| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Research Abstract |
The objective of this study was to investigate about the relation between endothelial vesicle structures and endothelial function. This study demonstrated that vesicle structures detected in endothelial cytoplasm were the platform which modify the endothelial function through redox signaling or in lipid raft dependent manner. In addition, microparticle, extracellular vesicle structure which was derived from endothelial cell, was suggested to be also related with intracellular vesicle structure and have characteristics of proatherogenic properties.
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