Project/Area Number |
21590739
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Legal medicine
|
Research Institution | Yokohama City University |
Principal Investigator |
|
Co-Investigator(Kenkyū-buntansha) |
NISHIMURA Akiyoshi 徳島大学, ヘルスバイオサイエンス研究部, 教授 (60283561)
|
Co-Investigator(Renkei-kenkyūsha) |
NAMBU Saori 横浜市立大学, 医学部, 助教 (10404998)
AOMURA Shigeru 首都大学東京, システムデザイン学部, 教授 (20281248)
|
Project Period (FY) |
2009 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
|
Keywords | 法医学 / Shaken Baby Syndrome / 外傷性脳損傷 / ゼラチンモデル / シミュレーションモデル / ひずみゲージ / 有限要素法 / 光学的応力解析法 / Shaken baby syndrome / 加速度計 |
Research Abstract |
We used a 2-dimensional sagittal-plane gelatin brain model and a finite element simulation model to elucidate the mechanism underlying brain damage in shaken baby syndrome(SBS). In the gelatin brain model, strain stress was higher in the frontoparietal and occipitoparietal regions than midbrain, and stress-related changes could be observed in the frontoparietal region near the brain surface. In the simulation model, the effects of stress and strain were clearly seen in the intraparenchymal region near the lateral ventricle. These results suggest that brain damage such as gliding contusion or subdural hematoma occur in SBS.
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