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Metabolomics for elucidation of wine evaluation

Research Project

Project/Area Number 21700739
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Eating habits, studies on eating habits
Research InstitutionUniversity of Yamanashi

Principal Investigator

HISAMOTO Masashi  University of Yamanashi, 大学院・医学工学総合研究部, 助教 (00377590)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Keywordsワイン / 食品 / メタボロミクス
Research Abstract

Applications of metabolomics techniques along with chemometrics provide an understanding in the relationship between metabolome of red wine and its quality. Ultra-performance liquid chromatography coupled with time-of-flight mass spectrometry (UPLC-TOFMS) allowed a high-throughput analysis. Using this technique, a wide range of metabolites were investigated. A set of red wines during bottle storage was analyzed. Red wines with different storage time were discriminated through orthogonal partial least squares discriminate analysis (OPLS-DA). Furthermore, grape anthocyanins and pyranoanthocyanins detected in red wine were found to be significant markers to bottle aging.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (13 results)

All 2011 2010 2009 Other

All Journal Article (7 results) (of which Peer Reviewed: 7 results) Presentation (4 results) Remarks (2 results)

  • [Journal Article] オンラインDPPH-HPLC法によるブドウ種子フェノール中の抗酸化化合物の探索2011

    • Author(s)
      久本 雅嗣、市川 茉利枝、依田 諭、小林浩武、奥田 徹
    • Journal Title

      日本ブドウ・ワイン学会誌 Vol.22, No.1

    • NAID

      40018946676

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Differential neuroprotective activity of two different grape seed extracts.2011

    • Author(s)
      Keishi Narita, Masashi Hisamoto, Tohru Okuda, Sen Takeda.
    • Journal Title

      PLoS ONE Vol.6, No.3

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Antioxidant Activity of Various Part of Koshu Grape2011

    • Author(s)
      Masashi HISAMOTO, Hirokazu MUNEDA, Tohru OKUDA
    • Journal Title

      Journal of ASEV Japan Vol.22 in press

    • NAID

      40019202360

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Differential neuroprotective activity of two different grape seed extracts.2011

    • Author(s)
      Keishi Narita, 他3名
    • Journal Title

      PLoS ONE

      Volume: 6 Pages: 1-10

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] オンラインDPPH-HPLC法によるブドウ種子フェノール中の抗酸化化合物の探索2011

    • Author(s)
      久本雅嗣, 他4名
    • Journal Title

      日本ブドウ・ワイン学会誌

      Volume: 22(印刷中)

    • NAID

      40018946676

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Phenolic off flavor characterization of commercially available wine yeasts and selection of the yeast for Koshu winemaking.2010

    • Author(s)
      Masashi Hisamoto, Taiyo Furuya, Akiko Nakagawa, Fujitoshi Yanagida, Tohru Okuda, Michikatsu Sato
    • Journal Title

      Journal of ASEV Japan Vol.21, No.3

      Pages: 112-117

    • NAID

      40018702175

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Phenolic off flavor characterization of commercially available wine yeasts and selection of the yeast for Koshu winemaking.2010

    • Author(s)
      Masashi Hisamoto, 他5名
    • Journal Title

      Journal of ASEV Japan

      Volume: 21 Pages: 112-117

    • NAID

      40018702175

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] 赤ワインの熟成と成分のメタボローム解析2010

    • Author(s)
      久本 雅嗣, 藤原 陽, 古屋 太陽, 奥田 徹
    • Organizer
      第5回メタボロームシンポジウム
    • Place of Presentation
      山形県鶴岡市
    • Year and Date
      2010-09-10
    • Related Report
      2010 Final Research Report
  • [Presentation] 赤ワインの熟成と成分のメタボローム解析2010

    • Author(s)
      久本雅嗣, 他3名
    • Organizer
      第5回メタボロームシンポジウム
    • Place of Presentation
      グランドエル・サン(山形県鶴岡市)
    • Year and Date
      2010-09-10
    • Related Report
      2010 Annual Research Report
  • [Presentation] 生育中の甲州種ブドウに含まれるフェノール性化合物の変化2009

    • Author(s)
      古屋 太陽,久本 雅嗣,勝亦 秀和,杉山啓介,佐藤 充克,奥田 徹
    • Organizer
      日本ブドウ・ワイン学会
    • Place of Presentation
      東広島市
    • Year and Date
      2009-11-21
    • Related Report
      2010 Final Research Report
  • [Presentation] 生育中の甲州種ブドウに含まれるフェノール性化合物の変化2009

    • Author(s)
      久本雅嗣, 他5名
    • Organizer
      日本ブドウ・ワイン学会
    • Place of Presentation
      広島大学(広島)
    • Year and Date
      2009-11-21
    • Related Report
      2009 Annual Research Report
  • [Remarks] ホームページ等

    • URL

      http://erdb.yamanashi.ac.jp/rdb/A_DispInfo.Scholar/0/AB357CCA12C1C0CF.html

    • Related Report
      2010 Final Research Report
  • [Remarks]

    • URL

      http://erdb.yamanashi.ac.jp/rdb/A_DispInfo.Scholar/0/AB357CCA12C1C0CF.html

    • Related Report
      2010 Annual Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

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