Technology of^3He Imaging with polarized^3He gas

• Project/Area Number: 21340067
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Particle/Nuclear/Cosmic ray/Astro physics
• Research Institution: Kobe Tokiwa University
• Principal Investigator: TANAKA Masayoshi 神戸常盤大学, 保健科学部, 教授 (70071397)
• Co-Investigator(Kenkyū-buntansha): FUJIWARA Mamoru 大阪大学, 核物理研究センター, 准教授 (00030031) ; KOHRI Hideki 大阪大学, 核物理研究センター, 助教 (40448022) ; TAKAMATSU Kunihiko 神戸常盤大学・短期大学部, 口腔保健学科, 助教 (80392017)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥18,980,000 (Direct Cost: ¥14,600,000、Indirect Cost: ¥4,380,000); Fiscal Year 2011: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000); Fiscal Year 2010: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000); Fiscal Year 2009: ¥10,790,000 (Direct Cost: ¥8,300,000、Indirect Cost: ¥2,490,000)
• Keywords: 超偏極MRI / 強制偏極法 / 高速融解法 / 核スピンイメージング / ポメランチュクセル / ^3He/^4He希釈冷凍機 / 超偏極^3He-MRI / ポメランチュク冷却 / 液体^3HeのNMRスペクトル / MRI / 急速融解 / Brute force method / COPD(慢性閉塞性肺疾患) / ^3He / ^4He希釈冷凍機 / 熱スイッチ

Research Abstract

We have developed a method to create the hyperpolarized, i. e., highly polarized^3He gas for the^3He-MRI using the Brute Force Method(BFM), where an extremely low temperature(～ 10mK), and a strong magnetic field(～ 17T) are employed. The reason why we use the BFM is that the production rate of the hyperpolarized^3He created by the well established laser optical pumping is limited to about 1 liter/day, while that for the BFM is expected to exceed 1000 liter/day.
Currently, we use the^3He/^4He cryogenic system(DRS2500) introduced from the Leiden Cryogenics, the Netherlands to realize a temperature lower than 10mK together with a Pomeranchuk cell, and the superconducting solenoidal coil to realize a strong magnetic field of 17T. We are almost ready to check the validity of the vaporization of the hyperpolarized solid^3He through a liquid phase without sizable spin relaxation by use of a method called a rapid melting method. We have started a preliminary experiment toward the production of the hyperpolarized^3He gas.

Research Products

• [Journal Article] Feasibility study on the nuclear spion imaging(NSI) (2012)
  • Author(s): M. Tanaka, T. Kunimatsu, M. Fujiwara, H. Kohri, T. Ohta, M. Utsuro, M. Yosoi, T. Akenaga, S. Imoto, K. Takamatsu, K. Ueda, J. P. Didelez, G. Frossati, and A. de Waard
  • Journal Title: Proceedings of Science(POS) Volume: (in press)
  • Peer Reviewed
• [Journal Article] Distillation of hydrogen isotopes for polarized HD targets (2012)
  • Author(s): T. Ohta, S. Bouchigny, J. P. Didelez, M. Fujiwara, K. Fukuda, H. Kohri, T. Kunimatsu, C. Morisaki, S. Ono, eda, G. Rouille, M. Tanaka, K. Ueda, M. Uraki, M. Utsuro, S. Y. Wang, M. Yosoi
  • Journal Title: Nucl. Instr. Meth Volume: A664 Pages: 347-352
  • Peer Reviewed
• [Journal Article] Production of polarized^3He gas by means of very low temperature and high magnetic field (2012)
  • Author(s): M. Tanaka, T. Inomata, Y. Takahashi, M. Fujiwara, M. Yosoi, H. Kohri, T. Ohta, C. Morisaki, and T. Kunimatsu
  • Journal Title: Bulletin of Kobe Tokiwa University Pages: 42-47
  • NAID: 120006318489
  • URL: http://bulletin.kobe-tokiwa.ac.jp/_userdata/ktu_kiyou01_05.pdf
  • Peer Reviewed
• [Journal Article] Distillation of hydrogn isotopes for polarized HD target (2012)
  • Author(s): 太田岳史, 他
  • Journal Title: Nuclear Instruments and Methods in Physics Research A Elsvier, The Netherlands Volume: 664 Pages: 347-352
  • Peer Reviewed
• [Journal Article] HD gas analysis with gas chromatography and quadrupole mass spectrometer (2011)
  • Author(s): T. Ohta, S. Bouchigny, J. P. Didelez, M. Fujiwara, K. Fukuda, H. Kohri, T. Kunimatsu, C. Morisaki, S. Ono, G. Rouille, M. Tanaka, K. Ueda, M. Uraki, M. Utsuro, S. Y. Wang, M. Yosoi
  • Journal Title: Nucl. Instr. Meth Volume: A640 Pages: 241-246
  • Peer Reviewed
• [Journal Article] Development of portable NMR system for polarized HD target (2011)
  • Author(s): T. Ohta, M. Fujiwara, K. Fukuda, H. Kohri, T. Kunimatsu, C. Morisaki, S. Ono, M. Tanaka, K. Ueda, M. Uraki, M. Utsuro, S. Y. Wang, and M. Yosoi
  • Journal Title: Nucl. Instr. Meth Volume: A633 Pages: 46-50
  • Peer Reviewed
• [Journal Article] Nuclear spin imaging with hyperpolarized nuclei created by brute force method (2011)
  • Author(s): M. Tanaka, T. Kunimatsu, M. Fujiwara, H. Utsuro, M. Yosoi, S. Ono, K. Fukuda, K. Takamatsu, K. Ueda, J. P. Didelez, G. Frossati, and A. de Waard
  • Journal Title: Physics Conference Series Volume: 295 Pages: 1-5
  • Peer Reviewed
• [Journal Article] Brute-force polarized solid H^3e and possible application to the production of polarized gas for medical. use (2011)
  • Author(s): M. Tanaka, T. Akenaga, K. Takamatsu, K. Ueda, T. Kunimatsu, M. Fujiwara, H. Kohri, T. Ohta, M. Utsuro, K. Fukuda, J. P. Didelez, G. Frossati, and A. de Waard
  • Journal Title: Proceedings of PSTP2011 Pages: 146-149
• [Journal Article] Nuclear Spin Imaging by Using Hyperpolarized Nuclei Created by Brute-force Method (2011)
  • Author(s): 田中正義, 他
  • Journal Title: Journal of Physics : Conference Series(出版社:IOP Publishing) Volume: 295
  • Peer Reviewed
• [Journal Article] Development of portable NMR polarimeter system for polarized HD target (2011)
  • Author(s): 太田岳史, 他
  • Journal Title: Nuclear Instruments and Methods, Physics Research A Volume: 533 Pages: 46-50
  • Peer Reviewed
• [Journal Article] HD gas analysis by using gas chromatography and quadrupole massspectrometer (2011)
  • Author(s): 太田岳史, 他
  • Journal Title: Nuclear Instruments and Methods, Physics Research A Volume: (印刷中)
  • Peer Reviewed
• [Journal Article] Polarized HD target for future Leps Experiments at Spring-8 in Japan (2010)
  • Author(s): H. Kohri, M. Fujiwara, M. Fukuda, T. Hotta, T. Kunimatsu, C. Morisaki, T. Ohta, S. Ono, K. Ueda, M. Uraki, M. Utsuro, M. Yosoi, S. Y. Wang, S. Bouchigny, J. P. Didelez, G. Rouille, and M. Tanaka
  • Journal Title: Int. J. Modern Phys. E(IJMPEA) Pages: 903-914
• [Journal Article] Production of polarized ^3He gas by means of very low temperature and high magnetic field (2009)
  • Author(s): 田中正義、猪股亨, 他
  • Journal Title: 神戸常盤大学紀要 創刊号 Pages: 41-47
  • NAID: 120006318489
  • Peer Reviewed
• [Journal Article] Production of polarized ^3He gas by means of cryogenic method (2009)
  • Author(s): 猪股亨、田中正義, 他
  • Journal Title: RCNP Annual Report 2009 Pages: 52-52
• [Journal Article] Nuclear spin imaging with hyperpolarized nuclei created by brute forcemethod
  • Author(s): 田中正義, 他
  • Journal Title: POS (Proceedings of Science) organized by th SISSA, Italy Volume: (to be published)
  • Peer Reviewed
• [Presentation] Nuclear spin imaging with hyperpolarized nuclei created by brute force method (2011)
  • Author(s): 田中正義
  • Organizer: WPCF2011 VII Workshop on particle correlations and femtoscopy
  • Place of Presentation: 東京大学小柴記念館、日本
  • Year and Date: 2011-09-22
• [Presentation] Polarized solid ^3He target created by the brute force method for medical use (2011)
  • Author(s): 田中正義
  • Organizer: PSTP2011 XIV International Workshop on Polarized Sources, Targets and Polarimetry
  • Place of Presentation: サンクトペテルブルグ、ロシア
  • Year and Date: 2011-09-15
• [Presentation] Development of polarized HD target for LEPS experiments (2011)
  • Author(s): 郡英輝
  • Organizer: PSTP2011 XIV International Workshop on Polarized Sources, Targets and Polarimetry
  • Place of Presentation: サンクトペテルブルグ、ロシア
  • Year and Date: 2011-09-15
• [Presentation] Polarized solid^3He target created by the brute force method for medical use (2011)
  • Author(s): 田中正義
  • Organizer: 14^<th> International Workshop on Polarized Sources, Targets & Polarimetry
  • Place of Presentation: ロシア、サンクトペテルブルグ
• [Presentation] Development of polarized HD target for LEPS experiment (2011)
  • Author(s): 郡英輝
  • Organizer: 14^<th> International Workshop on Polarized Sources, Targets & Polarimetry
  • Place of Presentation: ロシア、サンクトペテルブルグ
• [Presentation] Nuclear spin imaging with hyperpolarized nuclei created by brute forece method (2011)
  • Author(s): 田中正義
  • Organizer: The 7^<th> Workshop on Particle Correlations and Femtoscopy(WPCF2011)
  • Place of Presentation: 東京大学小柴記念館
• [Presentation] 核スピンイメージング(NSI)法開発の現状 (2011)
  • Author(s): 田中正義
  • Organizer: 第2回総合スピン科学シンポジュウム
  • Place of Presentation: 山形大学理学部
• [Presentation] Nuclear Spin Imaging by Using Hyperpolarized Nuclei Created by Brute-force Method (2010)
  • Author(s): 田中正義
  • Organizer: SPIN2010(スピン物理国際シンポジューム)
  • Place of Presentation: ドイツ・ユーリッヒ(Institute for Nuclear Physics)
  • Year and Date: 2010-09-27
• [Presentation] MRIを用いた核スピンイメージング法のための高偏極^3Heガス生成II (2010)
  • Author(s): 国松貴之
  • Organizer: 日本物理学会
  • Place of Presentation: 九州工大
  • Year and Date: 2010-09-11
• [Presentation] MRIを用いた核スピンイメージング法のための高偏極^3Heガス生成 (2010)
  • Author(s): 國松貴之
  • Organizer: 日本物理学会
  • Place of Presentation: 岡山大学
• [Presentation] MRIを用いた核スピンイメージング法のための高偏極^3Heガス生成II (2010)
  • Author(s): 國松貴之
  • Organizer: 日本物理学会
  • Place of Presentation: 九州工業大学
• [Presentation] Polarized solid^3He target created by the brute force method for medical use (2010)
  • Author(s): 田中正義
  • Organizer: The 19^<th> International Spin Physics Symposium(SPIN20100)
  • Place of Presentation: Institute for Nuclear Physics(IKP),ドイツ
• [Remarks]
• [Remarks]
  • URL: http://www.rcnp.osaka-u.ac.jp/~kohri
• [Remarks]
  • URL: http://www.rcnp.osaka-u.ac.jp/kohri
• [Remarks]
  • URL: http://www.rcnp.osaka-u.ac.jp/~kohri
• [Remarks] (工事中)
  • URL: http://www.rcnp.osaka-u.ac.jp/~tanaka