BMP-switching regulates lineage specification and migration of neural crest cells
| Project/Area Number |
21770235
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Developmental biology
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| Research Institution | Nara Institute of Science and Technology |
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Principal Investigator |
SAITO Daisuke Nara Institute of Science and Technology, バイオサイエンス研究科, 助教 (90403360)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2009: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 神経堤細胞 / 交感神経 / 副腎 / ケモカイン / 誘引 / 細胞移動 / 反発 / 細胞選別 / 神経冠細胞 |
|---|
| Research Abstract |
Among the neural crest cell (NCC) subtypes, I focus on the sympatho-adrenal progenitor cells (SA cells), the common progenitors giving rise to sympathetic neurons (S-cells) and adrenal medulla cells (A-cells). We found that the mechanism underling SA cells migration toward dorsal aorta (DA), and BMP, SDF and Neuregulin is involved in this process.
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Report
(3 results)
Research Products
(19 results)
