Research Project
Grant-in-Aid for Challenging Exploratory Research
Residual bodies of lysosomes were found to be accumulated in the liver cells in the zebrafish mutant it768 in which endoplasmic reticulum (ER) stress were spontaneously upregulated. The results were interesting since accumulation of residual bodies had been implied to be associated with oxidative stress. To elucidate relationship between ER stress and oxidative stress, we generated and analyzed a mutant zebrafish of Nrf2, a master regulator of antioxidant genes, and the double mutant of Nrf2 and it768.
All 2011 2010 2009 Other
All Journal Article (13 results) (of which Peer Reviewed: 10 results) Presentation (29 results) Remarks (2 results)
PLoS One
Volume: 6 Issue: 10 Pages: e26884-e26884
10.1371/journal.pone.0026884
Development
Volume: 138 Issue: 24 Pages: 5357-5368
10.1242/dev.065565
Genes Cells
Volume: 16 Issue: 1 Pages: 46-57
10.1111/j.1365-2443.2010.01466.x
120007130821
PLoS ONE
Volume: 6
Volume: 16 Pages: 46-57
Dev.Growth Differ
Volume: 52 Issue: 2 Pages: 245-250
10.1111/j.1440-169x.2009.01168.x
10027563994
Chem. Biol
Volume: 17 Issue: 5 Pages: 419-420
10.1016/j.chembiol.2010.05.003
Curr. Biol.
Volume: 52 Pages: 245-250
Chem. Biol.
Volume: 17 Pages: 419-420
医学のあゆみ
Volume: 233 Pages: 639-640
Dev.Growth Differ. 52
Pages: 245-250
Proc. Natl. Acad.Sci
Volume: 106 Issue: 43 Pages: 18309-18414
10.1073/pnas.0708837106
Proc.Natl.Acad.Sci.USA 106
Pages: 18309-18414
http://www.md.tsukuba.ac.jp/MDBiology/mdbiol.index.html