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Reconstruction of skull defect by means of transport distraction osteogenesis with the aid of guided tissue regeneration method.

Research Project

Project/Area Number 21592292
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Plastic surgery
Research InstitutionIwate Medical University

Principal Investigator

HONDA Takayuki  岩手医科大学, 医学部, 助教 (30275549)

Co-Investigator(Kenkyū-buntansha) ARAI Yukihiko  岩手医科大学, 医学部, 助教 (20458178)
Co-Investigator(Renkei-kenkyūsha) KOBAYASHI Seiichiro  岩手医科大学, 医学部, 教授 (00295966)
SAWAI Takashi  岩手医科大学, 医学部, 教授 (00125577)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords再生医学 / 骨トランスポート法 / GTR法 / GBR法
Research Abstract

This study was aimed to reconstruct a skull defect by means of transport distraction osteogenesis. Based on "guided tissue regeneration method", we planned experimental study using rabbit skull. Transport distraction osteogenesis was performed on rabbit skull and the distraction site was covered with e-PTFE membrane. In our hypothesis, regenerate bone was not disturbed by surrounded soft tissue so that quality of new bone should be better than the regenerate that made by distraction without membrane. However, measurement of regenerate bone was not greater than regenerate made by conventional distraction without membrane.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (9 results)

All 2011 2010 2009

All Presentation (9 results)

  • [Presentation] 高度な下顎変形と頭蓋内への進展を伴った上顎体の1例2011

    • Author(s)
      本多孝之、工藤信、長尾宗朝、黒田敬、柏克彦、小林誠一郎
    • Organizer
      第29回日本頭蓋顎顔面外科学会
    • Place of Presentation
      グランドプリンスホテル高輪(東京)
    • Year and Date
      2011-11-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] Management of severe facial fractures associated with cranial fractures2011

    • Author(s)
      Honda T, Higuchi H, Kashiwa K, Yasuoka T, Kobayashi S
    • Organizer
      16th Congress of the International Confederation for Plastic Reconstructive and Aesthetic Surgery
    • Place of Presentation
      Vancouver, Canada
    • Year and Date
      2011-05-23
    • Related Report
      2011 Final Research Report
  • [Presentation] Management of severe facial fractures associated with cranial fractures2011

    • Author(s)
      Honda T, Higuchi H, Kashiwa K, Yasuoka T, Kobayashi S
    • Organizer
      16th Congress of the International Confederation for Plastic Reconstructive and Aesthetic Surgery
    • Place of Presentation
      Vancouver Convention Center, Vancouver, Canada
    • Year and Date
      2011-05-23
    • Related Report
      2011 Annual Research Report
  • [Presentation] Growing skull fractureの治療経験-造影MRIによる硬膜断端同定-2010

    • Author(s)
      本多孝之, 安岡智之, 新井雪彦, 柏克彦, 小林誠一郎
    • Organizer
      第28回日本頭蓋顎顔面外科学会学術集会
    • Place of Presentation
      京都
    • Year and Date
      2010-10-28
    • Related Report
      2011 Final Research Report
  • [Presentation] Growing skull fractureの治療経験-造影MRIによる硬膜断端同定-2010

    • Author(s)
      本多孝之、安岡智之、新井雪彦、柏克彦、小林誠一郎
    • Organizer
      第28回日本頭蓋顎顔面外科学会
    • Place of Presentation
      京都
    • Year and Date
      2010-10-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] Successful reconstruction of growing skull fracture : A Case Report2010

    • Author(s)
      Honda T., Yasuoka T., Arai Y., Kobayashi S., Omama S., Yoshida Y., Matsuura H.
    • Organizer
      The 8^<th> Asian Pacific Craniofacial Association Conference
    • Place of Presentation
      Sarawak, Malaysia
    • Year and Date
      2010-07-14
    • Related Report
      2010 Annual Research Report
  • [Presentation] Successful reconstruction of growing skull fracture : A case report2010

    • Author(s)
      Honda T, Yasuoka T, Arai Y, Kobayashi S, Omama S, Yoshida Y, Matsuura H, Kamei A, Akasaka M
    • Organizer
      15th ASEAN Congress of Plastic Surgery and 8th Asian Pacific Craniofacial Association Conference
    • Place of Presentation
      Kuching, Malaysia
    • Year and Date
      2010-07-13
    • Related Report
      2011 Final Research Report
  • [Presentation] Immunohistochemical Expression of Bone Morphogenic Protein-4 during Reconstruction of a Rabbit Skull Defect by Transport Distraction Osteogenesis2009

    • Author(s)
      Takayuki Honda, Seiichiro Kobayashi, Miwa Uzuki
    • Organizer
      The 10^<th> Congress of the International Confederation for Plastic and Reconstructive Surgery-Asian Pacific Section
    • Place of Presentation
      東京
    • Year and Date
      2009-10-08
    • Related Report
      2009 Annual Research Report
  • [Presentation] 骨トランスポート法による頭蓋骨欠損の再建新生骨に発現するBMPの局在と経時変化:ウサギ頭蓋骨による実験2009

    • Author(s)
      本多孝之、小林誠一郎
    • Organizer
      第18回日本形成外科学会基礎学術集会
    • Place of Presentation
      東京
    • Year and Date
      2009-10-01
    • Related Report
      2009 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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