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Optimization of Drug Movement in Tape for Percutaneous Absorption on Electrical Control

Research Project

Project/Area Number 21760314
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Measurement engineering
Research InstitutionToyohashi University of Technology

Principal Investigator

MURAKAMI Yoshinobu  Toyohashi University of Technology, 大学院・工学研究科, 准教授 (10342495)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Keywordsアクリル系粘着剤 / 薬物 / 経皮吸収テープ / 赤外吸収スペクトル / 空間電荷 / 電気的制御 / 薬物挙動
Research Abstract

To investigate a possibility of electrical control of a drug in a tape for percutaneous absorption, a space charge distribution using by a pulsed electroacoustic method in a tape were measured. It was observed that negative charge, which might be corresponding to a drug, moved from a tape with a drug to a tape without a drug on an experiment using a multi-layer sample. From the chemical analysis, it was considered that the negative charge might agree with the drug. From these results, it was suggested that there was a possibility that the electrical field would control the movement of a drug.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (6 results)

All 2010 Other

All Journal Article (1 results) Presentation (3 results) Remarks (2 results)

  • [Journal Article] 経皮吸収テープ中の薬物挙動における電気的制御の可能性の検討2010

    • Author(s)
      清水雄哉、村上義信、栗本宗明、長尾雅行
    • Journal Title

      電気学会研究会資料 誘電・絶縁材料研究会DEI-10-074~080

      Pages: 13-17

    • NAID

      10030320963

    • Related Report
      2010 Annual Research Report
  • [Presentation] 経皮吸収型テープ製剤中の薬物が空間電荷分布に及ぼす影響2010

    • Author(s)
      清水雄哉、村上義信、長尾雅行
    • Organizer
      平成22年度電気関係学会東海支部連合大会 講演論文集,No.A2-5
    • Place of Presentation
      (CD-ROM)
    • Related Report
      2010 Final Research Report
  • [Presentation] 経皮吸収テープ中の薬物挙動における電気的制御の可能性の検討2010

    • Author(s)
      清水雄哉、村上義信、栗本宗明、長尾雅行
    • Organizer
      電気学会研究会資料誘電\絶縁材料研究会 DEI-10-074~080,No.DEI-10-078
    • Related Report
      2010 Final Research Report
  • [Presentation] 経皮吸収型テープ製剤中の薬物が空間電荷分布に及ぼす影響2010

    • Author(s)
      清水雄哉、村上義信、長尾雅行
    • Organizer
      平成22年度 電気関係学会東海支部連合大会 講演論文集
    • Place of Presentation
      中部大学(CD-ROM)
    • Related Report
      2010 Annual Research Report
  • [Remarks] ホームページ等

    • URL

      http://dei.ee.tut.ac.jp

    • Related Report
      2010 Final Research Report
  • [Remarks]

    • URL

      http://www.dei.ee.tut.ac.jp

    • Related Report
      2010 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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