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Effects of serum VEGF levels on 4-year weight changes in Japanese male workers

Research Project

Project/Area Number 21790564
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Hygiene
Research InstitutionFukuoka University

Principal Investigator

IMATOH Takuya  福岡大学, 医学部, 講師 (20368989)

Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords肥満 / 血管内皮細胞増殖因子(VEGF) / 疫学研究 / 生活習慣病 / 血管内皮細胞増殖因子 / 血管新生
Research Abstract

I carried out an epidemiological study and investigated whether serum VEGF levels are associated with obesity and whether they effect weight change in future.
I found that subjects with the highest quartile of serum VEGF level have significantly highest prevalence of obesity in quartiles(37.1%). Logistic regression showed that adjusted odds ratios of subjects with highest quartile had 1.27(95% C. I ; 0.86-1, 88). Significant dose-response relationships were founded(p<0.05). Finally, Adjusted means of weight change with lowest VEGF levels increased 0.1kg, in contrast, those of the other subjects increased more than 0.5kg.
These data suggested that increased VEGF levels led to weight gain in future.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report

Research Products

(6 results)

All 2011 2010

All Presentation

  • [Presentation] コーヒーと緑茶摂取量とレプチン濃度との関連に関する疫学研究2011

    • Author(s)
      今任拓也
    • Organizer
      第32回肥満学会
    • Place of Presentation
      兵庫県・明石夢舞台国際会議場
    • Year and Date
      2011-09-23
    • Related Report
      2011 Final Research Report
  • [Presentation] コーヒーと緑茶摂取量とレプチン濃度との関連に関する疫学研究2011

    • Author(s)
      今任拓也
    • Organizer
      第32回日本肥満学会
    • Place of Presentation
      淡路夢舞台国際会議場(淡路市)
    • Year and Date
      2011-09-22
    • Related Report
      2011 Annual Research Report
  • [Presentation] 血管内皮増殖因子VEGFと肥満との関連に関する横断研究2010

    • Author(s)
      今任拓也
    • Organizer
      第31回肥満学会
    • Place of Presentation
      群馬県・前橋テルサ
    • Year and Date
      2010-10-02
    • Related Report
      2011 Final Research Report
  • [Presentation] 血管内皮増殖因子VEGFと肥満との関連に関する横断研究2010

    • Author(s)
      今任拓也
    • Organizer
      第31回日本肥満学会
    • Place of Presentation
      前橋テルサ(群馬県)
    • Year and Date
      2010-10-02
    • Related Report
      2010 Annual Research Report
  • [Presentation] Measurement of high-molecular weight adiponectin is not useful in assessing coronary stenosis2010

    • Author(s)
      今任拓也
    • Organizer
      The joint scientific meeting of the international epidemiological association western pacific region and the Japan epidemiological association
    • Place of Presentation
      埼玉県・埼玉県立大学
    • Year and Date
      2010-01-09
    • Related Report
      2011 Final Research Report
  • [Presentation] Measurement of high-molecular weight adiponectin is not useful in assessing coronary stenosis2010

    • Author(s)
      今任拓也
    • Organizer
      The joint scientific meeting of the international epidemiological association western pacific region and the Japan epidemiological association
    • Place of Presentation
      埼玉県立大学
    • Related Report
      2009 Annual Research Report

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Published: 2009-03-31   Modified: 2016-04-21  

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