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Molecular mechanism of feeding regulation in larval fish

Research Project

Project/Area Number 21780181
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field General fisheries
Research InstitutionKitasato University

Principal Investigator

MIZUSAWA Kanta  北里大学, 海洋生命科学部, 講師 (70458743)

Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords遺伝子 / ゼブラフィッシュ / 仔魚 / 摂食 / 成長 / 発光ダイオード / マイクロアレイ / メラニン凝集ホルモン / 孵化仔魚 / LED / MCH / 食欲 / 摂餌 / 受容体 / 光 / 背地応答 / 転写調節
Research Abstract

This study shows that the feeding and growth of larval zebrafish are modified by certain wavelengths and some hormone-relating genes, which include melanin-concentrating hormone, exhibit changes in expression levels in response to certain wavelengths. Molecular cloning has identified a mammalian-type melanin-concentrating hormone receptor, which is expressed in the brain but not in the skin.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (11 results)

All 2012 2011 2010 2009 Other

All Journal Article (6 results) (of which Peer Reviewed: 4 results) Presentation (4 results) Remarks (1 results)

  • [Journal Article] Food deprivation increases the expression of the prepro-orexin gene in the hypothalamus of the barfin flounder2012

    • Author(s)
      Amiya N, Mizusawa K, Kobayashi Y, Yamanome T, Amano M, Takahashi A
    • Journal Title

      Verasper moseri. Zool. Sci.

      Volume: 29 Issue: 1 Pages: 42-48

    • DOI

      10.2108/zsj.29.43

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] 魚類・光・内分泌~体色と食欲の深い仲2011

    • Author(s)
      高橋明義, 小林勇喜, 山野目健, 水澤寛太
    • Journal Title

      ビオフィリア

      Volume: 7 Pages: 31-36

    • URL

      http://annex.biophilia.jp/index.php/biophilia/article/view/397

    • Related Report
      2011 Final Research Report
  • [Journal Article] Signalling pathway of goldfish melanin-concentrating hormone receptors 1 and 22011

    • Author(s)
      Hamamoto A, Mizusawa K, Takahashi A, Saito Y
    • Journal Title

      Regul. Pept.

      Volume: 169 Issue: 1-3 Pages: 6-12

    • DOI

      10.1016/j.regpep.2011.04.001

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Inhibiting roles of melanin-concentrating hormone for skin pigment dispersion in barfin flounder, Verasper moseri2011

    • Author(s)
      Mizusawa, K., Kobayashi, Y., Sunuma, T., Asahida, T., Saito, Y., Takahashi, A.
    • Journal Title

      General and Comparative Endocrinology

      Volume: 171 Pages: 75-81

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Molecular cloning and expression of two melanin-concentrating hormone receptors mgoldfish2009

    • Author(s)
      Mizusawa K
    • Journal Title

      Peptides 30

      Pages: 1990-1996

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] キンギョ・メラニン凝集ホルモン受容体の同定と発現解析2009

    • Author(s)
      水澤寛太
    • Journal Title

      比較内分泌学 35

      Pages: 308-311

    • NAID

      10025870764

    • Related Report
      2009 Annual Research Report
  • [Presentation] The MCH System of Shark is More Closely Related to the MCH System of Mammals than That of Teleosts2012

    • Author(s)
      Mizusawa K
    • Organizer
      The 7th Congress of the Asia and Oceania Society for Comparative Endocrinology
    • Place of Presentation
      Kuala Lumpur, Malaysia
    • Year and Date
      2012-03-05
    • Related Report
      2011 Final Research Report
  • [Presentation] マツカワ体色調節における2型メラニン凝集ホルモンの役割2010

    • Author(s)
      水澤寛太、小林勇喜、須沼俊和、齋藤大輔、高橋明義
    • Organizer
      第35回日本比較内分泌学会
    • Place of Presentation
      グランシップ 静岡県コンベンションアーツセンター(静岡市)
    • Year and Date
      2010-11-19
    • Related Report
      2010 Annual Research Report
  • [Presentation] シュモクザメのメラニン凝集ホルモン受容体のcDNAクローニング2010

    • Author(s)
      水澤寛太
    • Organizer
      日本水産学会春季大会
    • Place of Presentation
      日本大学藤沢キャンパス(神奈川県)
    • Year and Date
      2010-03-29
    • Related Report
      2009 Annual Research Report
  • [Presentation] Characterization of two melanin-concentrating hormone receptor subtypes in gold fish2009

    • Author(s)
      Mizusawa K
    • Organizer
      16th International Congress of Comparative Endocrinology
    • Place of Presentation
      The University of Hong Kong(Hong Kong)
    • Year and Date
      2009-06-23
    • Related Report
      2009 Annual Research Report
  • [Remarks] ホームページ等研究代表者の所属する研究室のホームページ

    • URL

      http://www.kitasato-u.ac.jp/fish/contents/lab/l12/index.htm

    • Related Report
      2011 Final Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

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