血液凝固線溶系を指標とした幼児期からのメタボリックシンドロームの予防に関する研究
| Project/Area Number |
21500680
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied health science
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| Research Institution | University of Tsukuba |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KAMODA Tomohiro 筑波大学, 医学医療系, 准教授 (50224704)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | メタボリックシンドローム / 小児肥満症 / 血液凝固線溶系 / アディポカイン / 血管内皮機能 / 小児 / 肥満 / アデイポカイン |
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| Research Abstract |
The metabolic syndrome is considered to originate in fetal life through childhood. In this study, we established the metabolic syndrome related hematological reference values, including adipokines and hemostatic/fibrinolytic systems, in Japanese children. These parameters are associate with BMI and central obesity, and strongly correlate to uric acid(UA), leptin and fibrinogen. This study suggests that changes in adipokines and hemostatic/fibrinolytic systems during early childhood contribute to the development of metabolic syndrome.
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Report
(4 results)
Research Products
(14 results)
