Research on two-wavelength fluorescence immunosensor system using multispot surface-emitting integrated semiconductor lasers

Research Project

Project/Area Number	21710125
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Microdevices/Nanodevices
Research Institution	Osaka University
Principal Investigator	UEMUKAI Masahiro Osaka University, 工学研究科, 助教 (80362672)
Project Period (FY)	2009 – 2010
Project Status	Completed (Fiscal Year 2010)
Budget Amount *help	¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000) Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000) Fiscal Year 2009: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords	半導体レーザ / 光集積デバイス / 微小流路 / 蛍光検出 / 免疫センサ
Research Abstract	Compact and low-cost semiconductor laser-induced fluorescence detection systems for simultaneous multiple detection can be realized by combination of grating coupled surface-emitting lasers and microfluidic structures. We designed and fabricated red and near-infrared distributed Bragg reflector lasers integrated with the phase-shifted grating coupler for multisport focusing. 5×5 and 7×7 spot arrays were obtained from the red integrated laser. The grating coupler designed for near-infrared light also emitted a multispot array. By combination of the semiconductor lasers, dual-band filter and fluorescence dyes for red and near-infrared light, preliminary test of two-wavelength semiconductor laser-induced fluorescence detection was demonstrated.