Studies on molecular mechanisms regulating intercellular communication in filamentous fungi, multicellular organisms
| Project/Area Number |
21780065
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Applied microbiology
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| Research Institution | The University of Tokyo |
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Principal Investigator |
MARUYAMA Jun-ichi 東京大学, 大学院・農学生命科学研究科, 助教 (00431833)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
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| Keywords | 糸状菌 / 多細胞生物 / 細胞質連絡 / 隔壁孔 / 麹菌 / ペルオキシソーム / ビタミン / ビオチン |
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| Research Abstract |
Filamentous fungi grow as multicellular organisms, in which flanking cells communicate with each other via the septal pore. This project aimed to elucidate molecular mechanisms regulating the intercellular communication. AoSO that aggregates at the septal pore in response to stresses, and we identified protein regions responsible for the stress-responsive aggregation at the septal pore. Novel proteins localizing at the septal pore were identified through a screening for AoFus3 MAP kinase-interacting proteins.
We discovered a novel function of peroxisomes for biotin biosynthesis during investigating biogenesis processes of Woronin body, an organelle that regulates the intercellular communication.
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Report
(3 results)
Research Products
(27 results)
