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Exploratory study of a usability of gene information on the health promotion and prevention of disease in the community setting

Research Project

Project/Area Number 21390168
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Medical sociology
Research InstitutionJichi Medical University

Principal Investigator

OKAYAMA Masanobu  自治医科大学, 医学部・医学科, 准教授 (10285801)

Co-Investigator(Kenkyū-buntansha) KJII Eiji  自治医科大学, 医学部・医学科, 教授 (40204391)
KAMESAKI Toyomi  自治医科大学, 医学部・医学科, 准教授 (90316513)
KUMADA Maki  自治医科大学, 医学部・医学科, 准教授 (40326830)
KOMATSU Kenichi  自治医科大学, 医学部・医学科, 助教 (70364510)
KANDA Takefumi  自治医科大学, 医学部・医学科, 助教 (10528673)
TAKESHIMA Tarou  自治医科大学, 医学部・医学科, 助教 (50554565)
KENZAKA Tsuneaki  自治医科大学, 医学部・医学科, 助教 (90437492)
今野 和典  自治医科大学, 医学部, 助教 (40528676)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥19,500,000 (Direct Cost: ¥15,000,000、Indirect Cost: ¥4,500,000)
Fiscal Year 2011: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2010: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
Fiscal Year 2009: ¥8,320,000 (Direct Cost: ¥6,400,000、Indirect Cost: ¥1,920,000)
Keywords遺伝子情報 / 生活習慣病 / 行動変容 / 健康教育 / 遺伝子頻度 / 地域差 / 高血圧 / 遺伝子 / SNP / 塩分摂取 / 遺伝子検査 / GNB3 / 生活習慣
Research Abstract

This study found that people worrying about some disease were likely to take genetic tests detecting the susceptibility to the same disease. Thus they may be more easily affected by the tests than others. The questionnaire survey found that the negative genetic test had risk to recurrence an undesirable lifestyle, especial in people restricting their preferred lifestyle. The genetic information should be carefully informed in this case. It is found that the effect of the notification of the genetic test was not observed in most items about the lifestyle. Although we need detailed analyses in future, the genetic tests might not be usable to the health promotion and prevention of disease.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (14 results)

All 2011 2010 2009 Other

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Presentation (9 results) Remarks (1 results)

  • [Journal Article] Regulatory SNP in the RBP4 gene modified the expression in adipocytes and associated with BMI2010

    • Author(s)
      Munkhtulga L, Kumada M(8番目), et al(18名)
    • Journal Title

      Obesity

      Volume: 18 Pages: 1006-14

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] A nationwide survey of hepatitis E virus infection in the general population of Japan2010

    • Author(s)
      Takahashi M, Okayama M((8番目), Kajii E(10番目), et al(11名)
    • Journal Title

      J Med Virol

      Volume: 82 Pages: 271-81

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Regulatory SNP in the RBP4 gene modified the expression in adipocytes and associated with BMI2010

    • Author(s)
      熊田真樹, 他
    • Journal Title

      Obesity 18

      Pages: 1006-14

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A nationwide survey of hepatitis E virus infection in the general population of Japan2010

    • Author(s)
      岡山雅信, 他
    • Journal Title

      J Med Virol 82

      Pages: 271-281

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] 大規模地域ゲノムバンク/生活習慣介入研究:生活習慣への遺伝子の位置づけ2011

    • Author(s)
      岡山雅信
    • Organizer
      STSNJ :夏の学校2011
    • Place of Presentation
      高松市
    • Year and Date
      2011-08-27
    • Related Report
      2011 Final Research Report
  • [Presentation] 大規模地域ゲノムバンク/生活習慣介入研究:生活習慣介入への遺伝子情報の位置づけ2011

    • Author(s)
      岡山雅信
    • Organizer
      STSNJ:夏の学校2011
    • Place of Presentation
      香川県高松市(招待講演)
    • Year and Date
      2011-08-27
    • Related Report
      2011 Annual Research Report
  • [Presentation] SNP-SNP Interactions among hypertension related genes2011

    • Author(s)
      Etou M, Okayama M, Kajii E, et al
    • Organizer
      26^<th> Annual Scientific Meeting and Exposition, American Society of Hypertension
    • Place of Presentation
      New York
    • Year and Date
      2011-05-22
    • Related Report
      2011 Final Research Report
  • [Presentation] SNP-SNP Interactions among hypertension related genes2011

    • Author(s)
      Etou M、Okayama M, et al
    • Organizer
      26th Annual Scientific Meeting and Exposition, American Society of Hypertension
    • Place of Presentation
      New York, USA
    • Year and Date
      2011-05-22
    • Related Report
      2011 Annual Research Report
  • [Presentation] Community-based analysis of genetic factors associated with gender-specific hypertension in Japan2010

    • Author(s)
      Etou M, Okayama M, Kajii E, et al
    • Organizer
      25^<th> Annual Scientific Meeting and Exposition, American Society of Hypertension
    • Place of Presentation
      New York
    • Year and Date
      2010-05-02
    • Related Report
      2011 Final Research Report
  • [Presentation] 涌谷町における生活習慣病関連候補遺伝子の解析2009

    • Author(s)
      江藤雅彦、岡山雅信、梶井英治, 他
    • Organizer
      第49回全国国保地域医療学会
    • Place of Presentation
      仙台市
    • Year and Date
      2009-10-03
    • Related Report
      2011 Final Research Report
  • [Presentation] 山口県の離島と山間部における生活習慣病関連遺伝子のアレル出現頻度の相違2009

    • Author(s)
      原田昌範、岡山雅信、梶井英治, 他
    • Organizer
      第32回プライマリ・ケア学会
    • Place of Presentation
      京都市
    • Year and Date
      2009-08-22
    • Related Report
      2011 Final Research Report
  • [Presentation] 涌谷町における高血圧のリスク因子の検討: 1塩基多型(SNP)について2009

    • Author(s)
      江藤雅彦、岡山雅信、梶井英治, 他
    • Organizer
      第107回日本内科学会総会・講演会
    • Place of Presentation
      東京
    • Year and Date
      2009-08-22
    • Related Report
      2011 Final Research Report
  • [Presentation] 山口県の離島と山間部における生活習慣病関連遺伝子のアレル出現頻度の相違2009

    • Author(s)
      岡山雅信, 他
    • Organizer
      第32回プライマリ・ケア学会
    • Place of Presentation
      国立京都国際会館(京都部)
    • Year and Date
      2009-08-22
    • Related Report
      2009 Annual Research Report
  • [Remarks]

    • URL

      http://www.jichi.ac.jp/usr/tiik/

    • Related Report
      2011 Final Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

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