Studies on gastrointestinal mucosa-maintaining factors produced during digestion of foods
| Project/Area Number |
21580141
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Food science
|
|---|
| Research Institution | The University of Tokushima |
|---|
Principal Investigator |
TANAKA Tamotsu 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 准教授 (90258301)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
TOKUMURA Akira 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 教授 (00035560)
|
|---|
| Project Period (FY) |
2009 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2009: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
|
|---|
| Keywords | 食品 / 消化管粘膜保護 / ホスファチジン酸 / 抗潰瘍 / リン脂質 / セラミド1-リン酸 / 消化管 / 粘膜上皮細胞 / 創傷治癒 / リゾボスファチジン酸 / 抗消化性潰瘍 / 粘膜上皮組織 / 細胞遊走 |
|---|
| Research Abstract |
Studies on gastrointestinal mucosa-maintaining factors in foods and digested foods were conducted. We found that phosphatidic acid(PA), a characteristic phospholipid in plant foodstuffs, effectively ameliorates aspirin-induced stomach ulcer. The lysophosphatidic acid produced by the hydrolysis of the PA was involved in the ulcer-ameliorating activity of PA. We also identified phytoceramide-1-phsphate as a novel sphingophospholipid with anti-apoptotic activity in cabbage leaves.
|
Report
(4 results)
Research Products
(31 results)
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
[Presentation] 種々の食材中の創傷治癒性リン脂質含量2011
Author(s)
葛西彩香, 木下正文, 足立美佳, 盛重純一, 瓜倉真衣, 里内清, 柏田良樹, 今林潔, 高石喜久, 田中保, 徳村彰
Organizer
日本農芸化学会中四国支部第29回講演会
Place of Presentation
徳島・徳島大学薬学部
Year and Date
2011-01-22
Related Report
-
-
-
-
-
-
-
-
[Presentation] Formation of lysophosphatidic acid, a wound-healing lipid, during digestion of cabbage leaves2010
Author(s)
Tamotsu Tanaka, Jun-ichi Morishige, Hiroki Kondo, Masafumi Kinoshita, Mika Adachi, Mai Urikura, Kiyoshi Satouchi, Akira Tokumura
Organizer
Keystone Symposia, Bioactive lipis : Biochemistry and Diseases
Place of Presentation
京都(ウエスティン都ホテル京都)
Year and Date
2010-06-09
Related Report
-
-
-
-
-
-
-
