• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Realizing desired quality through gray-box models integrating first principles and statistical analysis

Research Project

Project/Area Number 21560793
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Reaction engineering/Process system
Research InstitutionKyoto University

Principal Investigator

KANO Manabu  京都大学, 大学院・工学研究科, 准教授 (30263114)

Co-Investigator(Kenkyū-buntansha) HASEBE Shinji  京都大学, 大学院・工学研究科, 教授 (60144333)
TONOMURA Osamu  京都大学, 大学院・工学研究科, 助教 (70402956)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywordsプロセス情報処理 / モデリング / 仮想計測技術 / ソフトセンサー / グレイボックスモデル / Locally Weighted Partial Least Squares(LW-PLS) / 産業応用 / 品質実現力 / Locally Weighted Partial Least Squares / Process Analytical Technology / Virtual Metrology / グリイボックスモデル / Just-In-Timeモデル / データ解析 / 要因解析 / スペクトラルクラスタリング / Partial Least Squares / 独立成分分析
Research Abstract

A gray-box model integrating a physical model and a statistical model was developed, and also locally weighted PLS that can cope with changes in process characteristics was developed. The gray-box model was applied to a control problem of molten steel temperature in a tundish in the steel industry. The locally weighted PLS was applied to various processes in pharmaceutical, semiconductor, and petrochemical industries. The achievement of this research was significant and awarded a prize from The Iron and Steel Institute of Japan ; further development and industrial applications are expected.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (21 results)

All 2012 2011 2010

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Presentation (17 results)

  • [Journal Article] Evaluation of Infrared-Reflection Absorption Spectroscopy Measurement and Locally Weighted Partial Least-Squares for Rapid Analysis of Residual Drug Substances in Cleaning Processes2012

    • Author(s)
      Hiroshi Nakagawa, Takahiro Tajima, Manabu Kano, Sanghong Kim, Shinji Hasebe, Tatsuya Suzuki, Hiroaki Nakagami
    • Journal Title

      Analytical Chemistry

      Volume: 84 Pages: 3820-3826

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of Infrared-Reflection Absorption Spectroscopy Measurement and Locally Weighted Partial Least-Squares for Rapid Analysis of2012

    • Author(s)
      Hiroshi Nakagawa
    • Journal Title

      Analytical Chemistry

      Volume: 84 Issue: 8 Pages: 3820-3826

    • DOI

      10.1021/ac202443a

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Estimation of Active Pharmaceutical Ingredients Content Using Locally Weighted Partial Least Squares and Statistical Wavelength Selection2011

    • Author(s)
      Sanghong Kim, Manabu Kano, Hiroshi Nakagawa, Shinji Hasebe
    • Journal Title

      International Journal of Pharmaceutics

      Volume: 421 Pages: 269-274

    • NAID

      120003644400

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Estimation of Active Pharmaceutical Ingredients Content Using Locally Weighted Partial Least Sauares and Statistical Wavelength Selection2011

    • Author(s)
      Sanghong Kim
    • Journal Title

      International Journal of Pharmaceutics

      Volume: 421 Issue: 2 Pages: 269-274

    • DOI

      10.1016/j.ijpharm.2011.10.007

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Presentation] Estimation of Active Pharmaceutical Ingredient Content Using Locally Weighted Partial Least Squares2012

    • Author(s)
      Sanghong Kim, Manabu Kano, Hiroshi Nakagawa, Shinji Hasebe
    • Organizer
      Chemical Process Control
    • Place of Presentation
      US
    • Related Report
      2011 Final Research Report
  • [Presentation] Estimation of Active Pnarmaceutical Ingredient Content Using Locally Weighted Partial Least Squares2012

    • Author(s)
      Sanghong Kim
    • Organizer
      Chemical Process Control
    • Place of Presentation
      Savannah, US
    • Related Report
      2011 Annual Research Report
  • [Presentation] プロセス産業における仮想計測技術の現状と課題解決に向けた産学共同研究2011

    • Author(s)
      加納学
    • Organizer
      計測自動制御学会産業応用部門大会
    • Place of Presentation
      東京(招待講演)
    • Year and Date
      2011-11-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] Does Virtual Sensing Technology Work at Your Workplace?-Proper Use of Process Data Analysis2011

    • Author(s)
      Manabu Kano
    • Organizer
      AEC/APC Symposium Asia
    • Place of Presentation
      Tokyo, Japan(招待講演)
    • Year and Date
      2011-11-09
    • Related Report
      2011 Annual Research Report
  • [Presentation] QbD/PATに基づいてRTRTを実現するための多変量解析技術2011

    • Author(s)
      加納学
    • Organizer
      製剤機械技術学第21回大会(招待講演)
    • Place of Presentation
      静岡
    • Year and Date
      2011-08-14
    • Related Report
      2011 Final Research Report
  • [Presentation] QbD/PATに基づいてRTRTを実現するための多変量解析技術2011

    • Author(s)
      加納学
    • Organizer
      製剤機械技術学第21回大会
    • Place of Presentation
      静岡(招待講演)
    • Year and Date
      2011-08-14
    • Related Report
      2011 Annual Research Report
  • [Presentation] High Performance Prediction of Molten Steel Temperature through Gray-Box Model2011

    • Author(s)
      Toshinori Okura, Manabu Kano, Shinji Hasebe, Hiroshi Kitada, Noboru Murata
    • Organizer
      AIChE Annual Meeting
    • Place of Presentation
      US
    • Related Report
      2011 Final Research Report
  • [Presentation] Selection of Similarity Measure for Locally Weighted Partial Least Squares Regression2011

    • Author(s)
      Ryota Okajima, Sanghong Kim, Manabu Kano, Shinji Hasebe
    • Organizer
      AIChE Annual Meeting
    • Place of Presentation
      US
    • Related Report
      2011 Final Research Report
  • [Presentation] High Performance Prediction of Molten Steel Temperature through Gray-Box Model2011

    • Author(s)
      Toshinori Okura
    • Organizer
      AIChE Annual Meeting
    • Place of Presentation
      Minneapolis, US
    • Related Report
      2011 Annual Research Report
  • [Presentation] Selection of Similarity Measure for Locally Weighted Partial Least Squares Regression2011

    • Author(s)
      Ryota Okajima
    • Organizer
      AIChE Annual Meeting
    • Place of Presentation
      Minneapolis, US
    • Related Report
      2011 Annual Research Report
  • [Presentation] 取鍋およびタンディッシュ内溶鋼温度推定モデルの構築2011

    • Author(s)
      大倉才昇
    • Organizer
      日本鉄鋼協会第161回春季講演大会
    • Place of Presentation
      東京都市大学(東京)
    • Related Report
      2010 Annual Research Report
  • [Presentation] NIRと局所PLSによる顆粒中主薬濃度の推定2011

    • Author(s)
      金尚弘
    • Organizer
      化学工学会第76年会
    • Place of Presentation
      東京農工大学(東京)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 非線形システムを対象とした適応的なPLSモデル構築手法2011

    • Author(s)
      金尚弘
    • Organizer
      計測自動制御学会第11回制御部門大会
    • Place of Presentation
      琉球大学(沖縄)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 局所回帰モデルによる半導体プロセスドライエッチ工程の品質管理2011

    • Author(s)
      平井都志也
    • Organizer
      計測自動制御学会第11回制御部門大会
    • Place of Presentation
      琉球大学(沖縄)
    • Related Report
      2010 Annual Research Report
  • [Presentation] NC-スペクトラルクラスタリングとそのソフトウェアセンシングへの応用2010

    • Author(s)
      藤原幸一, 加納学, 長谷部伸治
    • Organizer
      計測自動制御学会 制御部門大会
    • Place of Presentation
      熊本
    • Year and Date
      2010-03-16
    • Related Report
      2009 Annual Research Report
  • [Presentation] Estimation of Active Pharmaceutical Ingredients Content in Blending Process for Drug Products Manufacturing2010

    • Author(s)
      Sanghong Kim
    • Organizer
      AIChE Annual Meeting
    • Place of Presentation
      Salt Lake City, US
    • Related Report
      2010 Annual Research Report
  • [Presentation] 医薬品製造プロセスにおける含量均一性推定手法の開発2010

    • Author(s)
      金尚弘
    • Organizer
      化学工学会第42回秋季大会
    • Place of Presentation
      同志社大学(京都)
    • Related Report
      2010 Annual Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi