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Induction mechanism of peripheral nervous system in ascidian

Research Project

Project/Area Number 21770252
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Developmental biology
Research InstitutionNational Institute of Advanced Industrial Science and Technology

Principal Investigator

OHTSUKA Yukio  独立行政法人産業技術総合研究所, バイオメディカル研究部門, 研究員 (90344192)

Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords進化発生 / ホヤ / 誘導 / nodalシグナル / 転写調節
Research Abstract

In order to understand the induction of ascidian peripheral nervous system, I investigated the role of nodal signaling pathway in neural plate border induction. My results show that nodal regulates the specification of ascidian peripheral neurons via induction of chordin and BMPs in neural plate border. In addition, I isolate the cis-regulatory elements of nodal target genes, ci-chordin and ci-Pax3/7, and identify their nodal response elements.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report

Research Products

(3 results)

All 2010 2009

All Presentation

  • [Presentation] マボヤ神経板におけるBMPシグナル分子の発現2010

    • Author(s)
      大塚幸雄
    • Organizer
      日本動物学会第81回大会
    • Place of Presentation
      東京大学(東京)
    • Year and Date
      2010-09-23
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] The specification of trunk epidermal sensory neuron in Halocynthia embryos2009

    • Author(s)
      Yukio Ohtsuka
    • Organizer
      The 5th International Tunicate meeting
    • Place of Presentation
      沖縄産業支援センター(沖縄)
    • Year and Date
      2009-06-22
    • Related Report
      2011 Final Research Report
  • [Presentation] The specification of the trunk epidermal sensory neuron in Halocynthia embryos2009

    • Author(s)
      大塚幸雄
    • Organizer
      The 5th International Tunicate meeting
    • Place of Presentation
      沖縄産業支援センター(沖縄)
    • Year and Date
      2009-06-22
    • Related Report
      2009 Annual Research Report

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Published: 2009-03-31   Modified: 2016-04-21  

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