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Establishment of biomarker panel for the early detection of atherosclerosis and the prevention of the cardio-renal syndromes in obesity and metabolic syndrome-role of the phenotypes and the function of peripheral blood monocytes-

Research Project

Project/Area Number 21590646
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Laboratory medicine
Research InstitutionDepartment of Clinical Research, National Hospital Organization Kyoto Medical Center

Principal Investigator

SATOH Noriko  独立行政法人国立病院機構(京都医療センター臨床研究センター), 糖尿病研究部, 研究室長(臨床代謝栄養) (80373512)

Co-Investigator(Kenkyū-buntansha) HASEGAWA Koji  独立行政法人国立病院機構(京都医療センター臨床研究センター), 展開医療研究部, 部長 (50283594)
KOTANI Kazuhiko  独立行政法人国立病院機構(京都医療センター臨床研究センター), 臨床研究企画運営部, 客員室長 (60335510)
Co-Investigator(Renkei-kenkyūsha) OGAWA Yoshihiro  東京医科歯科大学, 大学院・医歯学総合研究科・分子内分泌内科学分野, 教授 (70291424)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords内科 / 脂質 / 医療・福祉 / 遺伝子 / 動脈硬化
Research Abstract

We have revealed that the phenotypes of monocyte(inflammatory M1 type and anti-inflammatory M2 type : qualitative changes) are significantly associated with the known cardiovascular risks and that unfavorable pro-inflammatory(M1)/anti-inflammatory(M2)-like phenotypes of peripheral blood monocytes are improved by the treatment with diabetic or anti-hyperlipidemic drugs in Japanese patients with obesity and metabolic syndrome from 1050 subjects in the database of National Hospital Organization. Accordingly, these data suggest the efficacy of the measurement of phenotypes of monocytes for early detection of atherosclerosis and the prevention of cardiovascular diseases in obesity and metabolic syndrome.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (141 results)

All 2012 2011 2010 2009 Other

All Journal Article (50 results) (of which Peer Reviewed: 33 results) Presentation (83 results) Book (7 results) Remarks (1 results)

  • [Journal Article]2012

    • Author(s)
      Satoh-Asahara N, Shimatsu A, Sasaki Y, Nakaoka H, Himeno A, Tochiya M, Kono S, Takaya T, Ono K, Wada H, Suganami T, Koji Hasegawa K, and Ogawa Y
    • Journal Title

      Diabetes Care

      Volume: (in press)

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Salivary cortisol levels are associated with outcomes of weight reduction therapy in obese Japanese patients2012

    • Author(s)
      Himeno A, Satoh-Asahara N, Usui T, Wada H, Tochiya M, Kono S, Yamada-Goto N, Katsuura G, Hasegawa K, Nakao K, Shimatsu A
    • Journal Title

      Metabolism

      Volume: 61 Pages: 255-261

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] α1-Antitrypsin-low-density-lipoprotein Serves as a Marker of Smoking-specific Oxidative Stress2012

    • Author(s)
      Wada H, Ura S, Satoh-Asahara N, Kitaoka S, Mashiba S, Akao M, A be M, Ono K, Morimoto T, Fujita M, Shimatsu A, Takahashi Y, Hasegawa K
    • Journal Title

      J Atheroscler Thromb

      Volume: 19 Pages: 47-58

    • NAID

      130004721902

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Distinct characteristics of circulating vascular endothelial growth factor-A and C levels in human subjects2011

    • Author(s)
      Wada H, Ura S, Kitaoka S, Satoh-Asahara N, Horie T, Ono K, Takaya T, Takanabe-Mori R, Akao M, Abe M, Morimoto T, Murayama T, Yokode M, Fujita M, Shimatsu A, Hasegawa K.
    • Journal Title

      Pros ONE

      Volume: 6 Issue: 12 Pages: 29351-29351

    • DOI

      10.1371/journal.pone.0029351

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] The Japan Obesity Metabolic Syndrome Study(JOMS) Group. Serum Amyloid A Low-density Lipoprotein Levels and Smoking Status in Obese Japanese Patients2011

    • Author(s)
      Kotani K, Satoh-Asahara N, Kato Y, Araki R, Himeno A, Yamakage H, Koyama K, Tanabe T, Oishi M, Okajima T, Shimatsu A
    • Journal Title

      J Int Med Res

      Volume: 39 Pages: 1917-1922

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Characteristics of carotid plaque findings on ultrasonography and black blood magnetic resonance imaging in comparison with pathological findings2011

    • Author(s)
      Arai D, Yamaguchi S, Murakami M, Nakakuki T, Fukuda S, Satoh-Asahara N, Tsukahara T
    • Journal Title

      Acta Neurochir Suppl

      Volume: 112 Pages: 15-19

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Increased Expression of Macrophage-inducible C-type Lectin in Adipose Tissue of Obese Mice and Humans2011

    • Author(s)
      Ichioka M, Suganami T, Tsuda N, Shirakawa I, H irata Y, Satoh-Asahara N, Shimoda Y, Tanaka M, Kim-Saijo M, Miyamoto Y, Kamei Y, Sata M, Ogawa Y
    • Journal Title

      Diabetes

      Volume: 60 Pages: 15-19

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] The Japan Obesity Metabolic Syndrome Study(JOMS) Group. Urinary Cystatin C as a Potential Risk Marker for Cardiovascular Disease and Chronic Kidney Disease in Patients with Obesity and Metabolic Syndrome2011

    • Author(s)
      Satoh-Asahara N, Suga mami T, Majima T, Kotani K, Kato Y, Araki R, Koyama K, Okajima T, Tanabe M, Oishi M, Himeno A, Kono S, Sugawara A, Masakazu H, Ogawa Y, and Shimatsu A
    • Journal Title

      Clin J Am Soc Nephrol

      Volume: 6 Pages: 265-273

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Remnantt-like particle cholesterol and serum amyloid A-low-density lipoprotein levels in obese subjects with metabolic syndrome2011

    • Author(s)
      Kotani K, Satoh-Asahara N, Kato Y, Araki R, Himeno A, Yamakage H, Koyama K, Tanabe T, Oishi M, Okajima T, Shimatsu A, The Japan Obesity Metabolic Syndrome Study (JOMS) Group
    • Journal Title

      J Clin Lipidol

      Volume: 5 Pages: 395-400

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Serum Amyloid A Low-density Lipoprotein Levels and Smoking Status in Obese Japanese Patients2011

    • Author(s)
      Kotani K, Satoh-Asahara N, Kato Y, Araki R, Himeno A, Yamakage H, Koyama K, Tanabe T, Oishi M, Okajima T, Shimatsu A, The Japan Obesity Metabolic Syndrome Study (JOMS) Group
    • Journal Title

      J Int Med Res

      Volume: 39 Pages: 1917-1922

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Urinary Cystatin C as a Potential Risk Marker for Cardiovascular Disease and Chronic Kidney Disease in Patients with Obesity and Metabolic Syndrome2011

    • Author(s)
      Satoh-Asahara N, Sugamami T, Majima T, Kotani K, Kato Y, Araki R, Koyama K, Okajima T, Tanabe M, Oishi M, Himeno A, Kono S, Sugawara A, Masakazu H, Ogawa Y, Shimatsu A, The Japan Obesity Metabolic Syndrome Study (JOMS) Group
    • Journal Title

      Clin J Am Soc Nephrol

      Volume: 6 Pages: 265-273

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Increased Expression of Macrophage-inducible C-type Lectin in Adipose Tissue of Obese Mice and Humans.2011

    • Author(s)
      Ichioka M, Suganami T, Tsuda N, Shirakawa I, Hirata Y, Satoh-Asahara N, Shimoda Y, Tanaka M, Kim-Saijo M, Miyamoto Y, Kamei Y, Sata M, Ogawa Y.
    • Journal Title

      Diabetes

      Volume: 60 Pages: 819-826

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Urinary Cystatin C as a Potential Risk Marker for Cardiovascular Disease and Chronic Kidney Disease in Patients with Obesity and Metabolic Syndrome.2011

    • Author(s)
      Satoh-Asahara N, Sugamami T, Majima T, Kotani K, Kato Y, Araki R, Koyama K, Okajima T, Tanabe M, Oishi M, Himeno A, Kono S, Sugawara A, Masakazu H, Ogawa Y, Shimatsu A, The Japan Obesity Metabolic Syndrome Study (JOMS) Group.
    • Journal Title

      Clin J Am Soc Nephrol

      Volume: 6 Pages: 265-273

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] BOT長時間作動性インスリンによるBasal supported oral therapy2011

    • Author(s)
      佐藤哲子
    • Journal Title

      Journal of Integrated Medicine (JIM)

      Volume: 4 Pages: 248-250

    • Related Report
      2010 Annual Research Report
  • [Journal Article] 1、肥満の発症機構I、基礎的領域2011

    • Author(s)
      小川佳宏、佐藤哲子
    • Journal Title

      肥満と消化器疾患

      Pages: 2-14

    • Related Report
      2010 Annual Research Report
  • [Journal Article] The potential of serum amyloid A-LDL as a novel biomarker for cardiovascular disease risk2010

    • Author(s)
      Kotani K, Satoh N, Yamada T, Gugliucci A
    • Journal Title

      Clin Lipidol

      Volume: 6 Pages: 489-495

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] The influence of metabolic syndrome and chronic kidney disease on the hemorheology assessed by the microchannel method2010

    • Author(s)
      Kotani K, Satoh N, Yamada K, Taniguchi N, Shimatsu A
    • Journal Title

      J Physiol Anthropol

      Volume: 29 Pages: 157-160

    • NAID

      10026670240

    • Related Report
      2011 Final Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] High blood viscosity is closely associated with cigarette smoking and markedly reduced by smoking cessation2010

    • Author(s)
      Shimada S, Hasegawa K, Wada H, Terashima S, Satoh-Asahara N, Yamakage H, Kitaoka S, Akao M, Shimatsu A, Takahashi Y
    • Journal Title

      Circ J

      Volume: 75 Pages: 185-189

    • NAID

      10027425903

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] LOX-1 is required for the adipose tissue expression of proinflammatory cytokines in high-fat diet-induced obese mice2010

    • Author(s)
      Takanabe-Mori R, Ono K, Sowa N, Wada H, Takaya T, Horie T, Satoh-Asahara N, Shimatsu A, Fujita M, Sawamura T, Hasegawa K
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 398 Pages: 576-580

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Bezafibrate and Serum Amyloid A-low-density Lipoprotein Complex in Patients with Type 2 Diabetes Mellitus and Hypertriglyceridemia2010

    • Author(s)
      Kotani K, Satoh N, Yamada Y
    • Journal Title

      Eur J Intern Med

      Volume: 21 Pages: 10-10

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Unbalanced M1/M2 Phenotype of Peripheral Blood Monocytes in Obese Diabetic Patients : Effect of Pioglitazone2010

    • Author(s)
      Satoh N, Shimatsu A, Himeno A, Sasaki Y, Yamakage H, Yamada K, Suganami T, and Ogawa Y
    • Journal Title

      Diabetes Care

      Volume: 33 Pages: 7-7

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Soluble VEGF receptor-2 is increased in sera of subjects with metabolic syndrome in association with insulin resistance2010

    • Author(s)
      Wada H, Satoh N, Kitaoka S, Ono K, Morimoto T, Kawamura T, Nakano, T, Fujita M, Kita T, Shimatsu A, Hasegawa K
    • Journal Title

      Atherosclerosis

      Volume: 208 Pages: 512-517

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Transmitral E/A ratio decreases in association with abdominal fat accumulation in patients with impaired glucose tolerance or mild diabetes without left ventricular hypertrophy2010

    • Author(s)
      Wada H, Satoh N, Hasegawa K
    • Journal Title

      Heart Vessels

      Volume: 25 Pages: 45-50

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] High blood viscosity is closely associated with cigarette smoking and markedly reduced by smoking cessation.2010

    • Author(s)
      Shimada S, Hasegawa K, Wada H, Terashima S, Satoh-Asahara N, Yamakage H, Kitaoka S, Akao M, Shimatsu A, Takahashi Y.
    • Journal Title

      Circ J

      Volume: 75 Pages: 185-189

    • NAID

      10027425903

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The influence of metabolic syndrome and chronic kidney disease on the hemorheology assessed by the microchannel method.2010

    • Author(s)
      Takanabe-Mori R, Ono K, Sowa N, Wada H, Takaya T, Horie T, Satoh-Asahara N, Shimatsu A, Fujita M, Sawamura T, Hasegawa K.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 398 Pages: 576-580

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 肥満・メタボリックシンドロームに伴う慢性腎臓病の早期診断指標の検討-血清・尿中シスタチンCの有用性と心腎連関-2010

    • Author(s)
      佐藤哲子、島津章
    • Journal Title

      腎臓

      Volume: 33 Pages: 113-119

    • Related Report
      2010 Annual Research Report
  • [Journal Article] 飽和・不飽和脂肪酸と肥満・動脈硬化性疾患The Influence of Saturated Fatty Acid and Unsaturated Fatty Acid on Obesity and Atherosclerosis2010

    • Author(s)
      浅原(佐藤)哲子
    • Journal Title

      オレオサイエンス

      Volume: 10 Pages: 17-22

    • Related Report
      2010 Annual Research Report
  • [Journal Article] ニコチンの体重に及ぼす影響について2010

    • Author(s)
      姫野亜紀裕、佐藤哲子、小川佳宏
    • Journal Title

      内分泌・糖尿病・代謝内科

      Volume: 30 Pages: 282-286

    • NAID

      40017666367

    • Related Report
      2010 Annual Research Report
  • [Journal Article] Bezafibrate and Serum Amyloid A-low-density Lipoprotein Complex in Patients with Type 2 Diabetes Mellitus and Hypertriglyceridemia.2010

    • Author(s)
      Kotani K, Satoh N, Yamada T.
    • Journal Title

      Eur J Intern Med 21

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Unbalanced M1/M2 Phenotype of Peripheral Blood Monocytes in Obese Diabetic Patients : Effect of Pioglitazone.2010

    • Author(s)
      Satoh N, Shimatsu A, Himeno A, Sasaki Y, Yamakage H, Yamada K, Suganami T, Ogawa Y.
    • Journal Title

      Diabetes Care 33

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Soluble VEGF receptor-2 is increased in sera of subjects with metabolic syndrome in association with insulin resistance.2010

    • Author(s)
      Wada H, Satoh N, Kitaoka S, Ono K, Morimoto T, Kawamura T, Nakano, T, Fujita M, Kita T, Shimatsu A, Hasegawa K.
    • Journal Title

      Atherosclerosis 208

      Pages: 512-517

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Transmitral E/A ratio decreases in association with abdominal fat accumulation in patients with impaired glucose tolerance or mild diabetes without left ventricular hypertrophy.2010

    • Author(s)
      Wada H, Satoh N, Hasegawa K.
    • Journal Title

      Heart and Vessels 25

      Pages: 45-50

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] BOT長時間作動性インスリンによるBasal supported oral therapy2010

    • Author(s)
      佐藤哲子
    • Journal Title

      Journal of Integrated Medicine(JIM) 4

      Pages: 248-250

    • Related Report
      2009 Annual Research Report
  • [Journal Article] 1、肥満の発症機構 I、基礎的領域2010

    • Author(s)
      小川佳宏、佐藤哲子
    • Journal Title

      肥満と消化器疾患

      Pages: 2-14

    • Related Report
      2009 Annual Research Report
  • [Journal Article] メタボリック症候群とRAS阻害薬の有用性2010

    • Author(s)
      佐藤哲子
    • Journal Title

      臨床雑誌「内科」 105

      Pages: 469-475

    • Related Report
      2009 Annual Research Report
  • [Journal Article] 脂質代謝異常と心血管病~新しい病態把握をめざして~2010

    • Author(s)
      佐藤哲子
    • Journal Title

      SEASONAL POST 1

      Pages: 6-6

    • Related Report
      2009 Annual Research Report
  • [Journal Article] Highly purified eicosapentaenoic acid reduces cardio-ankle vascular index in association with decrease in serum amyloid A-LDL in metabolic syndrome.2009

    • Author(s)
      Satoh N, Shimatsu A, Kotani K, Himeno A, Majima T, Yamada K, Suganami T, Ogawa Y.
    • Journal Title

      Hypertens Res 32

      Pages: 1004-1008

    • NAID

      10026124410

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A novel oxidized low-density lipoprotein marker, serum amyloid A-LDL, is associated with obesity and the metabolic syndrome.2009

    • Author(s)
      Kotani K, Satoh N, Kato Y, Araki R, Koyama K, Okajima T, Tanabe M, Oishi M, Yamakage H, Yamada K, Hattori M, Shimatsu A.
    • Journal Title

      Atherosclerosis 204

      Pages: 526-531

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Unfavorable Blood Rheology Is Closely Associated With Arterial Stiffness in Obese Patients.2009

    • Author(s)
      Satoh N, Kotani K, Wada H, Himeno A, Shimada S, Sasaki Y, Yamada K, Shimatsu A, Hasegawa K.
    • Journal Title

      Endocr J 56

      Pages: 915-918

    • NAID

      10026915448

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Reduction in urinary excretion of neutrophil gelatinase-associated lipocal in by angiotensin receptor blocker in hypertensive patients.2009

    • Author(s)
      Kasahara M, Mori K, Satoh N, Kuwabara T, Yokoi H, Shimatsu A, Sigawara A, Mukoyama M, Nakao K.
    • Journal Title

      Nephrol Dial Transplant 24

      Pages: 2608-2609

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of risedronate or alfacalcidol on bone mineral density, bone turnover, back pain, and fractures in Japanese men with primary osteoporosis : results of a two-year strict observational study.2009

    • Author(s)
      Majima T, Shimatsu A, Komatsu Y, Satoh N, Fukao A, Ninomiya K, Matsumura T, Nakao K.
    • Journal Title

      J Bone Miner Metab 27

      Pages: 168-174

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 肥満と精神疾患2009

    • Author(s)
      佐藤哲子、姫野亜紀裕
    • Journal Title

      CLINICIAN'09 56

      Pages: 95-102

    • Related Report
      2009 Annual Research Report
  • [Journal Article] レプチン血管作動性物質-生合性、分泌、生理作用-2009

    • Author(s)
      佐藤哲子
    • Journal Title

      日本臨床増刊号 高血圧 67

      Pages: 263-267

    • Related Report
      2009 Annual Research Report
  • [Journal Article] 飽和脂肪酸と肥満・動脈硬化性疾患2009

    • Author(s)
      佐藤哲子
    • Journal Title

      The Lipid 20

      Pages: 28-33

    • Related Report
      2009 Annual Research Report
  • [Journal Article] 肥満症患者の尿酸値・尿pH心血管病リスク指標としての可能性大2009

    • Author(s)
      姫野亜紀裕、佐藤哲子
    • Journal Title

      医薬ジャーナル 45

      Pages: 2263-2263

    • Related Report
      2009 Annual Research Report
  • [Journal Article] レプチン、アディポネクチン話題のホルモン・受容体・酵素2009

    • Author(s)
      佐藤哲子、小川佳宏
    • Journal Title

      Heart View 13

      Pages: 83-91

    • Related Report
      2009 Annual Research Report
  • [Journal Article] 肥満遺伝子2009

    • Author(s)
      佐藤哲子、小川佳宏
    • Journal Title

      新しい診断と治療のABC 59

      Pages: 46-57

    • Related Report
      2009 Annual Research Report
  • [Journal Article] 脂肪細胞と血管壁のクロストーク(アディポネクチンを含めて)2009

    • Author(s)
      佐藤哲子、小川佳宏
    • Journal Title

      血管医学 10

      Pages: 25-32

    • Related Report
      2009 Annual Research Report
  • [Journal Article] ~ストレス上昇と動脈硬化の関連~唾液中コルチゾルが指標に2009

    • Author(s)
      佐藤哲子
    • Journal Title

      Medical Tribune 42

      Pages: 8-8

    • Related Report
      2009 Annual Research Report
  • [Journal Article] The Japan Obesity Metabolic Syndrome Study(JOMS) Group. Remnantt-like particle cholesterol and serum amyloid A-low-density lipoprotein levels in obese subjects with metabolic syndrome

    • Author(s)
      Kotani K, Satoh-Asahara N, Kato Y, Araki R, Himeno A, Yamakage H, Koyama K, Tanabe T, Oishi M, Okajima T, Shimatsu A
    • Journal Title

      J Clin Lipidol

      Volume: 5 Pages: 395-400

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Presentation] 生活習慣病におけるリポ蛋白の質的検査の意義2012

    • Author(s)
      浅原哲子
    • Organizer
      第22回生物試料分析科学会年次学術集会
    • Place of Presentation
      福岡(招待講演)
    • Year and Date
      2012-03-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] 頸動脈プラーク内のマクロファージ浸潤と炎症性サイトカイン発現に対する糖尿病の影響2012

    • Author(s)
      浅原哲子、村中和哉、佐々木洋介、山陰一、塚原徹也
    • Organizer
      第37回日本脳卒中学会総会
    • Place of Presentation
      福岡
    • Related Report
      2011 Final Research Report
  • [Presentation] メタボリック症候群における高脂血症薬・EPAの抗動脈硬化作用の分子機構-PPARγを介するIL-10の上昇作用-2012

    • Author(s)
      浅原哲子、佐々木洋介、橡谷真由、村中和哉、山陰一、河野茂夫、島津章
    • Organizer
      第85回日本内分泌学会学術総会
    • Place of Presentation
      愛知
    • Related Report
      2011 Final Research Report
  • [Presentation] 生活習慣病におけるリポ蛋白の質的検査の意義2012

    • Author(s)
      浅原哲子
    • Organizer
      第22回生物試料分析科学会年次学術集会(招待講演)
    • Place of Presentation
      福岡
    • Related Report
      2011 Final Research Report
  • [Presentation] 血管機能と糖尿病(1)(PWV, CAVI)2012

    • Author(s)
      浅原哲子
    • Organizer
      第46回糖尿病学の進歩(招待講演)
    • Place of Presentation
      岩手
    • Related Report
      2011 Final Research Report
  • [Presentation] 血管機能と糖尿病(1)(PWV,CAVI)2012

    • Author(s)
      浅原哲子
    • Organizer
      第46回糖尿病学の進歩
    • Place of Presentation
      岩手(招待講演)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 日本人肥満症における心腎合併症予防のためのアディポサイトカインの臨床的意義と減量治療効果に関する多施設共同研究2011

    • Author(s)
      浅原(佐藤)哲子
    • Organizer
      神戸成人血管病シンポジウム(招待講演)
    • Place of Presentation
      兵庫
    • Year and Date
      2011-12-10
    • Related Report
      2011 Final Research Report
  • [Presentation] 日本人肥満症における心腎合併症予防のためのアディポサイトカインの臨床的意義と減量治療効果に関する多施設共同研究2011

    • Author(s)
      浅原(佐藤)哲子
    • Organizer
      神戸成人血管病シンポジウム
    • Place of Presentation
      兵庫(招待講演)
    • Year and Date
      2011-12-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] 脳梗塞患者における血中アディポサイトカインの検討2011

    • Author(s)
      中久木卓也、浅原哲子、福田俊一、村上守、新井大輔、山口将、中村道三、大谷良、山陰一、塚原徹也
    • Organizer
      第36回日本脳卒中学会総会
    • Place of Presentation
      東京
    • Year and Date
      2011-07-30
    • Related Report
      2011 Annual Research Report
  • [Presentation] メタボリックシンドロームにおける心血管病リスク指標としてのCAVIの有用性と生活指導2011

    • Author(s)
      浅原哲子
    • Organizer
      第29回日本肥満症治療学会学術集会ランチョンセミナー
    • Place of Presentation
      京都(招待講演)
    • Year and Date
      2011-06-11
    • Related Report
      2011 Annual Research Report
  • [Presentation] 肥満・メタボリック症候群における単球機能を標的とした動脈硬化早期診断パネルの構築と心腎疾患予防法2011

    • Author(s)
      浅原哲子
    • Organizer
      第32回日本肥満学会学術奨励賞(招待講演)
    • Place of Presentation
      兵庫
    • Related Report
      2011 Final Research Report
  • [Presentation] 脂質代謝異常合併肥満症におけるEPAによる末梢血単球M1/M2タイプへの影響と抗動脈硬化作用2011

    • Author(s)
      浅原哲子、佐々木洋介、橡谷真由、姫野亜紀裕、村中和哉、山陰一、小鳥真司、河野茂夫、和田啓道、長谷川浩二、島津章
    • Organizer
      第32回日本肥満学会
    • Place of Presentation
      兵庫
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 肥満・2型糖尿病患者における末梢血単球M1/M2タイプに対するピオグリタゾンの効果2011

    • Author(s)
      佐々木洋介、浅原哲子、村中和哉、橡谷真由、姫野亜紀裕、山陰一、河野茂夫、島津章
    • Organizer
      第32回日本肥満学会
    • Place of Presentation
      兵庫
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] メタボリックシンドロームにおける心血管病リスク指標としてのCAVIの有用性と生活指導2011

    • Author(s)
      浅原哲子
    • Organizer
      第29回日本肥満症治療学会学術集会ランチョンセミナー(招待講演)
    • Place of Presentation
      京都
    • Related Report
      2011 Final Research Report
  • [Presentation] 肥満・メタボリック症候群におけるエイコサペンタエン酸による末梢血単球M1/M2タイプへの影響と抗動脈硬化作用2011

    • Author(s)
      浅原哲子、佐々木洋介、橡谷真由、姫野亜紀裕、村中和哉、山陰一、河野茂夫、島津章
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      北海道
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] Soluble LOX-1 and LOX Index in Sera of Smoking Patients are Closely Associated with Highly Sensitive CRP and Expired Air Carbon Monoxide Concentrations2011

    • Author(s)
      Takanabe-Mori R, Ono K, Wada H, Takaya T, Yamakage H, Satoh-Asahara N, Shimatsu A, Takahashi Y, Fujita M, Fujita Y, Sawamura T, Hasegawa K
    • Organizer
      American Heart Association Scientific Sessions 2011
    • Place of Presentation
      Florida
    • Related Report
      2011 Annual Research Report
  • [Presentation] Amylin has an antidepressant action in diet-induced obesity2011

    • Author(s)
      Yamada-Goto N, Katsuura G, Ochi Y, Ebihara K, Kusakabe T, Satoh-Asahara N, Hosoda K, Nakao K
    • Organizer
      OBESITY 2011 29^<th> Annual Scientific Meeting
    • Place of Presentation
      Florida
    • Related Report
      2011 Annual Research Report
  • [Presentation] 肥満・メタボリック症候群における単球機能を標的とした動脈硬化早期診断パネルの構築と心腎疾患予防法2011

    • Author(s)
      浅原哲子
    • Organizer
      第32回日本肥満学会学術奨励賞
    • Place of Presentation
      兵庫(招待講演)
    • Related Report
      2011 Annual Research Report
  • [Presentation] ヒト血中の血管内皮増殖因子A(VEGF-A)及びC(VEGF-C)の心血管危険因子との関連2011

    • Author(s)
      浦修一、和田啓道、北岡修二、浅原哲子、高谷智英、森利依子、赤尾昌治、阿部充、森本達也、尾野亘、藤田正俊、島津章、長谷川浩二
    • Organizer
      第32回日本肥満学会
    • Place of Presentation
      兵庫
    • Related Report
      2011 Annual Research Report
  • [Presentation] 肥満症・メタボリック症候群における睡眠時無呼吸症候群の重症度と心血管病リスクとの関連2011

    • Author(s)
      井口梓、山陰一、橡谷真由、村中和哉、佐々木洋介、島津章、河野茂夫、浅原哲子
    • Organizer
      第32回日本肥満学会
    • Place of Presentation
      兵庫
    • Related Report
      2011 Annual Research Report
  • [Presentation] 高脂肪食または高炭水化物食負荷がもたらす糖脂質代謝異常の差異の検討2011

    • Author(s)
      姫野亜紀裕、浅原哲子、佐々木洋介、村中和哉、後藤伸子、田中智洋、橡谷真由、勝浦五郎、中尾一和、島津章
    • Organizer
      第32回日本肥満学会
    • Place of Presentation
      兵庫
    • Related Report
      2011 Annual Research Report
  • [Presentation] チロシンフォスファターゼ1B遺伝子多型は日本人の肥満発症及び減量治療抵抗性に関与する2011

    • Author(s)
      宮永史子、浅原哲子、森崎裕子、山中到、小久保喜弘、宮本恵宏、森崎隆幸、島津章
    • Organizer
      第32回日本肥満学会
    • Place of Presentation
      兵庫
    • Related Report
      2011 Annual Research Report
  • [Presentation] 橡谷真由、浅原哲子、姫野亜紀裕、村中和哉、佐々木洋介、山陰一、河野茂夫、岡嶋泰一郎、田邊真紀人、加藤泰久、荒木里香、大石まり子、小谷和彦、島津章:日本人肥満症の減量成功とリバウンドに関する検討-NHO肥満症多施設共同研究(JOMS)-2011

    • Author(s)
      橡谷真由、浅原哲子、姫野亜紀裕、村中和哉、佐々木洋介、山陰一、河野茂夫、岡嶋泰一郎、田邊真紀人、加藤泰久、荒木里香、大石まり子、小谷和彦、島津章
    • Organizer
      第32回日本肥満学会
    • Place of Presentation
      兵庫
    • Related Report
      2011 Annual Research Report
  • [Presentation] 胎盤由来増殖因子(PIGF)は禁煙後の内臓脂肪蓄積、インスリン抵抗性憎悪を鋭敏に反映する2011

    • Author(s)
      山田明、和田啓道、浦修一、北岡修二、浅原(佐藤)哲子、高谷智英、森(高鍋)利依子、赤尾昌治、森本達也、藤田正俊、高橋裕子、島津章、長谷川浩二
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      北海道
    • Related Report
      2011 Annual Research Report
  • [Presentation] 肥満症・メタボリック症候群における睡眠時無呼吸の実態と減量効果-アディポサイトカインや動脈硬化指標との関連-2011

    • Author(s)
      井口梓、浅原哲子、山陰一、橡谷真由、村中和哉、佐々木洋介、島津章、河野茂夫
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      北海道
    • Related Report
      2011 Annual Research Report
  • [Presentation] 肥満症治療における減量成功およびリバウンドに対する抑うつ状態の関与2011

    • Author(s)
      橡谷真由、浅原哲子、姫野亜紀裕、村中和哉、佐々木洋介、山陰一、島津章、河野茂夫
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      北海道
    • Related Report
      2011 Annual Research Report
  • [Presentation] 血管内皮増殖因子C(VEGF-C)はメタボリックシンドロームで上昇し、脂質異常、可溶性VEGF受容体2に関連する2011

    • Author(s)
      浦修一、和田啓道、山田明、北岡修二、浅原(佐藤)哲子、高谷智英、森(高鍋)利依子、赤尾昌治、阿部充、森本達也、藤田正俊、島津章、長谷川浩二
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      北海道
    • Related Report
      2011 Annual Research Report
  • [Presentation] プラバスタチンもしくはアトルバスタチンとロサルタンの併用が耐糖能患者の初期腎病変に及ぼす影響2011

    • Author(s)
      和田啓道、尾野亘、浅原(佐藤)哲子、川村晃久、森本達也、上北和実、東堂龍平、山田和範、赤尾昌治、小坂田元太、島津章、長谷川浩二
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      北海道
    • Related Report
      2011 Annual Research Report
  • [Presentation] 高脂肪食または高炭水化物食負荷によるメタボリックパラメータの変化-エネルギー組成の差異がもたらす糖脂質代謝異常の検討-2011

    • Author(s)
      姫野亜紀裕、浅原哲子、田中智洋、佐々木洋介、村中和哉、橡谷真由、山田伸子、勝浦五郎、中尾一和、島津章
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      北海道
    • Related Report
      2011 Annual Research Report
  • [Presentation] 日本人の肥満発症及び減量治療抵抗性に関連する遺伝素因の探索-チロシンホスファクーゼIB遺伝子多型の検討-2011

    • Author(s)
      宮永史子、浅原哲子、森崎裕子、山中到、小久保善弘、宮本恵宏、島津章、森崎隆幸
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      北海道
    • Related Report
      2011 Annual Research Report
  • [Presentation] Serum Soluble LOX-1 Levels are Increased in Close Association With hsCRP Levels and Expired Air CO Concentrations in Smokers2011

    • Author(s)
      Takanabe-Mori R, Ono K, Wada H, Takaya T, Yamakage H, Satoh-Asahara N, Shimatsu A, Takahashi Y, Fujita M, Fujita Y, Sawamura T, Hasegawa K
    • Organizer
      The 14th Annual INTERNATIONAL TORONTO HEART SUMMIT Together with the ISCHF A Member of the World Heart Federation
    • Place of Presentation
      Toronto, Canada
    • Related Report
      2011 Annual Research Report
  • [Presentation] 肥満・メタボリック症候群におけるHPA axis activityの異常と心血管病リスクとの関連-唾液コルチゾールの検討-2011

    • Author(s)
      浅原哲子、臼井健、橡谷真由、姫野亜紀裕、河野茂夫、島津章
    • Organizer
      第84回日本内分泌学会学術総会
    • Place of Presentation
      兵庫県
    • Related Report
      2011 Annual Research Report
  • [Presentation] 日本人の肥満発症及び減量効果の遺伝素因の探索-PTP1Bの影響-2011

    • Author(s)
      宮永史子、浅原哲子、森崎裕子、山中到、小久保喜弘、宮本恵宏、森崎隆幸、島津章
    • Organizer
      第84回日本内分泌学会学術総会
    • Place of Presentation
      兵庫県
    • Related Report
      2011 Annual Research Report
  • [Presentation] Effect of pioglitazone on unbalanced M1/M2 phenotype of peripheral blood monocytes in obese diabetic patients.2010

    • Author(s)
      Satoh-Asahara N, Himeno A, Sasaki Y, Yamada K, Suganami T, Ogawa Y, Shimatsu A
    • Organizer
      14th International Congress of Endocrinology(ICE2010)Poster Session of the official Satelite Symposia "Obesity and Metabolic Syndrome"
    • Place of Presentation
      京都
    • Year and Date
      2010-03-31
    • Related Report
      2009 Annual Research Report
  • [Presentation] The association of salivary cortisol with cardiovascular risks and efficacy of weight reduction therapy in obese patients.2010

    • Author(s)
      Himeno A, Satoh N, Usui T, Wada H, Yamada K, Yamada N, Hasegawa K, Shimatsu A, Katsuura G, Nakao K.
    • Organizer
      14th International Congress of Endocrinology(ICE2010)
    • Place of Presentation
      京都
    • Year and Date
      2010-03-30
    • Related Report
      2009 Annual Research Report
  • [Presentation] Angiotensin receptor blocker(ARB)reduces urinary concentrations of neutrophil gelatinase-associated lipocalin(Ngal)in diabetes and obesity.2010

    • Author(s)
      Kasahara M, Mori K, Kuwabara T, Satoh N, Yokoi H, Saito Y, mamaki H, Nagae T, Ogawa Y, Kawanishi T, Shimatsu A, Sugawara A, Mukoyama M, Nakao K.
    • Organizer
      14th International Congress of Endocrinology(ICE2010)
    • Place of Presentation
      京都
    • Year and Date
      2010-03-28
    • Related Report
      2009 Annual Research Report
  • [Presentation] Effect of Pioglitazone on Unfavorable M1/M2 Phenotype of Peripheral Blood Monocytes in Obese Diabetic Patients.2010

    • Author(s)
      Satoh-Asahara N, Himeno A, Tochiya M, Sasaki Y, Yamada K, Suganami T, Ogawa T, Shimatsu A
    • Organizer
      14th International Congress of Endocrinology(ICE2010)
    • Place of Presentation
      京都
    • Year and Date
      2010-03-27
    • Related Report
      2009 Annual Research Report
  • [Presentation] 肥満合併糖尿病における心血管病リスク指標としての末梢血単球M1/M2サブセットの検討-インスリン抵抗性改善薬の効果-2010

    • Author(s)
      佐藤哲子、姫野亜紀裕、佐々木洋介、山田和範、小川佳宏、菅波孝祥、島津章
    • Organizer
      第83回日本内分泌学会年次学術集会
    • Place of Presentation
      京都
    • Year and Date
      2010-03-26
    • Related Report
      2009 Annual Research Report
  • [Presentation] 肥満・メタボリック症候群における唾液コルチゾール濃度の病態生理学的意義の検討2010

    • Author(s)
      姫野亜紀裕、佐藤哲子、臼井健、山田和範、島津章、山田伸子、勝浦五郎、中尾一和
    • Organizer
      第83回日本内分泌学会年次学術集会
    • Place of Presentation
      京都
    • Year and Date
      2010-03-26
    • Related Report
      2009 Annual Research Report
  • [Presentation] The Mechanisms Reducing Acute Coronary Syndrome Following a Smoking Ban : A Possible Novel Biomarker of Smoking-specific Oxidative Stress.2010

    • Author(s)
      Hiromichi Wada, Noriko Satoh, Shuji Kitaoka, Masaharu Akao, Akira Shimatsu, Koji Hasegawa.
    • Organizer
      The 74th Annual Scientific Meeting of the Japanese Circulation Society
    • Place of Presentation
      京都
    • Year and Date
      2010-03-07
    • Related Report
      2009 Annual Research Report
  • [Presentation] Roles of Lectin-like Oxidized Low-density Lipoprotein Receptor-1 for Glucose Tplerance in Normal and Obese Mice.2010

    • Author(s)
      Reiko Takanabe-Mori, Koh Ono, Naoya Sowa, Hiromichi Wada, Tomohide Takaya, Noriko Satoh, Akira Shimatsu, Masatoshi Fujita, Tatsuya Sawamura, Koji Hasegawa.
    • Organizer
      The 74th Annual Scientific Meeting of the Japanese Circulation Society
    • Place of Presentation
      京都
    • Year and Date
      2010-03-07
    • Related Report
      2009 Annual Research Report
  • [Presentation] Placental Growth Factor is a Sensitive Indicator of a Weight Gain after Successful Smoking Cessation.2010

    • Author(s)
      Hiromichi Wada, Noriko Satoh, Shuichi Ura, Akira Yamada, Masaharu Akao, Mitsura Abe, Junko Funatsu, Hisahi Ogawa, Maki Nishio, Masatoshi Fujita, Akira Shimatsu, Koji Hasegawa.
    • Organizer
      The 74th Annual Scientific Meeting of the Japanese Circulation Society
    • Place of Presentation
      京都
    • Year and Date
      2010-03-07
    • Related Report
      2009 Annual Research Report
  • [Presentation] Serum Levels of α1-Antitrypsin-LDL are Negatively Associated with Soluble VEGF Receptor-1 in Smokers and Decrease after Successful Smoking Cessation.2010

    • Author(s)
      Hiromichi Wada, Noriko Satoh, Shuji Kitaoka, Shuichi Ura, Akira Yamada, Masaharu Akao, Mitsuru Abe, Hunko Funatsu, Hisashi Ogawa, Maki Nishio, Masatoshi Fujita, Akira Shimatsu, Koji Hasegawa.
    • Organizer
      The 74th Annual Scientific Meeting of the Japanese Circulation Society
    • Place of Presentation
      京都
    • Year and Date
      2010-03-07
    • Related Report
      2009 Annual Research Report
  • [Presentation] High Blood Viscosity is Closely Associated with Cigarette Smoking and Markedly Reduced by Smoking Cession.2010

    • Author(s)
      Sayaka Shimada, Koji Hasegawa, Hiromichi Wada, Noriko Satoh, Sachiko Terashima, Akira Shimatsu, Yuko Takahashi.
    • Organizer
      The 74th Annual Scientific Meeting of the Japanese Circulation Society
    • Place of Presentation
      京都
    • Year and Date
      2010-03-07
    • Related Report
      2009 Annual Research Report
  • [Presentation] Soluble VEGF Receptor-2 is a Possible Novel Indicator of Impaired Angiogenesis in Metabolic Syndrome.2010

    • Author(s)
      Hiromichi Wada, Noriko Satoh, Shuji Kitaoka, Ko Ono, Tatsuya Morimoto, Teruhisa Kawamura, Tameo Nakano, Masatoshi Fujita, Toru Kita, Akira Shimatsu, Koji Hasegawa.
    • Organizer
      The 74th Annual Scientific Meeting of the Japanese Circulation Society
    • Place of Presentation
      京都
    • Year and Date
      2010-03-07
    • Related Report
      2009 Annual Research Report
  • [Presentation] Smoking, Depressive Mood and Cardiovascular Events.2010

    • Author(s)
      Koji Hasegawa, Hiromichi Wada, Noriko Satoh, Sachiko Terashima, Sayaka Shimada, Akira Shimatsu, Yuko Takahashi.
    • Organizer
      The 74th Annual Scientific Meeting of the Japanese Circulation Society
    • Place of Presentation
      京都
    • Year and Date
      2010-03-06
    • Related Report
      2009 Annual Research Report
  • [Presentation] LOX-1 is Required for Overexpression of MCP-1 in Mesenteric Fat Tissue of Obese Mice.2010

    • Author(s)
      Reiko Takanabe-Mori, Koh Ono, Naoya Sowa, Hiromichi Wada, Tomohide Takaya, Noriko Satoh, Akira Shimatsu, Masatoshi Fujita, Tatsuya Sawamura, Koji Hasegawa.
    • Organizer
      The 74th Annual Scientific Meeting of the Japanese Circulation Society
    • Place of Presentation
      京都
    • Year and Date
      2010-03-06
    • Related Report
      2009 Annual Research Report
  • [Presentation] Vascular Endothelial Growth Factor-C is Increased in Patients with Met S in Close Association with Blood Pressure.2010

    • Author(s)
      Hiromichi Wada, Noriko Satoh, Shuji Kitaoka, Shuichi Ura, Akira Yamada, Masaharu Akao, Mitsuru Abe, Junko Funatsu, Hisahi Ogawa, Maki Nishio, Masatoshi Fujita, Akira Shimatsu, Koji Hasegawa.
    • Organizer
      The 74th Annual Scientific Meeting of the Japanese Circulation Society
    • Place of Presentation
      京都
    • Year and Date
      2010-03-06
    • Related Report
      2009 Annual Research Report
  • [Presentation] Salivary Cortisol Is Related to Coronary Heart Disease Risk.2010

    • Author(s)
      Hiromichi Wada, Koji Hasegawa, Takeshi Usui, Sachiko Terashima, Noriko Satoh, Akihiro Himeno, Yuko Iida, Akira Yamada, Shuichi Ura, Shuji Kitaoka, Masaharu Akao, Mitsuru Abe, Masatoshi Fujita, Akira Shimatsu, Yuko Takahashi.
    • Organizer
      The 74th Annual Scientific Meeting of the Japanese Circulation Society
    • Place of Presentation
      京都
    • Year and Date
      2010-03-06
    • Related Report
      2009 Annual Research Report
  • [Presentation] 肥満・2型糖尿病の心血管病リスクとしての末梢血単球M1/M2タイプの意義とピオグリタゾンの効果2010

    • Author(s)
      浅原-佐藤哲子、橡谷真由、山田和範、島津章
    • Organizer
      第31回日本肥満学会
    • Place of Presentation
      群馬
    • Related Report
      2011 Final Research Report
  • [Presentation] 肥満・メタボリック症候群の末梢血単球M1/M2タイプに対するエイコサペンタエン酸の効果2010

    • Author(s)
      浅原(佐藤)哲子、姫野亜紀裕、橡谷真由、島津章
    • Organizer
      第3回日本肥満症治療学会学術集会
    • Place of Presentation
      東京
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] 肥満・メタボリック症候群の末梢血単球M1/M2タイプに対するエイコサペンタエン酸の効果2010

    • Author(s)
      佐々木洋介、佐藤哲子、姫野亜紀裕、橡谷真由、村中和哉、山田和範、菅波孝祥、小川佳宏、島津章
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] 肥満・2型糖尿病の心血管病リスクとしての末梢血単球M1/M2 phenotypeの病態意義の検討-ピオグリタゾンの効果-2010

    • Author(s)
      佐藤哲子、姫野亜紀裕、橡谷真由、佐々木洋介、村中和哉、山田和範、菅波孝祥、小川佳宏、島津章
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山
    • Related Report
      2011 Final Research Report
  • [Presentation] 肥満・2型糖尿病の心血管病リスクとしての末梢血単球M1/M2タイプの意義とピオグリタゾンの効果2010

    • Author(s)
      浅原-佐藤哲子、橡谷真由、山田和範、島津章
    • Organizer
      第31回日本肥満学会
    • Place of Presentation
      群馬県
    • Related Report
      2010 Annual Research Report
  • [Presentation] 肥満症における大豆イソフラボン代謝物・エクオールの生産能とエクオール投与の効果2010

    • Author(s)
      橡谷真由、浅原-佐藤哲子、臼井健、姫野亜紀裕、山田和範、島津章、上野友美、内山成人
    • Organizer
      第31回日本肥満学会
    • Place of Presentation
      群馬県
    • Related Report
      2010 Annual Research Report
  • [Presentation] 血管内皮増殖因子C(VEGF-C)はメタボリックシンドロームで上昇している2010

    • Author(s)
      和田啓道、北岡修二、浅原哲子、高谷智英、森利依子、赤尾昌治、阿部充、森本達也、藤田正俊、島津章、長谷川浩二
    • Organizer
      第31回日本肥満学会
    • Place of Presentation
      群馬県
    • Related Report
      2010 Annual Research Report
  • [Presentation] 血清α1-Antitrypsin-LDLは可溶性VEGF受容体1と逆相関し、禁煙成功後に低下する2010

    • Author(s)
      和田啓道、浅原哲子、北岡修二、浦修一、山田明、赤尾昌治、阿部充、森本達也、藤田正俊、高橋裕子、島津章、長谷川浩二
    • Organizer
      第31回日本肥満学会
    • Place of Presentation
      群馬県
    • Related Report
      2010 Annual Research Report
  • [Presentation] 胎盤由来増殖因子(PIGF)は禁煙後の体重増加と関連する2010

    • Author(s)
      和田啓道、浅原哲子、北岡修二、浦修一、山田明、赤尾昌治、阿部充、森本達也、藤田正俊、高橋裕子、島津章、長谷川浩二
    • Organizer
      第31回日本肥満学会
    • Place of Presentation
      群馬県
    • Related Report
      2010 Annual Research Report
  • [Presentation] 健常成人における可溶性血管内皮増殖因子受容体2の血清レベルはインスリン抵抗性に規定される2010

    • Author(s)
      和田啓道、佐藤哲子、北岡修二、尾野亘、森本達也、川村晃久、中野為夫、藤田正俊、北徹、島津章、長谷川浩二
    • Organizer
      第31回日本肥満学会
    • Place of Presentation
      群馬県
    • Related Report
      2010 Annual Research Report
  • [Presentation] The effect of equol on obesity and metabolic syndrome in Japanese, from the standpoint of gender and equol producing capability2010

    • Author(s)
      Usui T, Satoh-Asahara N, Inagura A, Ueno T, Uchiyama S
    • Organizer
      9th International Symposium on the Role of Soy in Health Promotion and Chronic Disease Prevention and Treatment.
    • Place of Presentation
      Wahington DC
    • Related Report
      2010 Annual Research Report
  • [Presentation] Character of Cerebral Accompanied with Metabolic Syndrome and Diabetes Mellitus.2010

    • Author(s)
      Tsukahara T, Sato N, Otani R, Nakakuki T.
    • Organizer
      7th World Stroke Congress
    • Place of Presentation
      Seoul、Korea
    • Related Report
      2010 Annual Research Report
  • [Presentation] 肥満・メタボリック症候群における大豆イソフラボン代謝物・エクオール産生能とエクオール投与の効果2010

    • Author(s)
      橡谷真由、浅原(佐藤)哲子、臼井健、姫野亜紀裕、上野友美、内山成人、島津章
    • Organizer
      第3回日本肥満症治療学会学術集会
    • Place of Presentation
      東京
    • Related Report
      2010 Annual Research Report
  • [Presentation] 臍レベルにおける腹筋の断面積は減量治療の予測指標となる2010

    • Author(s)
      姫野亜紀裕、佐藤哲子、橡谷真由、横江巧也、山陰一、佐々木洋介、村中和哉、山田和範、島津章
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山
    • Related Report
      2010 Annual Research Report
  • [Presentation] 肥満・2型糖尿病の心血管病リスクとしての末梢血単球M1/M2 phenotypeの病態意義の検討-ピオグリタゾンの効果2010

    • Author(s)
      佐藤哲子、姫野亜紀裕、橡谷真由、佐々木洋介、村中和哉、山田和範、菅波孝祥、小川佳宏、島津章
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山
    • Related Report
      2010 Annual Research Report
  • [Presentation] 水溶性もしくは脂溶性スタチンとアンジオテンシン受容体拮抗薬の併用が生活習慣病患者の耐糖能に及ぼす影響2010

    • Author(s)
      和田啓道、尾野亘、佐藤哲子、川村晃久、森本達也、上北和実、東堂龍平、山田和範、赤尾昌治、小坂田元太、島津章、長谷川浩二
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山
    • Related Report
      2010 Annual Research Report
  • [Presentation] Pioglitazone Improves Unbalanced M1/M2 Phenotypes of Peripheral Blood Monocytes in Obese Diabetic Patients2010

    • Author(s)
      Satoh-Asahara N, Sasaki Y, Muranaka K, Yamada K, Suganami T, Ogawa Y, Shimatsu A
    • Organizer
      The 14^<th> Scientific Session of the Society of Cardiovascular Endocrinology and Metabolism
    • Place of Presentation
      奈良
    • Related Report
      2010 Annual Research Report
  • [Presentation] 肥満症の減量成功率とその心腎連関改善効果-国立病院機構肥満症多施設共同研究(JOMS)-2009

    • Author(s)
      佐藤哲子、真嶋隆文、姫野亜紀裕、小谷和彦、加藤泰久、荒木里香、小山一憲、岡嶋泰一郎、田邉真紀人、大石まり子、菅原照、山田和範、服部正和、島津章
    • Organizer
      第30回日本肥満学会
    • Place of Presentation
      静岡
    • Year and Date
      2009-10-10
    • Related Report
      2009 Annual Research Report
  • [Presentation] sd-LDL, SAA-LDLと心血管病リスク-国立病院機構肥満症多施設共同肥満症研究(JOMS研究)-2009

    • Author(s)
      佐藤哲子
    • Organizer
      第24回日本糖尿病合併症学会
    • Place of Presentation
      岡山
    • Year and Date
      2009-10-10
    • Related Report
      2009 Annual Research Report
  • [Presentation] 肥満症のHPA axis活性と心血管病リスクとの関連-唾液コルチゾールとCAVIの検討-2009

    • Author(s)
      佐々木洋介、佐藤哲子、姫野亜紀裕、臼井健、和田啓道、長谷川浩二、島津章
    • Organizer
      第30回日本肥満学会
    • Place of Presentation
      静岡
    • Year and Date
      2009-10-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] 肥満症における摂取栄養素の特徴とアディポネクチンの関連-簡易食物摂取調査票の解析-2009

    • Author(s)
      大幸聡子、高木洋子、井上聡子、姫野亜紀裕、島津章、風間敬一、佐藤哲子
    • Organizer
      第30回日本肥満学会
    • Place of Presentation
      静岡
    • Year and Date
      2009-10-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] 肥満メタボリックシンドローム外来患者における食事・体重記録の指導による減量効果2009

    • Author(s)
      中西由枝、小久保敦子、小島紗耶香、高原梨沙、小峰圭子、小林美保、寺倉智子、佐藤哲子
    • Organizer
      第30回日本肥満学会
    • Place of Presentation
      静岡
    • Year and Date
      2009-10-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] 新規カンナビノイド受容体GPR55受容体の発現分布と肥満モデルマウスにおける検討2009

    • Author(s)
      姫野亜紀裕、佐藤哲子、佐々木洋介、村中和哉、島津章、山田伸子、勝浦五郎、中尾一和、山田和範
    • Organizer
      第30回日本肥満学会
    • Place of Presentation
      静岡
    • Year and Date
      2009-10-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] 肥満・メタボリックシンドロームにおけるCAVIの有用性2009

    • Author(s)
      姫野亜紀裕、山田和範、島津章、佐藤哲子
    • Organizer
      第2回日本肥満症治療学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2009-07-11
    • Related Report
      2009 Annual Research Report
  • [Presentation] 肥満症における摂取栄養素の特徴とアディポネクチンの関連-簡易食物摂取調査票の解析.2009

    • Author(s)
      大幸聡子、高木洋子、井上聡子、姫野亜紀裕、山田和範、島津章、風間敬一、佐藤哲子
    • Organizer
      第2回日本肥満症治療学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2009-07-10
    • Related Report
      2009 Annual Research Report
  • [Presentation] 肥満あるいは糖尿病を有する高血圧患者におけるARB投与は尿中Ngalおよびアルブミンを低下させる.2009

    • Author(s)
      森潔、桑原孝成、向山政志、笠原正登、横井秀基、佐藤哲子、齋藤陽子、今牧博貴、小川喜久、川西智子、菅原照、中尾一和
    • Organizer
      第52回日本腎臓学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2009-06-03
    • Related Report
      2009 Annual Research Report
  • [Presentation] 新規カンナビノイド受容体GPR55受容体の発現分布と肥満モデルマウスにおける検討.2009

    • Author(s)
      姫野亜紀裕、佐藤哲子、佐々木洋介、村中和哉、島津章、山田伸子、勝浦五郎、中尾一和、山田和範
    • Organizer
      第52回日本糖尿病学会
    • Place of Presentation
      大阪
    • Year and Date
      2009-05-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] 肥満・メタボリック症候群の動脈硬化進展(脂肪血管連関)におけるレプチン/アディポネクチン比と心臓足首血管指数(CAVI).2009

    • Author(s)
      佐々木洋介、佐藤哲子、姫野亜紀裕、山陰一、村中和哉、山田和範、島津章
    • Organizer
      第52回日本糖尿病学会
    • Place of Presentation
      大阪
    • Year and Date
      2009-05-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] 肥満症・メタボリック症候群における心血管病リスクと血清シスタチンC-国立病院機構肥満症多施設共同研究(JOMS)-2009

    • Author(s)
      佐藤哲子、真嶋隆文、姫野亜紀裕、小谷和彦、加藤泰久、荒木里香、小山一憲、岡嶋泰一郎、田邉真紀人、大石まり子、菅原照、山田和範、服部正和、島津章
    • Organizer
      第52回日本糖尿病学会
    • Place of Presentation
      大阪
    • Year and Date
      2009-05-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] ヒトおよびマウス糖尿病性腎症における尿中Ngalに対するアンギオテンシン受容体拮抗薬の効果.2009

    • Author(s)
      森潔、桑原孝成、向山政志、佐藤哲子、笠原正登、横井秀基、齋藤陽子、小川喜久、今牧博貴、川西智子、菅原照、中尾一和
    • Organizer
      第52回日本糖尿病学会
    • Place of Presentation
      大阪
    • Year and Date
      2009-05-23
    • Related Report
      2009 Annual Research Report
  • [Presentation] 左室肥大のない耐糖能異常・軽度糖尿病患者において拡張障害の指標、増帽弁E/A比は内臓脂肪蓄積に相関して低下している.2009

    • Author(s)
      和田啓道、尾野亘、佐藤哲子、森本達也、小阪田源太、中野為夫、藤田正俊、島津章、長谷川浩二
    • Organizer
      第52回日本糖尿病学会
    • Place of Presentation
      大阪
    • Year and Date
      2009-05-23
    • Related Report
      2009 Annual Research Report
  • [Presentation] 肥満症における心血管病リスクとしてのsd-LDLとSAA-LDL-国立病院機構肥満症多施設共同研究(JOMS)-2009

    • Author(s)
      山陰一、佐藤哲子、姫野亜紀裕、小谷和彦、加藤泰久、荒木里香、小山一憲、岡嶋泰一郎、田邉真紀人、大石まり子、山田和範、服部正和、島津章
    • Organizer
      第52回日本糖尿病学会
    • Place of Presentation
      大阪
    • Year and Date
      2009-05-22
    • Related Report
      2009 Annual Research Report
  • [Presentation] 肥満・メタボリック症候群における摂取栄養素の特徴とアディポネクチンの関連.2009

    • Author(s)
      高木洋子、大幸聡子、井上聡子、姫野亜紀裕、山田和範、島津章、風間敬一、佐藤哲子
    • Organizer
      第52回日本糖尿病学会
    • Place of Presentation
      大阪
    • Year and Date
      2009-05-22
    • Related Report
      2009 Annual Research Report
  • [Presentation] 肥満症における動脈硬化進展及び治療評価指標としてのレプチン・アディポネクチンの有用性-脂肪血管連関-2009

    • Author(s)
      佐藤哲子
    • Organizer
      第82回日本内分泌学会学術総会
    • Place of Presentation
      群馬
    • Year and Date
      2009-04-24
    • Related Report
      2009 Annual Research Report
  • [Book] メタボリックシンドロームの病態診断メタボリックシンドロームの臨床マーカー-病態における意義-レプチン、高分子量アディポネクチン2011

    • Author(s)
      浅原(佐藤)哲子
    • Related Report
      2011 Final Research Report
  • [Book] 魚油とω3多価不飽和脂肪酸2011

    • Author(s)
      浅原(佐藤)哲子
    • Publisher
      日本抗加齢医学会
    • Related Report
      2011 Final Research Report
  • [Book] 動脈硬化症の危険因子動脈硬化症一次予防から二次予防までメタボリックシンドローム2011

    • Author(s)
      浅原哲子、小川佳宏
    • Related Report
      2011 Final Research Report
  • [Book] メタボリックシンドロームの新知見と未来展望我が国のメタボリックシンドロームの実際-国立病院機構多施設共同研究と肥満・メタボリックシンドローム外来10年の実績から-2011

    • Author(s)
      浅原(佐藤)哲子
    • Publisher
      メディカルビューポイント
    • Related Report
      2011 Final Research Report
  • [Book] 飽和・不飽和脂肪酸と肥満・動脈硬化性疾患The Influence of Saturated Fatty Acid and Unsaturated Fatty Acid on Obesity and Atherosclerosis2010

    • Author(s)
      浅原(佐藤)哲子
    • Publisher
      オレオサイエンス
    • Related Report
      2011 Final Research Report
  • [Book] 脂質代謝異常と心血管病~新しい病態把握をめざして~2010

    • Author(s)
      佐藤哲子
    • Total Pages
      6
    • Publisher
      SEASONAL POST
    • Related Report
      2011 Final Research Report
  • [Book] チームで撲滅!メタボリックシンドローム2009

    • Author(s)
      佐藤哲子
    • Total Pages
      183
    • Publisher
      診断と治療社
    • Related Report
      2009 Annual Research Report
  • [Remarks]

    • Related Report
      2011 Final Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

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