Primary Infection with Helicobacter pylori in Japanese Kindergarten Children
| Project/Area Number |
21590720
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Public health/Health science
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| Research Institution | THE NIPPON DENTAL UNIVERSITY COLLEGE AT NIIGATA |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
WATANABE Takuya 日本歯科大学, 新潟生命歯学部, 准教授 (00440066)
HASEGAWA Katsuhiko 日本歯科大学, 新潟生命歯学部, 准教授 (60328870)
YAMAWAKI Toshihiro 日本歯科大学, 新潟生命歯学部, 助教 (00508492)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
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| Keywords | 感染症 / ピロリ菌(H. pylori) / 口腔衛生 / 幼児 / ピロリ菌(H.pylori) |
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| Research Abstract |
For the purpose of estimating the timing of primary infections by H. pylori, H. pylori DNA in saliva of kindergartners and their parent was detected. An infection rate of H. pylori tended to go up with age, and was significantly different between 4-and 5-years-old. Furthermore, H. pylori-positivity rates for the mothers of children who were H. pylori-positive were significantly higher than the mothers of H. pylori-negative children. These findings support the notion that primary infection occurs in children under 3 years of age, and the risk of H. pylori infection may be high in the children at 4-5 years. In addition, the fact that rates of H. pylori positivity are high in the mothers of H. pylori-positive children suggests that infection to a child from a mother is the most important factor.
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Report
(4 results)
Research Products
(6 results)
