Proteomic analysis of anhydrobiotic and extremotolerant animal
| Project/Area Number |
21710223
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Living organism molecular science
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| Research Institution | The University of Tokyo |
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Principal Investigator |
國枝 武和 The University of Tokyo, 大学院・理学系研究科, 助教 (10463879)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
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| Keywords | プロテオミクス / クマムシ / 極限環境耐性 / 乾眠 / 放射線耐性 / クロマチン / 抗凝集性 / 円偏光二色性 / タンパク質 / プロテオーム / 蛋白質 / 動物 / 親水性 |
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| Research Abstract |
We identified several novel anti-aggregation proteins from an anhydrobiotic tardigrade, Ramazzottius varieornatus and revealed that these proteins were expressed abundantly even in active state. Although these proteins were found in less-tolerant taridirades, there are some correlation between their denaturing temperature and desiccation-tolerance. Our identified proteins are good basis to elucidate the molecular mechanism of anhydrobiotic ability and extremotolerance of tardigrades.
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Report
(3 results)
Research Products
(16 results)
