
      大阪府立大学
    • Year and Date
      2011-08-29
    • Related Report
      2011 Annual Research Report
  • [Presentation] 下水汚泥と廃グリセリンを同時に処理する新規嫌気発酵プロセスの構築2011

    • Author(s)
      木村知恵、徳本勇人
    • Organizer
      環境バイテクノロジー学会
    • Place of Presentation
      東京
    • Year and Date
      2011-06-20
    • Related Report
      2011 Annual Research Report
  • [Presentation] 微生物の付着現象における細胞外ポリマーと運動性の役割2011

    • Author(s)
      宮崎準平, 矢野哲司, 野村俊之, 小西康裕
    • Organizer
      2011年度粉体工学会春期研究発表会
    • Place of Presentation
      東京
    • Year and Date
      2011-05-24
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] ポリマー被覆型複合磁性微粒子の合成2011

    • Author(s)
      木下卓也, 小坂康平, 谷俊之, 足立元明
    • Organizer
      化学工学会第76年会
    • Place of Presentation
      東京農工大学
    • Year and Date
      2011-03-22
    • Related Report
      2011 Final Research Report
  • [Presentation] ポリマー被覆型複合磁性微粒子の合成2011

    • Author(s)
      木下卓也, 小坂康平, 谷俊之, 足立元明
    • Organizer
      化学工学会 第76年会
    • Place of Presentation
      東京農工大学
    • Year and Date
      2011-03-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] 噴霧熱分解法による金/酸化鉄磁性複合ナノ粒子の合成2011

    • Author(s)
      渡邊周二, 木下卓也, 足立元明
    • Organizer
      第13回化学工学会学生発表会
    • Place of Presentation
      神戸大学
    • Year and Date
      2011-03-05
    • Related Report
      2010 Annual Research Report
  • [Presentation] 微粒子工学から微生物工学へ2010

    • Author(s)
      野村俊之
    • Organizer
      2010年度秋期研究発表会
    • Place of Presentation
      東京ビックサイト
    • Year and Date
      2010-11-30
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] 大腸菌-ガラス表面間に働く付着力の評価2010

    • Author(s)
      矢野哲司, 楢原久哉, 野村俊之, 小西康裕
    • Organizer
      第46回粉体工学会夏期シンポジウム
    • Place of Presentation
      関西セミナーハウス
    • Year and Date
      2010-08-09
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] Estimation of Adhesive Force between a Biological Cell and a Glass Surface2009

    • Author(s)
      T. Nomura
    • Organizer
      35th APHS Seminar : Young Researchers Meeting 2009 in UK
    • Place of Presentation
      York, UK
    • Year and Date
      2009-12-16
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Presentation] Synthesis of highly-dispersive gold/iron-oxide magnetic nanoparticles2009

    • Author(s)
      Y. Fujikawa, M. Yoshikawa, T. Kinoshita, M. Adachi, S. Seino, T. A. Yamamoto
    • Organizer
      2009 MRS FALL MEETING
    • Place of Presentation
      Boston, USA
    • Year and Date
      2009-12-01
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Presentation] 微生物-ガラス表面間に働く付着力の評価2009

    • Author(s)
      矢野哲司, 楢原久哉, 野村俊之, 小西康裕
    • Organizer
      第41回化学工学会秋季大会
    • Place of Presentation
      広島大学
    • Year and Date
      2009-09-17
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Presentation] バイオ応用を目指した金/磁性酸化鉄複合ナノ粒子の合成2009

    • Author(s)
      木下卓也, 藤川祐喜, 吉川基宏, 足立元明, 清野智史, 山本孝夫
    • Organizer
      第26回エアロゾル科学・技術研究討論会
    • Place of Presentation
      岡山大学
    • Year and Date
      2009-08-19
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Presentation] Glycerol Based Novel Hydrogen and Methane Fermentation Processes2009

    • Author(s)
      H. Tokumoto, M. Tanaka, H. Yoshida
    • Organizer
      The 1st Korea-Japan International Symposium on Microbial Ecology
    • Place of Presentation
      Jeju, Korea
    • Year and Date
      2009-05-29
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Presentation] Effect of surface properties of acetate-utilizing methanogens on anaerobic granulation2009

    • Author(s)
      T. Nomura, A. Yoshihara, Y. Konishi
    • Organizer
      The 1st Korea-Japan International Symposium on Microbial Ecology
    • Place of Presentation
      Jeju, Korea
    • Year and Date
      2009-05-29
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Book] 社会との垣根を越える大学の挑戦2011

    • Author(s)
      徳本勇人
    • Publisher
      株式会社エヌ・ティー・エス
    • Related Report
      2011 Final Research Report
  • [Book] 社会との垣根を越える大学の挑戦2011

    • Author(s)
      徳本勇人(分担)
    • Total Pages
      343
    • Publisher
      株式会社エヌ・ティー・エス
    • Related Report
      2011 Annual Research Report
  • [Patent(Industrial Property Rights)] グリセリンの処理方法2010

    • Inventor(s)
      徳本勇人,井口太輔,田中雅浩
    • Industrial Property Rights Holder
      大阪府立大学
    • Filing Date
      2010-08-23
    • Related Report
      2011 Final Research Report
  • [Patent(Industrial Property Rights)] グリセリンの処理方法および下水余剰汚泥の処理方法2010

    • Inventor(s)
      徳本勇人,木村知恵
    • Industrial Property Rights Holder
      大阪府立大学
    • Filing Date
      2010-08-17
    • Related Report
      2011 Final Research Report
  • [Patent(Industrial Property Rights)] グリセリンの処理方法2010

    • Inventor(s)
      徳本勇人, 井口太輔, 田中雅浩
    • Industrial Property Rights Holder
      大阪府立大学
    • Industrial Property Number
      2010-186025
    • Filing Date
      2010-08-23
    • Related Report
      2010 Annual Research Report
  • [Patent(Industrial Property Rights)] グリセリンの処理方法および下水余剰汚泥の処理方法2010

    • Inventor(s)
      徳本勇人, 木村知恵
    • Industrial Property Rights Holder
      大阪府立大学
    • Industrial Property Number
      2010-182642
    • Filing Date
      2010-08-17
    • Related Report
      2010 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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