A study on microplanar beam radiation therapy at high energy X rays(≧1MeV)
Project/Area Number |
21340066
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Research Category |
Grant-in-Aid for Scientific Research (B)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Particle/Nuclear/Cosmic ray/Astro physics
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Research Institution | Waseda University |
Principal Investigator |
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Co-Investigator(Kenkyū-buntansha) |
WASHIO Masakazu 早稲田大学, 理工学術院, 教授 (70158608)
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Co-Investigator(Renkei-kenkyūsha) |
KONDOH Takeshi 神戸大学, 医学部, 医学研究員 (50273769)
NARIYAMA Nobuteru (財)高輝度光科学研究センター, 光源光学系部門, 研究員 (20344393)
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Project Period (FY) |
2009 – 2011
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Project Status |
Completed (Fiscal Year 2011)
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Budget Amount *help |
¥19,500,000 (Direct Cost: ¥15,000,000、Indirect Cost: ¥4,500,000)
Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2010: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
Fiscal Year 2009: ¥11,180,000 (Direct Cost: ¥8,600,000、Indirect Cost: ¥2,580,000)
|
Keywords | 放射線治療法 / 加速器 / 微小平板ビーム / モンテカルロコード / ガフクロミックフィルム / 顕微分光 / マイクロドシメトリー / グリオーマ / 徴小平板ビーム / 高エネルギーX線 / マイクロアレイ解析 |
Research Abstract |
A study on microplanar beam radiation therapy(MRT) has demonstrated the following points : for the animal study at SPring-8, alignment of a collimator is very important to obtain a symmetrical beam profile for irradiation ; hypoxic fraction of tumor cells after MRT treatment was increased, which may explain the selective killing of tumor cells by MRT ; as for a beam width, narrow beam was more effective than wider beam, which suggests that an appropriate beam width must be exist ; and for the X-ray energy, high energy such as 1 MeV was not applicable and the most effective energy will be in the range of 100-250 keV.
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Report
(4 results)
Research Products
(37 results)
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[Presentation] 早稲田大学フォトカソードRF電子銃における応用研究の現状と今後の展望2010
Author(s)
坂上和之, 青木達朗, 篠原邦夫, 鈴木達也, 別當良介, 保坂勇志, 横山悠久, 鷲尾方一, 浦川順治, 照沼信浩, 早野仁司, 柏木茂, 黒田隆之助
Organizer
第7回日本加速器学会年会
Place of Presentation
姫路市文化センター(姫路市)
Year and Date
2010-08-04
Related Report
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