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Development of Diagnostic and Therapeutic Support System based on Novel Brain Atlas with Morphological, Functional and Pathological Information

Research Project

Project/Area Number 21300185
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Medical systems
Research InstitutionThe University of Tokyo

Principal Investigator

MASUTANI Yoshitaka  東京大学, 医学部附属病院, 講師 (20345193)

Co-Investigator(Renkei-kenkyūsha) HAYASHI Naoto  東京大学, 医学部附属病院, 特任准教授 (10261992)
SUZUKI Yuichi  東京大学, 医学部附属病院, 放射線技師 (70420221)
ABE Osamu  日本大学, 医学部付属病院, 教授 (50302716)
KAMADA Kyousuke  旭川医科大学, 医学部付属病院, 教授 (80372374)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥11,180,000 (Direct Cost: ¥8,600,000、Indirect Cost: ¥2,580,000)
Fiscal Year 2011: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2010: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2009: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Keywords検査診断システム / 脳アトラス / 治療支援 / 検査・診断システム
Research Abstract

In this study, we aimed at construction of an "integrated brain atlas" as a standard brain map consisting of morphological, functional and pathological information of brain, and its application to diagnosis and therapy. We developed various techniques and systems for MR imaging, image processing and display for diagnostic support, surgical navigation. As a result, we achieved an integrate atlas of multivariate map including biological diffusional information, and completed systems for diagnostic and therapeutic aid, and performed preliminary experiments.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (35 results)

All 2012 2011 2010 2009 Other

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Presentation (28 results) Book (2 results) Remarks (1 results)

  • [Journal Article] Motion-robust diffusion tensor acquisition at routine 3T magnetic resonance imaging2010

    • Author(s)
      Hasina Yasmin, Hiroyuki Kabasawa, Shigeki Aoki, Osamu Abe, Yoshitaka Masutani, Naoto Hayashi and Kuni Ohtomo
    • Journal Title

      Japanese journal of radiology

      Volume: 28 Pages: 27-33

    • NAID

      50007467428

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] CIRCUS : An MDA platform for clinical image analysis in hospitals2010

    • Author(s)
      Yukihiro Nomura, Naoto Hayashi, Yoshitaka Masutani, Takeharu Yoshikawa, Mitsutaka Nemoto, Shohei Hanaoka, Soichiro Miki, Eriko Maeda, Kuni Ohtomo
    • Journal Title

      Mass-Data Analysis of Images and Signals

      Volume: 2(1) Pages: 112-127

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] CIRCUS : An MDA platform for clinical image analysis in hospitals2010

    • Author(s)
      Yukihiro Nomura
    • Journal Title

      Trans.Mass-Data Analysis of Images and Signals

      Volume: 2(1) Pages: 112-127

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Motion-robust diffusion tensor acquisition at routine 3T magnetic resonance imaging2010

    • Author(s)
      Yasmin H, Masutani Y, et al.
    • Journal Title

      Japanese journal of radiology 28

      Pages: 27-33

    • NAID

      50007467428

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] Robust DKI Computation Method and its Application for Building Brain Atlas with Multiple Diffusion MRI Parameters2012

    • Author(s)
      Yoshitaka Masutani, Shigeki Aoki
    • Organizer
      CARS 2012
    • Place of Presentation
      Pisa, Italy
    • Year and Date
      2012-06-28
    • Related Report
      2011 Final Research Report
  • [Presentation] General Closed-from Expressions for DKI Parameters and Their Application to Fast and Robust DKI Computation based on Outlier Removal2012

    • Author(s)
      Yoshitaka Masutani, Shigeki Aoki
    • Organizer
      ISMRM 20th Scientific Meeting & Exhibition
    • Place of Presentation
      Melbourne, Australia
    • Year and Date
      2012-05-08
    • Related Report
      2011 Final Research Report
  • [Presentation] CIRCUS+:遠隔読影環境のための統合的診断支援およびCAD開発プラットフォーム2012

    • Author(s)
      増谷佳孝,野村行弘,三木聡一郎,臼井敦,大野孝,原真,松尾義朋,吉川健啓,林直人,大友邦
    • Organizer
      日本医学放射線学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2012-04-13
    • Related Report
      2011 Final Research Report
  • [Presentation] 拡散尖度イメージングにおける様々な計算手法の比較とそのアトラス構築への応用2012

    • Author(s)
      増谷佳孝,青木茂樹
    • Organizer
      電子情報通信学会医用画像研究会
    • Place of Presentation
      那覇
    • Year and Date
      2012-01-19
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] On closed form expression of diffusion kurtosis for more than 3 b values2011

    • Author(s)
      Yoshitaka Masutani, Shigeki Aoki
    • Organizer
      International Joint Symposium-Ultra High Field MRI
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      2011-11-07
    • Related Report
      2011 Final Research Report
  • [Presentation] On closed form expression of diffusion kurtosis for more than 3b values2011

    • Author(s)
      Masutani Y, Aoki S
    • Organizer
      International Joint Symposium-Ultra High Field MRI
    • Place of Presentation
      Tokyo
    • Year and Date
      2011-11-07
    • Related Report
      2011 Annual Research Report
  • [Presentation] 拡散MR画像の処理とその応用~基礎から最新動向まで~2011

    • Author(s)
      増谷
    • Organizer
      予防医工学研究会
    • Place of Presentation
      名古屋(招待講演)
    • Year and Date
      2011-10-31
    • Related Report
      2011 Annual Research Report
  • [Presentation] Tract-Specific Analysisのための全自動かつ高速な帯状束の抽出法に関する研究2011

    • Author(s)
      伊藤賢司,増谷佳孝,青木茂樹,鈴木雄一,井野賢司,國松聡,大友邦
    • Organizer
      第39回日本核磁気共鳴医学会大会
    • Place of Presentation
      北九州
    • Year and Date
      2011-10-01
    • Related Report
      2011 Final Research Report
  • [Presentation] Tract-Specific Analysisのための全自動かつ高速な帯状束の抽出法に関する研究2011

    • Author(s)
      伊藤、増谷、青木,鈴木、井野、國松、大友
    • Organizer
      日本核磁気共鳴医学会大会
    • Place of Presentation
      北九州
    • Year and Date
      2011-10-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] Diffusionalkurtosisimagingを利用した特発性正常圧水頭症の錐体路に関する検討2011

    • Author(s)
      福永一星,中西淳,堀正明,増谷佳孝,佐藤秀二,濱崎望,中島円,宮嶋雅一,新井一,青木茂樹,妹尾淳史
    • Organizer
      第39回日本核磁気共鳴医学会大会
    • Place of Presentation
      北九州
    • Year and Date
      2011-09-29
    • Related Report
      2011 Final Research Report
  • [Presentation] Diffusional kurtosis imagingを用いた多発性硬化症患者のnormal appearing white matterに対する定量解析2011

    • Author(s)
      吉田茉莉子,堀正明,福永一星,横山和正,濱崎望,鎌形康司,下地啓五,中西淳,鈴木由里子,桑鶴良平,笹井啓資,青木茂樹,増谷佳孝
    • Organizer
      第39回日本核磁気共鳴医学会大会
    • Place of Presentation
      北九州
    • Year and Date
      2011-09-29
    • Related Report
      2011 Final Research Report
  • [Presentation] Diffusional kurtosis imagingを利用した特発性正常圧水頭症の錐体路に関する検討2011

    • Author(s)
      福永、中西、堀、増谷、佐藤、濱崎、中島、宮嶋、新井、青木、妹尾
    • Organizer
      日本核磁気共鳴医学会大会
    • Place of Presentation
      日本核磁気共鳴医学会大会
    • Year and Date
      2011-09-29
    • Related Report
      2011 Annual Research Report
  • [Presentation] Diffusional kurtosis imagingを用いた多発性硬化症患者のnormal appearing white matterに対する定量解析2011

    • Author(s)
      吉田、堀、福永、横山、濱崎、鎌形、下地、中西、鈴木、桑鶴、笹井、青木、増谷
    • Organizer
      日本核磁気共鳴医学会大会
    • Place of Presentation
      北九州
    • Year and Date
      2011-09-29
    • Related Report
      2011 Annual Research Report
  • [Presentation] 拡散MRイメージングにおける解析的な拡散尖度計算の一手法2011

    • Author(s)
      増谷佳孝,青木茂樹
    • Organizer
      電子情報通信学会医用画像研究会
    • Place of Presentation
      札幌
    • Year and Date
      2011-07-12
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] A unified framework for concurrent detection of anatomical landmarks for medical image understanding2011

    • Author(s)
      Mitsutaka Nemoto, Yoshitaka Masutani, Shouhei Hanaoka, Yukihiro Nomura, Takeharu Yoshikawa, Naoto Hayashi, Naoki Yoshioka, Kuni Ohtomo
    • Organizer
      SPIE Medical Imaging 2011
    • Place of Presentation
      Orlando, USA
    • Year and Date
      2011-02-12
    • Related Report
      2011 Final Research Report
  • [Presentation] A unified framework for concurrent detection of anatomical landmarks for medical image understanding2011

    • Author(s)
      Mitsutaka Nemoto
    • Organizer
      SPIE Medical Imaging, 2011
    • Place of Presentation
      Orlando, Florida, USA
    • Related Report
      2010 Annual Research Report
  • [Presentation] 交叉線維部における局所HARDI撮影の追加によるTractographyの描出能向上2010

    • Author(s)
      伊藤賢司,増谷佳孝,鈴木雄一,青木茂樹,阿部修,國松聡,大友邦
    • Organizer
      第38回日本磁気共鳴医学会大会
    • Place of Presentation
      つくば
    • Year and Date
      2010-10-01
    • Related Report
      2011 Final Research Report
  • [Presentation] Q-Ball TractographyとfMRIを用いた皮質延髄路描出2010

    • Author(s)
      鈴木雄一,増谷佳孝,伊藤賢司,井野賢司,渡辺靖志,佐竹芳朗,後藤政実,飯田恭人,矢野敬一,大友邦
    • Organizer
      第38回日本磁気共鳴医学会大会
    • Place of Presentation
      つくば
    • Year and Date
      2010-10-01
    • Related Report
      2011 Final Research Report
  • [Presentation] 交叉線維部における局所HARDI 撮影の追加によるTractographyの描出能向上2010

    • Author(s)
      伊藤賢司
    • Organizer
      第38回日本磁気共鳴医学会大会
    • Place of Presentation
      つくば
    • Year and Date
      2010-10-01
    • Related Report
      2010 Annual Research Report
  • [Presentation] Q-Ball Tractography とfMRIを用いた皮質延髄路描出2010

    • Author(s)
      鈴木雄一
    • Organizer
      第38回日本磁気共鳴医学会大会
    • Place of Presentation
      つくば
    • Year and Date
      2010-10-01
    • Related Report
      2010 Annual Research Report
  • [Presentation] Designing Tract-adaptive MPG Sets for Faster Acquisition of HARDI Data2010

    • Author(s)
      Yoshitaka Masutani, Kenji Itoh, Yuichi Suzuki, Osamu Abe, Shigeki Aoki, Kuni Ohtomo
    • Organizer
      Computer Assisted Radiology and Surgery(CARS) 2010
    • Place of Presentation
      Geneva, Switzerland
    • Year and Date
      2010-06-22
    • Related Report
      2011 Final Research Report
  • [Presentation] HARDIにおけるMPG削減のための実験的一手法2010

    • Author(s)
      増谷佳孝,鈴木雄一,伊藤賢司,阿部修,青木茂樹,大友邦
    • Organizer
      電子情報通信学会医用画像研究会
    • Place of Presentation
      沖縄
    • Year and Date
      2010-01-28
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Presentation] Designing Tract-adaptive MPG Sets for Faster Acquisition of HARDI Data2010

    • Author(s)
      Yoshitaka Masutani
    • Organizer
      Computer Assisted Radiology and Surgery
    • Place of Presentation
      Geneva Switzerland
    • Related Report
      2010 Annual Research Report
  • [Presentation] 錐体路を対象とした確率的Tractographyの臨床撮像条件における描出比較2009

    • Author(s)
      伊藤賢司,鈴木雄一,増谷佳孝,青木茂樹,阿部修,大友邦
    • Organizer
      第37回日本磁気共鳴医学会大会
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-02
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Presentation] 脳梁通過線維の確率的Tractographyにおける臨床データでの描出比較2009

    • Author(s)
      鈴木雄一,伊藤賢司,増谷佳孝,井野賢司,佐竹芳朗,飯田恭人,矢野敬一,青木茂樹,阿部修,美馬和男,大友邦
    • Organizer
      第37回日本磁気共鳴医学会大会
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-02
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Presentation] 拡散MRIに基づく確率的Tractographyにおける描出パラメータの局所調整による改善の一手法2009

    • Author(s)
      伊藤賢司,増谷佳孝,青木茂樹,阿部修,大友邦
    • Organizer
      第28回日本医用画像工学会
    • Place of Presentation
      名古屋
    • Year and Date
      2009-08-04
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Presentation] diffusion Tensor Visualizer II Second Release by UTRAD/ICAL2009

    • Author(s)
      Yoshiyaka Masutani
    • Organizer
      Weekend Educational Course of the International Society for Magnetic Resonance in Medicine(ISMRM) 17th Scientific Meeting & Exhibition
    • Place of Presentation
      Honolulu, USA
    • Year and Date
      2009-04-18
    • Related Report
      2011 Final Research Report
  • [Presentation] diffusion Tensor Visualizer II Second Release by UTRAD/ICAL2009

    • Author(s)
      Masutani Y
    • Organizer
      the Weekend Educational Course of the ISMRM 17th Scientific Meeting & Exhibition
    • Place of Presentation
      Honolulu(USA)
    • Year and Date
      2009-04-18
    • Related Report
      2009 Annual Research Report
  • [Book] Medical Imaging Intelligence and Analysis2012

    • Author(s)
      Yoshitaka Masutani, Mitsutaka Nemoto, Yukihiro Nomura, Naoto Hayashi
    • Publisher
      Machine Learning in Computer-Aided Diagnosis
    • Related Report
      2011 Final Research Report
  • [Book] (Chap.8) Clinical Machine Learning in Action : CAD System Design, Development, Tuning, and Long-Term Experience, in Machine Learning in Computer-Aided Diagnosis : Medical Imaging Intelligence and Analysis(K.Suzuki (ed.))2012

    • Author(s)
      Y.Masutani, et al.
    • Publisher
      IGI Global
    • Related Report
      2011 Annual Research Report
  • [Remarks] 招待講演(1)増谷佳孝,拡散MR画像の処理とその応用~基礎から最新動向まで~,予防医工学研究会, 2011. 10. 31,名古屋

    • Related Report
      2011 Final Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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